PhosphoNET

           
Protein Info 
   
Short Name:  ACD
Full Name:  Adrenocortical dysplasia protein homolog
Alias:  PIP1; POT1 and TIN2 organizing; POT1 and TIN2-interacting; PTOP; TIN2 interacting 1; TINT1
Type:  Adaptor/scaffold
Mass (Da):  57758
Number AA:  544
UniProt ID:  Q96AP0
International Prot ID:  IPI00254484
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0000783  GO:0005654  GO:0000783 Uniprot OncoNet
Molecular Function:  GO:0003677  GO:0070182  GO:0005488 PhosphoSite+ KinaseNET
Biological Process:  GO:0006886  GO:0032211  GO:0060381 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S18MRVNGPASRAPAGWT
Site 2S26RAPAGWTSGSLHTGP
Site 3S28PAGWTSGSLHTGPRA
Site 4S106IRELILGSETPSSPR
Site 5T108ELILGSETPSSPRAG
Site 6S110ILGSETPSSPRAGQL
Site 7S111LGSETPSSPRAGQLL
Site 8S132EAAVAGPSHAPDTSD
Site 9T137GPSHAPDTSDVGATL
Site 10S138PSHAPDTSDVGATLL
Site 11T164VTREALDTSDWEEKE
Site 12S165TREALDTSDWEEKEF
Site 13T177KEFGFRGTEGRLLLL
Site 14Y203GGAPAEFYLQVDRFS
Site 15S210YLQVDRFSLLPTEQP
Site 16T214DRFSLLPTEQPRLRV
Site 17Y235LDVQKKLYDCLEEHL
Site 18S243DCLEEHLSESTSSNA
Site 19S245LEEHLSESTSSNAGL
Site 20S247EHLSESTSSNAGLSL
Site 21S248HLSESTSSNAGLSLS
Site 22S253TSSNAGLSLSQLLDE
Site 23S255SNAGLSLSQLLDEMR
Site 24T291PCTAPPVTHWAASRC
Site 25S324ENDQLILSSLGPCQR
Site 26S325NDQLILSSLGPCQRT
Site 27T332SLGPCQRTQGPELPP
Site 28S357TLIASPPSSPSSSGT
Site 29S358LIASPPSSPSSSGTP
Site 30S360ASPPSSPSSSGTPAL
Site 31S361SPPSSPSSSGTPALP
Site 32S362PPSSPSSSGTPALPG
Site 33T364SSPSSSGTPALPGHM
Site 34S372PALPGHMSSEESGTS
Site 35S373ALPGHMSSEESGTSI
Site 36S376GHMSSEESGTSISLL
Site 37T378MSSEESGTSISLLPA
Site 38S379SSEESGTSISLLPAL
Site 39S397APDPGQRSSSQPSPA
Site 40S398PDPGQRSSSQPSPAI
Site 41S399DPGQRSSSQPSPAIC
Site 42S402QRSSSQPSPAICSAP
Site 43S407QPSPAICSAPATLTP
Site 44T411AICSAPATLTPRSPH
Site 45T413CSAPATLTPRSPHAS
Site 46S416PATLTPRSPHASRTP
Site 47S420TPRSPHASRTPSSPL
Site 48T422RSPHASRTPSSPLQS
Site 49S424PHASRTPSSPLQSCT
Site 50S425HASRTPSSPLQSCTP
Site 51S429TPSSPLQSCTPSLSP
Site 52T431SSPLQSCTPSLSPRS
Site 53S433PLQSCTPSLSPRSHV
Site 54S435QSCTPSLSPRSHVPS
Site 55S438TPSLSPRSHVPSPHQ
Site 56S442SPRSHVPSPHQALVT
Site 57T449SPHQALVTRPQKPSL
Site 58S455VTRPQKPSLEFKEFV
Site 59T475NRPPFPRTGATRGAQ
Site 60S486RGAQEPCSVWEPPKR
Site 61S498PKRHRDGSAFQYEYE
Site 62Y502RDGSAFQYEYEPPCT
Site 63Y504GSAFQYEYEPPCTSL
Site 64T509YEYEPPCTSLCARVQ
Site 65S510EYEPPCTSLCARVQA
Site 66S539LMDAQPGSEPTPM__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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