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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FKBP10
Full Name:
Peptidyl-prolyl cis-trans isomerase FKBP10
Alias:
65 kDa FK506-binding protein;FK506-binding protein 10;Immunophilin FKBP65;Rotamase
Type:
Mass (Da):
64245
Number AA:
582
UniProt ID:
Q96AY3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
F
P
A
G
P
P
S
H
S
L
L
R
L
P
Site 2
S35
G
R
G
L
G
R
A
S
P
A
G
G
P
L
E
Site 3
Y49
E
D
V
V
I
E
R
Y
H
I
P
R
A
C
P
Site 4
Y67
Q
M
G
D
F
V
R
Y
H
Y
N
G
T
F
E
Site 5
Y69
G
D
F
V
R
Y
H
Y
N
G
T
F
E
D
G
Site 6
T72
V
R
Y
H
Y
N
G
T
F
E
D
G
K
K
F
Site 7
S81
E
D
G
K
K
F
D
S
S
Y
D
R
N
T
L
Site 8
S82
D
G
K
K
F
D
S
S
Y
D
R
N
T
L
V
Site 9
Y83
G
K
K
F
D
S
S
Y
D
R
N
T
L
V
A
Site 10
T155
D
V
W
N
K
E
D
T
V
Q
V
S
T
L
L
Site 11
T160
E
D
T
V
Q
V
S
T
L
L
R
P
P
H
C
Site 12
Y179
Q
D
G
D
F
V
R
Y
H
Y
N
G
T
L
L
Site 13
Y181
G
D
F
V
R
Y
H
Y
N
G
T
L
L
D
G
Site 14
T184
V
R
Y
H
Y
N
G
T
L
L
D
G
T
S
F
Site 15
T189
N
G
T
L
L
D
G
T
S
F
D
T
S
Y
S
Site 16
S190
G
T
L
L
D
G
T
S
F
D
T
S
Y
S
K
Site 17
T193
L
D
G
T
S
F
D
T
S
Y
S
K
G
G
T
Site 18
S194
D
G
T
S
F
D
T
S
Y
S
K
G
G
T
Y
Site 19
Y195
G
T
S
F
D
T
S
Y
S
K
G
G
T
Y
D
Site 20
T200
T
S
Y
S
K
G
G
T
Y
D
T
Y
V
G
S
Site 21
Y201
S
Y
S
K
G
G
T
Y
D
T
Y
V
G
S
G
Site 22
T203
S
K
G
G
T
Y
D
T
Y
V
G
S
G
W
L
Site 23
Y204
K
G
G
T
Y
D
T
Y
V
G
S
G
W
L
I
Site 24
Y242
L
A
Y
G
E
K
G
Y
G
T
V
I
P
P
Q
Site 25
T244
Y
G
E
K
G
Y
G
T
V
I
P
P
Q
A
S
Site 26
Y291
G
A
G
D
F
M
R
Y
H
Y
N
G
S
L
M
Site 27
Y293
G
D
F
M
R
Y
H
Y
N
G
S
L
M
D
G
Site 28
T301
N
G
S
L
M
D
G
T
L
F
D
S
S
Y
S
Site 29
S305
M
D
G
T
L
F
D
S
S
Y
S
R
N
H
T
Site 30
S306
D
G
T
L
F
D
S
S
Y
S
R
N
H
T
Y
Site 31
Y307
G
T
L
F
D
S
S
Y
S
R
N
H
T
Y
N
Site 32
T312
S
S
Y
S
R
N
H
T
Y
N
T
Y
I
G
Q
Site 33
Y313
S
Y
S
R
N
H
T
Y
N
T
Y
I
G
Q
G
Site 34
Y316
R
N
H
T
Y
N
T
Y
I
G
Q
G
Y
I
I
Site 35
Y321
N
T
Y
I
G
Q
G
Y
I
I
P
G
M
D
Q
Site 36
T342
M
G
E
R
R
R
I
T
I
P
P
H
L
A
Y
Site 37
Y349
T
I
P
P
H
L
A
Y
G
E
N
G
T
G
D
Site 38
S386
V
V
E
I
R
T
L
S
R
P
S
E
T
C
N
Site 39
S389
I
R
T
L
S
R
P
S
E
T
C
N
E
T
T
Site 40
Y404
K
L
G
D
F
V
R
Y
H
Y
N
C
S
L
L
Site 41
Y406
G
D
F
V
R
Y
H
Y
N
C
S
L
L
D
G
Site 42
T414
N
C
S
L
L
D
G
T
Q
L
F
T
S
H
D
Site 43
S419
D
G
T
Q
L
F
T
S
H
D
Y
G
A
P
Q
Site 44
Y422
Q
L
F
T
S
H
D
Y
G
A
P
Q
E
A
T
Site 45
S465
P
H
L
A
H
G
E
S
G
A
R
G
V
P
G
Site 46
S484
L
F
E
V
E
L
V
S
R
E
D
G
L
P
T
Site 47
Y493
E
D
G
L
P
T
G
Y
L
F
V
W
H
K
D
Site 48
T524
V
P
P
E
E
F
S
T
F
I
K
A
Q
V
S
Site 49
S531
T
F
I
K
A
Q
V
S
E
G
K
G
R
L
M
Site 50
T546
P
G
Q
D
P
E
K
T
I
G
D
M
F
Q
N
Site 51
S571
V
D
E
L
K
L
K
S
D
E
D
E
E
R
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation