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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MUL1
Full Name:
Mitochondrial ubiquitin ligase activator of NFKB 1
Alias:
E3 ubiquitin-protein ligase MUL1;Growth inhibition and death E3 ligase;Mitochondrial-anchored protein ligase;Putative NF-kappa-B-activating protein 266;RING finger protein 218
Type:
Mass (Da):
39800
Number AA:
352
UniProt ID:
Q969V5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
E
S
G
G
R
P
S
L
C
Site 2
S36
Y
R
Q
K
A
R
V
S
Q
E
L
K
G
A
K
Site 3
S53
H
L
G
E
D
L
K
S
I
L
S
E
A
P
G
Site 4
S56
E
D
L
K
S
I
L
S
E
A
P
G
K
C
V
Site 5
S74
V
I
E
G
A
V
R
S
V
K
E
T
L
N
S
Site 6
T78
A
V
R
S
V
K
E
T
L
N
S
Q
F
V
E
Site 7
S81
S
V
K
E
T
L
N
S
Q
F
V
E
N
C
K
Site 8
T95
K
G
V
I
Q
R
L
T
L
Q
E
H
K
M
V
Site 9
S147
R
V
L
K
P
L
D
S
V
D
L
G
L
E
T
Site 10
T154
S
V
D
L
G
L
E
T
V
Y
E
K
F
H
P
Site 11
Y156
D
L
G
L
E
T
V
Y
E
K
F
H
P
S
I
Site 12
S162
V
Y
E
K
F
H
P
S
I
Q
S
F
T
D
V
Site 13
S165
K
F
H
P
S
I
Q
S
F
T
D
V
I
G
H
Site 14
Y173
F
T
D
V
I
G
H
Y
I
S
G
E
R
P
K
Site 15
S175
D
V
I
G
H
Y
I
S
G
E
R
P
K
G
I
Site 16
S207
E
L
V
L
D
N
N
S
V
R
L
Q
P
P
K
Site 17
Y219
P
P
K
Q
G
M
Q
Y
Y
L
S
S
Q
D
F
Site 18
Y220
P
K
Q
G
M
Q
Y
Y
L
S
S
Q
D
F
D
Site 19
S222
Q
G
M
Q
Y
Y
L
S
S
Q
D
F
D
S
L
Site 20
S223
G
M
Q
Y
Y
L
S
S
Q
D
F
D
S
L
L
Site 21
S228
L
S
S
Q
D
F
D
S
L
L
Q
R
Q
E
S
Site 22
S235
S
L
L
Q
R
Q
E
S
S
V
R
L
W
K
V
Site 23
S236
L
L
Q
R
Q
E
S
S
V
R
L
W
K
V
L
Site 24
Y263
F
F
I
L
R
K
Q
Y
L
Q
R
Q
E
R
L
Site 25
S288
E
H
E
A
Q
L
L
S
R
A
K
P
E
D
R
Site 26
S297
A
K
P
E
D
R
E
S
L
K
S
A
C
V
V
Site 27
S300
E
D
R
E
S
L
K
S
A
C
V
V
C
L
S
Site 28
Y350
I
T
R
V
I
P
L
Y
N
S
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation