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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FERMT2
Full Name:
Fermitin family homolog 2
Alias:
FERM2; fermitin family 2; KIND2; KIND2, MIG2, pleckstrin homology domain containing family C member 1; kindlin 2; kindlin-2; Mig-2; mitogen-inducible gene 2 protein; PKC1; PKHC1; PLEKHC1; UNC112B
Type:
Cytoskeletal protein
Mass (Da):
77861
Number AA:
680
UniProt ID:
Q96AC1
International Prot ID:
IPI00000856
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005938
GO:0005925
GO:0001725
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0030036
GO:0007155
GO:0008360
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y13
I
R
M
P
D
G
C
Y
A
D
G
T
W
E
L
Site 2
S21
A
D
G
T
W
E
L
S
V
H
V
T
D
L
N
Site 3
T25
W
E
L
S
V
H
V
T
D
L
N
R
D
V
T
Site 4
T32
T
D
L
N
R
D
V
T
L
R
V
T
G
E
V
Site 5
T36
R
D
V
T
L
R
V
T
G
E
V
H
I
G
G
Site 6
S59
L
D
V
K
K
D
W
S
D
H
A
L
W
W
E
Site 7
Y82
T
H
W
T
L
D
K
Y
G
I
Q
A
D
A
K
Site 8
T93
A
D
A
K
L
Q
F
T
P
Q
H
K
L
L
R
Site 9
Y108
L
Q
L
P
N
M
K
Y
V
K
V
K
V
N
F
Site 10
T129
A
V
S
D
I
C
K
T
F
N
I
R
H
P
E
Site 11
S139
I
R
H
P
E
E
L
S
L
L
K
K
P
R
D
Site 12
T148
L
K
K
P
R
D
P
T
K
K
K
K
K
K
L
Site 13
S159
K
K
K
L
D
D
Q
S
E
D
E
A
L
E
L
Site 14
T172
E
L
E
G
P
L
I
T
P
G
S
G
S
I
Y
Site 15
S175
G
P
L
I
T
P
G
S
G
S
I
Y
S
S
P
Site 16
S177
L
I
T
P
G
S
G
S
I
Y
S
S
P
G
L
Site 17
Y179
T
P
G
S
G
S
I
Y
S
S
P
G
L
Y
S
Site 18
S180
P
G
S
G
S
I
Y
S
S
P
G
L
Y
S
K
Site 19
S181
G
S
G
S
I
Y
S
S
P
G
L
Y
S
K
T
Site 20
Y185
I
Y
S
S
P
G
L
Y
S
K
T
M
T
P
T
Site 21
S186
Y
S
S
P
G
L
Y
S
K
T
M
T
P
T
Y
Site 22
T188
S
P
G
L
Y
S
K
T
M
T
P
T
Y
D
A
Site 23
T190
G
L
Y
S
K
T
M
T
P
T
Y
D
A
H
D
Site 24
Y193
S
K
T
M
T
P
T
Y
D
A
H
D
G
S
P
Site 25
S199
T
Y
D
A
H
D
G
S
P
L
S
P
T
S
A
Site 26
S202
A
H
D
G
S
P
L
S
P
T
S
A
W
F
G
Site 27
T204
D
G
S
P
L
S
P
T
S
A
W
F
G
D
S
Site 28
S205
G
S
P
L
S
P
T
S
A
W
F
G
D
S
A
Site 29
S211
T
S
A
W
F
G
D
S
A
L
S
E
G
N
P
Site 30
S214
W
F
G
D
S
A
L
S
E
G
N
P
G
I
L
Site 31
S224
N
P
G
I
L
A
V
S
Q
P
I
T
S
P
E
Site 32
S255
I
N
Q
G
W
L
D
S
S
R
S
L
M
E
Q
Site 33
S258
G
W
L
D
S
S
R
S
L
M
E
Q
D
V
K
Site 34
S278
L
L
R
F
K
Y
Y
S
F
F
D
L
N
P
K
Site 35
Y286
F
F
D
L
N
P
K
Y
D
A
I
R
I
N
Q
Site 36
Y295
A
I
R
I
N
Q
L
Y
E
Q
A
K
W
A
I
Site 37
S328
Q
Y
H
I
N
K
L
S
I
M
T
S
E
N
H
Site 38
S332
N
K
L
S
I
M
T
S
E
N
H
L
N
N
S
Site 39
S339
S
E
N
H
L
N
N
S
D
K
E
V
D
E
V
Site 40
S351
D
E
V
D
A
A
L
S
D
L
E
I
T
L
E
Site 41
Y378
S
I
P
E
L
A
D
Y
I
K
V
F
K
P
K
Site 42
T388
V
F
K
P
K
K
L
T
L
K
G
Y
K
Q
Y
Site 43
Y392
K
K
L
T
L
K
G
Y
K
Q
Y
W
C
T
F
Site 44
Y395
T
L
K
G
Y
K
Q
Y
W
C
T
F
K
D
T
Site 45
S405
T
F
K
D
T
S
I
S
C
Y
K
S
K
E
E
Site 46
Y407
K
D
T
S
I
S
C
Y
K
S
K
E
E
S
S
Site 47
S409
T
S
I
S
C
Y
K
S
K
E
E
S
S
G
T
Site 48
T416
S
K
E
E
S
S
G
T
P
A
H
Q
M
N
L
Site 49
T429
N
L
R
G
C
E
V
T
P
D
V
N
I
S
G
Site 50
S475
M
A
A
C
R
L
A
S
K
G
K
T
M
A
D
Site 51
T479
R
L
A
S
K
G
K
T
M
A
D
S
S
Y
N
Site 52
S483
K
G
K
T
M
A
D
S
S
Y
N
L
E
V
Q
Site 53
S484
G
K
T
M
A
D
S
S
Y
N
L
E
V
Q
N
Site 54
Y485
K
T
M
A
D
S
S
Y
N
L
E
V
Q
N
I
Site 55
T517
E
Q
I
T
T
D
I
T
P
E
C
L
V
S
P
Site 56
S523
I
T
P
E
C
L
V
S
P
R
Y
L
K
K
Y
Site 57
Y526
E
C
L
V
S
P
R
Y
L
K
K
Y
K
N
K
Site 58
Y530
S
P
R
Y
L
K
K
Y
K
N
K
Q
I
T
A
Site 59
T536
K
Y
K
N
K
Q
I
T
A
R
I
L
E
A
H
Site 60
S564
R
F
I
Q
A
W
Q
S
L
P
E
F
G
I
T
Site 61
Y590
E
E
L
I
G
I
A
Y
N
R
L
I
R
M
D
Site 62
T600
L
I
R
M
D
A
S
T
G
D
A
I
K
T
W
Site 63
T606
S
T
G
D
A
I
K
T
W
R
F
S
N
M
K
Site 64
S657
I
G
G
Y
I
F
L
S
T
R
A
K
D
Q
N
Site 65
S666
R
A
K
D
Q
N
E
S
L
D
E
E
M
F
Y
Site 66
Y673
S
L
D
E
E
M
F
Y
K
L
T
S
G
W
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation