KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
E2F7
Full Name:
Transcription factor E2F7
Alias:
E2F transcription factor 7; E2F-7
Type:
Mass (Da):
99845
Number AA:
911
UniProt ID:
Q96AV8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005667
Uniprot
OncoNet
Molecular Function:
GO:0042802
PhosphoSite+
KinaseNET
Biological Process:
GO:0007049
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
L
T
L
K
D
L
I
S
P
R
Q
P
R
L
D
Site 2
T45
R
S
R
M
A
P
K
T
P
I
K
N
E
P
I
Site 3
S55
K
N
E
P
I
D
L
S
K
Q
K
K
F
T
P
Site 4
T61
L
S
K
Q
K
K
F
T
P
E
R
N
P
I
T
Site 5
T68
T
P
E
R
N
P
I
T
P
V
K
L
V
D
R
Site 6
T82
R
Q
Q
A
E
P
W
T
P
T
A
N
L
K
M
Site 7
T84
Q
A
E
P
W
T
P
T
A
N
L
K
M
L
I
Site 8
S95
K
M
L
I
S
A
A
S
P
D
I
R
D
R
E
Site 9
T119
E
N
K
D
D
A
F
T
D
S
L
Q
L
D
V
Site 10
S121
K
D
D
A
F
T
D
S
L
Q
L
D
V
V
G
Site 11
S130
Q
L
D
V
V
G
D
S
A
V
D
E
F
E
K
Site 12
S141
E
F
E
K
Q
R
P
S
R
K
Q
K
S
L
G
Site 13
S146
R
P
S
R
K
Q
K
S
L
G
L
L
C
Q
K
Site 14
Y158
C
Q
K
F
L
A
R
Y
P
S
Y
P
L
S
T
Site 15
S160
K
F
L
A
R
Y
P
S
Y
P
L
S
T
E
K
Site 16
Y161
F
L
A
R
Y
P
S
Y
P
L
S
T
E
K
T
Site 17
S164
R
Y
P
S
Y
P
L
S
T
E
K
T
T
I
S
Site 18
T168
Y
P
L
S
T
E
K
T
T
I
S
L
D
E
V
Site 19
S171
S
T
E
K
T
T
I
S
L
D
E
V
A
V
S
Site 20
S178
S
L
D
E
V
A
V
S
L
G
V
E
R
R
R
Site 21
Y187
G
V
E
R
R
R
I
Y
D
I
V
N
V
L
E
Site 22
Y207
S
R
V
A
K
N
Q
Y
G
W
H
G
R
H
S
Site 23
S214
Y
G
W
H
G
R
H
S
L
P
K
T
L
R
N
Site 24
T218
G
R
H
S
L
P
K
T
L
R
N
L
Q
R
L
Site 25
Y231
R
L
G
E
E
Q
K
Y
E
E
Q
M
A
Y
L
Site 26
Y237
K
Y
E
E
Q
M
A
Y
L
Q
Q
K
E
L
D
Site 27
Y248
K
E
L
D
L
I
D
Y
K
F
G
E
R
K
K
Site 28
S261
K
K
D
G
D
P
D
S
Q
E
Q
Q
L
L
D
Site 29
S270
E
Q
Q
L
L
D
F
S
E
P
D
C
P
S
S
Site 30
S276
F
S
E
P
D
C
P
S
S
S
A
N
S
R
K
Site 31
S277
S
E
P
D
C
P
S
S
S
A
N
S
R
K
D
Site 32
S278
E
P
D
C
P
S
S
S
A
N
S
R
K
D
K
Site 33
S281
C
P
S
S
S
A
N
S
R
K
D
K
S
L
R
Site 34
S286
A
N
S
R
K
D
K
S
L
R
I
M
S
Q
K
Site 35
S319
A
K
I
L
I
E
E
S
Q
D
A
P
D
H
S
Site 36
S326
S
Q
D
A
P
D
H
S
K
F
K
T
K
V
R
Site 37
T330
P
D
H
S
K
F
K
T
K
V
R
R
L
Y
D
Site 38
Y336
K
T
K
V
R
R
L
Y
D
I
A
N
V
L
T
Site 39
S373
I
G
P
V
D
F
S
S
S
D
E
E
L
V
D
Site 40
S374
G
P
V
D
F
S
S
S
D
E
E
L
V
D
V
Site 41
T393
L
P
E
L
K
R
E
T
Y
G
Q
I
Q
V
C
Site 42
Y394
P
E
L
K
R
E
T
Y
G
Q
I
Q
V
C
A
Site 43
S410
Q
K
L
A
R
H
G
S
F
N
T
V
Q
A
S
Site 44
T413
A
R
H
G
S
F
N
T
V
Q
A
S
E
R
I
Site 45
S417
S
F
N
T
V
Q
A
S
E
R
I
Q
R
K
V
Site 46
S426
R
I
Q
R
K
V
N
S
E
P
S
S
P
Y
R
Site 47
S430
K
V
N
S
E
P
S
S
P
Y
R
E
E
Q
G
Site 48
S438
P
Y
R
E
E
Q
G
S
G
G
Y
S
L
E
I
Site 49
S442
E
Q
G
S
G
G
Y
S
L
E
I
G
S
L
A
Site 50
S460
R
Q
K
I
E
D
N
S
Q
G
K
A
F
A
S
Site 51
S467
S
Q
G
K
A
F
A
S
K
R
V
V
P
P
S
Site 52
S474
S
K
R
V
V
P
P
S
S
S
L
D
P
V
A
Site 53
S475
K
R
V
V
P
P
S
S
S
L
D
P
V
A
P
Site 54
S513
Q
T
D
L
Q
A
F
S
M
Q
N
G
L
N
G
Site 55
S567
S
L
Q
E
G
P
A
S
G
S
G
S
E
R
D
Site 56
S571
G
P
A
S
G
S
G
S
E
R
D
D
R
S
S
Site 57
S577
G
S
E
R
D
D
R
S
S
E
A
P
A
T
V
Site 58
S578
S
E
R
D
D
R
S
S
E
A
P
A
T
V
E
Site 59
T583
R
S
S
E
A
P
A
T
V
E
L
S
S
A
P
Site 60
S587
A
P
A
T
V
E
L
S
S
A
P
S
A
Q
K
Site 61
S588
P
A
T
V
E
L
S
S
A
P
S
A
Q
K
R
Site 62
S591
V
E
L
S
S
A
P
S
A
Q
K
R
L
C
E
Site 63
T610
Q
E
E
D
E
P
A
T
K
R
Q
S
R
E
Y
Site 64
S614
E
P
A
T
K
R
Q
S
R
E
Y
E
D
G
P
Site 65
Y617
T
K
R
Q
S
R
E
Y
E
D
G
P
L
S
L
Site 66
S623
E
Y
E
D
G
P
L
S
L
V
M
P
K
K
P
Site 67
S631
L
V
M
P
K
K
P
S
D
S
T
D
L
A
S
Site 68
S633
M
P
K
K
P
S
D
S
T
D
L
A
S
P
K
Site 69
T634
P
K
K
P
S
D
S
T
D
L
A
S
P
K
T
Site 70
S638
S
D
S
T
D
L
A
S
P
K
T
M
G
N
R
Site 71
T641
T
D
L
A
S
P
K
T
M
G
N
R
A
S
I
Site 72
S647
K
T
M
G
N
R
A
S
I
P
L
K
D
I
H
Site 73
T670
E
E
I
S
G
K
A
T
A
N
S
L
V
S
S
Site 74
S673
S
G
K
A
T
A
N
S
L
V
S
S
E
W
G
Site 75
S677
T
A
N
S
L
V
S
S
E
W
G
N
P
S
R
Site 76
T686
W
G
N
P
S
R
N
T
D
V
E
K
P
S
K
Site 77
S692
N
T
D
V
E
K
P
S
K
E
N
E
S
T
K
Site 78
T698
P
S
K
E
N
E
S
T
K
E
P
S
L
L
Q
Site 79
S702
N
E
S
T
K
E
P
S
L
L
Q
Y
L
C
V
Site 80
Y706
K
E
P
S
L
L
Q
Y
L
C
V
Q
S
P
A
Site 81
S723
N
G
F
N
V
L
L
S
G
S
Q
T
P
P
T
Site 82
T730
S
G
S
Q
T
P
P
T
V
G
P
S
S
G
Q
Site 83
S734
T
P
P
T
V
G
P
S
S
G
Q
L
P
S
F
Site 84
S735
P
P
T
V
G
P
S
S
G
Q
L
P
S
F
S
Site 85
S806
T
A
V
V
N
P
K
S
S
T
L
P
S
A
D
Site 86
S807
A
V
V
N
P
K
S
S
T
L
P
S
A
D
P
Site 87
S811
P
K
S
S
T
L
P
S
A
D
P
Q
L
Q
S
Site 88
S818
S
A
D
P
Q
L
Q
S
Q
P
S
L
N
L
S
Site 89
S821
P
Q
L
Q
S
Q
P
S
L
N
L
S
P
V
M
Site 90
S825
S
Q
P
S
L
N
L
S
P
V
M
S
R
S
H
Site 91
S829
L
N
L
S
P
V
M
S
R
S
H
S
V
V
Q
Site 92
S831
L
S
P
V
M
S
R
S
H
S
V
V
Q
Q
P
Site 93
S833
P
V
M
S
R
S
H
S
V
V
Q
Q
P
E
S
Site 94
S840
S
V
V
Q
Q
P
E
S
P
V
Y
V
G
H
P
Site 95
Y843
Q
Q
P
E
S
P
V
Y
V
G
H
P
V
S
V
Site 96
S856
S
V
V
K
L
Q
Q
S
P
V
P
V
T
P
K
Site 97
T861
Q
Q
S
P
V
P
V
T
P
K
S
I
Q
R
T
Site 98
S864
P
V
P
V
T
P
K
S
I
Q
R
T
H
R
E
Site 99
T868
T
P
K
S
I
Q
R
T
H
R
E
T
F
F
K
Site 100
T872
I
Q
R
T
H
R
E
T
F
F
K
T
P
G
S
Site 101
T876
H
R
E
T
F
F
K
T
P
G
S
L
G
D
P
Site 102
S879
T
F
F
K
T
P
G
S
L
G
D
P
V
L
K
Site 103
S893
K
R
R
E
R
N
Q
S
R
N
T
S
S
A
Q
Site 104
T896
E
R
N
Q
S
R
N
T
S
S
A
Q
R
R
L
Site 105
S897
R
N
Q
S
R
N
T
S
S
A
Q
R
R
L
E
Site 106
S898
N
Q
S
R
N
T
S
S
A
Q
R
R
L
E
I
Site 107
S907
Q
R
R
L
E
I
P
S
G
G
A
D
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation