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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
JAKMIP2
Full Name:
Janus kinase and microtubule-interacting protein 2
Alias:
CTCL tumor antigen HD-CL-04;Neuroendocrine long coiled-coil protein 1
Type:
Mass (Da):
94934
Number AA:
810
UniProt ID:
Q96AA8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T28
A
A
N
E
D
L
R
T
K
L
T
D
I
Q
I
Site 2
T31
E
D
L
R
T
K
L
T
D
I
Q
I
E
L
H
Site 3
S42
I
E
L
H
Q
E
K
S
K
V
S
K
L
E
R
Site 4
T52
S
K
L
E
R
E
K
T
Q
E
A
K
R
I
R
Site 5
T67
E
L
E
Q
R
K
H
T
V
L
V
T
E
L
K
Site 6
S101
K
Q
H
E
Q
E
M
S
R
T
V
K
V
R
D
Site 7
T103
H
E
Q
E
M
S
R
T
V
K
V
R
D
G
E
Site 8
S116
G
E
I
Q
R
L
K
S
A
L
C
A
L
R
D
Site 9
S125
L
C
A
L
R
D
G
S
S
D
K
V
R
T
A
Site 10
S126
C
A
L
R
D
G
S
S
D
K
V
R
T
A
L
Site 11
T147
E
A
R
K
L
F
D
T
E
R
L
K
L
L
Q
Site 12
S186
I
K
A
G
D
L
R
S
E
H
Q
S
H
Q
E
Site 13
S190
D
L
R
S
E
H
Q
S
H
Q
E
A
I
S
K
Site 14
S196
Q
S
H
Q
E
A
I
S
K
I
K
W
E
S
E
Site 15
S202
I
S
K
I
K
W
E
S
E
R
D
I
R
R
L
Site 16
S222
A
K
D
R
I
I
F
S
L
E
K
E
L
E
T
Site 17
Y233
E
L
E
T
Q
T
G
Y
V
Q
K
L
Q
L
Q
Site 18
S259
K
E
A
E
C
N
M
S
S
P
K
R
E
I
P
Site 19
S260
E
A
E
C
N
M
S
S
P
K
R
E
I
P
G
Site 20
S273
P
G
R
A
G
D
G
S
E
H
C
S
S
P
D
Site 21
S277
G
D
G
S
E
H
C
S
S
P
D
L
R
R
N
Site 22
S278
D
G
S
E
H
C
S
S
P
D
L
R
R
N
Q
Site 23
T294
R
I
A
E
L
N
A
T
I
R
K
L
E
D
R
Site 24
T303
R
K
L
E
D
R
N
T
L
L
G
D
E
R
N
Site 25
T319
L
L
K
R
V
R
E
T
E
K
Q
C
K
P
L
Site 26
S343
R
N
D
E
L
M
V
S
L
Q
R
M
E
E
K
Site 27
S359
K
A
V
T
K
E
N
S
E
M
R
E
K
I
T
Site 28
T366
S
E
M
R
E
K
I
T
S
H
P
P
L
K
K
Site 29
S367
E
M
R
E
K
I
T
S
H
P
P
L
K
K
L
Site 30
S376
P
P
L
K
K
L
K
S
L
N
D
L
D
Q
A
Site 31
T389
Q
A
N
E
E
Q
E
T
E
F
L
K
L
Q
V
Site 32
T407
Q
N
I
I
D
E
L
T
R
D
R
E
K
L
I
Site 33
S422
R
R
R
K
H
R
R
S
S
K
P
I
K
R
P
Site 34
S423
R
R
K
H
R
R
S
S
K
P
I
K
R
P
V
Site 35
Y437
V
L
D
P
F
I
G
Y
D
E
D
S
M
D
S
Site 36
S441
F
I
G
Y
D
E
D
S
M
D
S
E
T
S
S
Site 37
S444
Y
D
E
D
S
M
D
S
E
T
S
S
M
A
S
Site 38
T446
E
D
S
M
D
S
E
T
S
S
M
A
S
F
R
Site 39
S448
S
M
D
S
E
T
S
S
M
A
S
F
R
T
D
Site 40
S451
S
E
T
S
S
M
A
S
F
R
T
D
R
T
P
Site 41
T457
A
S
F
R
T
D
R
T
P
A
T
P
D
D
D
Site 42
T460
R
T
D
R
T
P
A
T
P
D
D
D
L
D
E
Site 43
S468
P
D
D
D
L
D
E
S
L
A
A
E
E
S
E
Site 44
S474
E
S
L
A
A
E
E
S
E
L
R
F
R
Q
L
Site 45
T482
E
L
R
F
R
Q
L
T
K
E
Y
Q
A
L
Q
Site 46
Y492
Y
Q
A
L
Q
R
A
Y
A
L
L
Q
E
Q
T
Site 47
Y522
L
Q
A
E
V
L
R
Y
K
A
K
I
E
D
L
Site 48
S598
L
E
E
R
E
R
R
S
P
P
F
N
L
Q
I
Site 49
S609
N
L
Q
I
H
P
F
S
D
G
V
S
A
L
Q
Site 50
Y697
Q
F
C
K
I
K
G
Y
L
E
E
E
L
D
Y
Site 51
Y704
Y
L
E
E
E
L
D
Y
R
K
Q
A
L
D
Q
Site 52
Y713
K
Q
A
L
D
Q
A
Y
M
R
I
Q
E
L
E
Site 53
T722
R
I
Q
E
L
E
A
T
L
Y
N
A
L
Q
Q
Site 54
Y724
Q
E
L
E
A
T
L
Y
N
A
L
Q
Q
E
T
Site 55
T731
Y
N
A
L
Q
Q
E
T
V
I
K
F
G
E
L
Site 56
S740
I
K
F
G
E
L
L
S
E
K
Q
Q
E
E
L
Site 57
T749
K
Q
Q
E
E
L
R
T
A
V
E
K
L
R
R
Site 58
S762
R
R
Q
M
L
R
K
S
R
E
Y
D
C
Q
I
Site 59
Y765
M
L
R
K
S
R
E
Y
D
C
Q
I
L
Q
E
Site 60
T791
I
R
D
L
E
D
K
T
D
I
Q
K
R
Q
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation