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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CIRH1A
Full Name:
Cirhin
Alias:
CIR1A; Cirhin; FLJ14728; KIAA1988; NAIC; Testis expressed gene 292; TEX292
Type:
Unknown function
Mass (Da):
76890
Number AA:
686
UniProt ID:
Q969X6
International Prot ID:
IPI00239815
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005730
GO:0043226
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y14
H
R
V
R
F
F
N
Y
V
P
S
G
I
R
C
Site 2
Y24
S
G
I
R
C
V
A
Y
N
N
Q
S
N
R
L
Site 3
S28
C
V
A
Y
N
N
Q
S
N
R
L
A
V
S
R
Site 4
T39
A
V
S
R
T
D
G
T
V
E
I
Y
N
L
S
Site 5
Y49
I
Y
N
L
S
A
N
Y
F
Q
E
K
F
F
P
Site 6
T63
P
G
H
E
S
R
A
T
E
A
L
C
W
A
E
Site 7
S76
A
E
G
Q
R
L
F
S
A
G
L
N
G
E
I
Site 8
T131
S
V
K
L
F
Q
I
T
P
D
K
I
Q
F
E
Site 9
S146
R
N
F
D
R
Q
K
S
R
I
L
S
L
S
W
Site 10
S150
R
Q
K
S
R
I
L
S
L
S
W
H
P
S
G
Site 11
S152
K
S
R
I
L
S
L
S
W
H
P
S
G
T
H
Site 12
S156
L
S
L
S
W
H
P
S
G
T
H
I
A
A
G
Site 13
Y188
K
M
I
V
D
R
Q
Y
M
G
V
S
K
R
K
Site 14
S192
D
R
Q
Y
M
G
V
S
K
R
K
C
I
V
W
Site 15
S223
G
K
V
Q
F
W
D
S
A
T
G
T
L
V
K
Site 16
T269
H
F
Q
L
V
P
V
T
S
N
S
S
E
K
Q
Site 17
S270
F
Q
L
V
P
V
T
S
N
S
S
E
K
Q
W
Site 18
S272
L
V
P
V
T
S
N
S
S
E
K
Q
W
V
R
Site 19
T292
H
H
T
H
D
V
R
T
V
A
H
S
P
T
A
Site 20
Y323
E
K
V
E
V
K
N
Y
D
A
A
L
R
K
I
Site 21
S339
F
P
H
R
C
L
I
S
C
S
K
K
R
Q
L
Site 22
S341
H
R
C
L
I
S
C
S
K
K
R
Q
L
L
L
Site 23
S362
L
E
L
W
R
L
G
S
T
V
A
T
G
K
N
Site 24
T363
E
L
W
R
L
G
S
T
V
A
T
G
K
N
G
Site 25
T366
R
L
G
S
T
V
A
T
G
K
N
G
D
T
L
Site 26
T372
A
T
G
K
N
G
D
T
L
P
L
S
K
N
A
Site 27
S376
N
G
D
T
L
P
L
S
K
N
A
D
H
L
L
Site 28
T387
D
H
L
L
H
L
K
T
K
G
P
E
N
I
I
Site 29
Y416
T
V
S
R
F
F
L
Y
R
L
N
Y
E
H
D
Site 30
Y420
F
F
L
Y
R
L
N
Y
E
H
D
N
I
S
L
Site 31
S426
N
Y
E
H
D
N
I
S
L
K
R
V
S
K
M
Site 32
S431
N
I
S
L
K
R
V
S
K
M
P
A
F
L
R
Site 33
S502
D
G
N
W
L
A
A
S
G
T
S
A
G
V
H
Site 34
Y511
T
S
A
G
V
H
V
Y
N
V
K
Q
L
K
L
Site 35
T521
K
Q
L
K
L
H
C
T
V
P
A
Y
N
F
P
Site 36
Y553
S
D
Q
Q
V
F
E
Y
S
I
P
D
K
Q
Y
Site 37
Y560
Y
S
I
P
D
K
Q
Y
T
D
W
S
R
T
V
Site 38
T561
S
I
P
D
K
Q
Y
T
D
W
S
R
T
V
Q
Site 39
T581
H
L
W
L
Q
R
D
T
P
I
T
H
I
S
F
Site 40
T584
L
Q
R
D
T
P
I
T
H
I
S
F
H
P
K
Site 41
Y602
H
I
L
L
H
D
A
Y
M
F
C
I
I
D
K
Site 42
T618
L
P
L
P
N
D
K
T
L
L
Y
N
P
F
P
Site 43
Y621
P
N
D
K
T
L
L
Y
N
P
F
P
P
T
N
Site 44
T627
L
Y
N
P
F
P
P
T
N
E
S
D
V
I
R
Site 45
T637
S
D
V
I
R
R
R
T
A
H
A
F
K
I
S
Site 46
T660
M
D
L
L
D
E
R
T
L
V
A
V
E
R
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation