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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CPNE4
Full Name:
Copine-4
Alias:
Copine IV;Copine-8
Type:
Mass (Da):
62395
Number AA:
557
UniProt ID:
Q96A23
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S36
R
V
A
C
K
G
I
S
D
R
D
A
L
S
K
Site 2
S42
I
S
D
R
D
A
L
S
K
P
D
P
C
V
I
Site 3
Y75
R
T
C
I
N
P
V
Y
S
K
L
F
T
V
D
Site 4
T80
P
V
Y
S
K
L
F
T
V
D
F
Y
F
E
E
Site 5
Y84
K
L
F
T
V
D
F
Y
F
E
E
V
Q
R
L
Site 6
S99
R
F
E
V
H
D
I
S
S
N
H
N
G
L
K
Site 7
S100
F
E
V
H
D
I
S
S
N
H
N
G
L
K
E
Site 8
S123
C
T
L
G
Q
I
V
S
Q
R
K
L
S
K
S
Site 9
S128
I
V
S
Q
R
K
L
S
K
S
L
L
K
H
G
Site 10
S130
S
Q
R
K
L
S
K
S
L
L
K
H
G
N
T
Site 11
T137
S
L
L
K
H
G
N
T
A
G
K
S
S
I
T
Site 12
Y156
E
L
S
G
N
D
D
Y
V
E
L
A
F
N
A
Site 13
S173
L
D
D
K
D
F
F
S
K
S
D
P
F
L
E
Site 14
S175
D
K
D
F
F
S
K
S
D
P
F
L
E
I
F
Site 15
T189
F
R
M
N
D
D
A
T
Q
Q
L
V
H
R
T
Site 16
S204
E
V
V
M
N
N
L
S
P
A
W
K
S
F
K
Site 17
S209
N
L
S
P
A
W
K
S
F
K
V
S
V
N
S
Site 18
S213
A
W
K
S
F
K
V
S
V
N
S
L
C
S
G
Site 19
S216
S
F
K
V
S
V
N
S
L
C
S
G
D
P
D
Site 20
S247
D
F
I
G
E
F
T
S
T
F
K
E
M
R
G
Site 21
T248
F
I
G
E
F
T
S
T
F
K
E
M
R
G
A
Site 22
Y270
W
E
C
I
N
P
K
Y
K
A
K
K
K
N
Y
Site 23
S280
K
K
K
N
Y
K
N
S
G
T
V
I
L
N
L
Site 24
T315
F
T
V
A
I
D
F
T
A
S
N
G
D
P
R
Site 25
S324
S
N
G
D
P
R
N
S
C
S
L
H
Y
I
H
Site 26
Y329
R
N
S
C
S
L
H
Y
I
H
P
Y
Q
P
N
Site 27
Y333
S
L
H
Y
I
H
P
Y
Q
P
N
E
Y
L
K
Site 28
Y352
V
G
E
I
C
Q
D
Y
D
S
D
K
M
F
P
Site 29
Y371
G
A
R
I
P
P
E
Y
T
V
S
H
D
F
A
Site 30
S423
I
I
Q
K
V
A
K
S
A
S
E
E
T
N
T
Site 31
T430
S
A
S
E
E
T
N
T
K
E
A
S
Q
Y
F
Site 32
S434
E
T
N
T
K
E
A
S
Q
Y
F
I
L
L
I
Site 33
S478
G
V
G
N
A
D
F
S
D
M
Q
M
L
D
G
Site 34
S492
G
D
D
G
I
L
R
S
P
K
G
E
P
V
L
Site 35
S515
F
R
N
F
K
H
A
S
P
A
A
L
A
K
S
Site 36
Y534
V
P
N
Q
V
V
D
Y
Y
N
G
K
G
I
K
Site 37
Y535
P
N
Q
V
V
D
Y
Y
N
G
K
G
I
K
P
Site 38
S545
K
G
I
K
P
K
C
S
S
E
M
Y
E
S
S
Site 39
S546
G
I
K
P
K
C
S
S
E
M
Y
E
S
S
R
Site 40
Y549
P
K
C
S
S
E
M
Y
E
S
S
R
T
L
A
Site 41
S551
C
S
S
E
M
Y
E
S
S
R
T
L
A
P
_
Site 42
S552
S
S
E
M
Y
E
S
S
R
T
L
A
P
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation