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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Dact3
Full Name:
Dapper homolog 3
Alias:
Antagonist of beta-catenin Dapper 3; Antagonist of beta-catenin Dapper homolog 3; Arginine-rich region 1; Arginine-rich region 1 protein; Dapper, antagonist of beta-catenin, 3; MGC15476; RRR1; Thymus expressed gene 3-like
Type:
Unknown function
Mass (Da):
64931
Number AA:
629
UniProt ID:
Q96B18
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
I
R
A
F
S
F
P
V
S
P
E
R
Site 2
S10
R
A
F
S
F
P
V
S
P
E
R
G
R
L
R
Site 3
Y39
W
L
R
E
R
Q
E
Y
R
V
Q
Q
A
L
R
Site 4
S101
G
Q
Q
L
G
D
L
S
L
E
S
G
G
L
E
Site 5
S111
S
G
G
L
E
Q
E
S
G
R
S
S
G
F
Y
Site 6
S115
E
Q
E
S
G
R
S
S
G
F
Y
E
D
P
S
Site 7
Y118
S
G
R
S
S
G
F
Y
E
D
P
S
S
T
G
Site 8
S122
S
G
F
Y
E
D
P
S
S
T
G
G
P
D
S
Site 9
S123
G
F
Y
E
D
P
S
S
T
G
G
P
D
S
P
Site 10
S129
S
S
T
G
G
P
D
S
P
P
S
T
F
C
G
Site 11
S132
G
G
P
D
S
P
P
S
T
F
C
G
D
S
G
Site 12
T133
G
P
D
S
P
P
S
T
F
C
G
D
S
G
F
Site 13
S138
P
S
T
F
C
G
D
S
G
F
S
G
S
S
S
Site 14
S141
F
C
G
D
S
G
F
S
G
S
S
S
Y
G
R
Site 15
S143
G
D
S
G
F
S
G
S
S
S
Y
G
R
L
G
Site 16
S144
D
S
G
F
S
G
S
S
S
Y
G
R
L
G
P
Site 17
S145
S
G
F
S
G
S
S
S
Y
G
R
L
G
P
S
Site 18
Y146
G
F
S
G
S
S
S
Y
G
R
L
G
P
S
E
Site 19
S152
S
Y
G
R
L
G
P
S
E
P
R
G
I
Y
A
Site 20
Y158
P
S
E
P
R
G
I
Y
A
S
E
R
P
K
S
Site 21
S160
E
P
R
G
I
Y
A
S
E
R
P
K
S
L
G
Site 22
S165
Y
A
S
E
R
P
K
S
L
G
D
A
S
P
S
Site 23
S170
P
K
S
L
G
D
A
S
P
S
A
P
E
V
V
Site 24
S186
A
R
A
A
V
P
R
S
F
S
A
P
Y
P
T
Site 25
S188
A
A
V
P
R
S
F
S
A
P
Y
P
T
A
G
Site 26
Y191
P
R
S
F
S
A
P
Y
P
T
A
G
G
S
A
Site 27
T193
S
F
S
A
P
Y
P
T
A
G
G
S
A
G
P
Site 28
S197
P
Y
P
T
A
G
G
S
A
G
P
E
A
C
S
Site 29
S204
S
A
G
P
E
A
C
S
S
A
E
R
R
A
R
Site 30
S205
A
G
P
E
A
C
S
S
A
E
R
R
A
R
A
Site 31
S228
L
H
A
V
A
M
R
S
P
R
P
C
G
R
P
Site 32
T237
R
P
C
G
R
P
P
T
D
S
P
D
A
G
G
Site 33
S239
C
G
R
P
P
T
D
S
P
D
A
G
G
A
G
Site 34
Y252
A
G
R
P
L
D
G
Y
I
S
A
L
L
R
R
Site 35
T270
R
G
A
G
Q
P
R
T
S
P
G
G
A
D
G
Site 36
S271
G
A
G
Q
P
R
T
S
P
G
G
A
D
G
G
Site 37
S284
G
G
P
R
R
Q
N
S
V
R
Q
R
P
P
D
Site 38
S293
R
Q
R
P
P
D
A
S
P
S
P
G
S
A
R
Site 39
S295
R
P
P
D
A
S
P
S
P
G
S
A
R
P
A
Site 40
S298
D
A
S
P
S
P
G
S
A
R
P
A
R
E
P
Site 41
S306
A
R
P
A
R
E
P
S
L
E
R
V
G
G
H
Site 42
T315
E
R
V
G
G
H
P
T
S
P
A
A
L
S
R
Site 43
S316
R
V
G
G
H
P
T
S
P
A
A
L
S
R
A
Site 44
S321
P
T
S
P
A
A
L
S
R
A
W
A
S
S
W
Site 45
S326
A
L
S
R
A
W
A
S
S
W
E
S
E
A
A
Site 46
S327
L
S
R
A
W
A
S
S
W
E
S
E
A
A
P
Site 47
S330
A
W
A
S
S
W
E
S
E
A
A
P
E
P
A
Site 48
S344
A
A
P
P
A
A
P
S
P
P
D
S
P
A
E
Site 49
S348
A
A
P
S
P
P
D
S
P
A
E
G
R
L
V
Site 50
T383
R
R
K
P
P
P
L
T
R
G
R
S
V
E
Q
Site 51
S387
P
P
L
T
R
G
R
S
V
E
Q
S
P
P
R
Site 52
S391
R
G
R
S
V
E
Q
S
P
P
R
E
R
P
R
Site 53
S410
R
G
R
M
A
E
A
S
G
R
R
G
S
P
R
Site 54
S415
E
A
S
G
R
R
G
S
P
R
A
R
K
A
S
Site 55
S422
S
P
R
A
R
K
A
S
R
S
Q
S
E
T
S
Site 56
S424
R
A
R
K
A
S
R
S
Q
S
E
T
S
L
L
Site 57
S426
R
K
A
S
R
S
Q
S
E
T
S
L
L
G
R
Site 58
T428
A
S
R
S
Q
S
E
T
S
L
L
G
R
A
S
Site 59
S429
S
R
S
Q
S
E
T
S
L
L
G
R
A
S
A
Site 60
S435
T
S
L
L
G
R
A
S
A
V
P
S
G
P
P
Site 61
S439
G
R
A
S
A
V
P
S
G
P
P
K
Y
P
T
Site 62
Y444
V
P
S
G
P
P
K
Y
P
T
A
E
R
E
E
Site 63
T446
S
G
P
P
K
Y
P
T
A
E
R
E
E
P
R
Site 64
T464
P
R
R
G
P
A
P
T
L
A
A
Q
A
A
G
Site 65
S472
L
A
A
Q
A
A
G
S
C
R
R
W
R
S
T
Site 66
S478
G
S
C
R
R
W
R
S
T
A
E
I
D
A
A
Site 67
T479
S
C
R
R
W
R
S
T
A
E
I
D
A
A
D
Site 68
S505
R
V
P
G
P
G
P
S
P
S
A
P
Q
R
R
Site 69
S507
P
G
P
G
P
S
P
S
A
P
Q
R
R
L
L
Site 70
Y515
A
P
Q
R
R
L
L
Y
G
C
A
G
S
D
S
Site 71
S520
L
L
Y
G
C
A
G
S
D
S
E
C
S
A
G
Site 72
S522
Y
G
C
A
G
S
D
S
E
C
S
A
G
R
L
Site 73
S525
A
G
S
D
S
E
C
S
A
G
R
L
G
P
L
Site 74
Y545
A
G
G
V
G
G
G
Y
G
E
S
E
S
S
A
Site 75
S548
V
G
G
G
Y
G
E
S
E
S
S
A
S
E
G
Site 76
S550
G
G
Y
G
E
S
E
S
S
A
S
E
G
E
S
Site 77
S551
G
Y
G
E
S
E
S
S
A
S
E
G
E
S
P
Site 78
S553
G
E
S
E
S
S
A
S
E
G
E
S
P
A
F
Site 79
S557
S
S
A
S
E
G
E
S
P
A
F
S
S
A
S
Site 80
S561
E
G
E
S
P
A
F
S
S
A
S
S
D
S
D
Site 81
S562
G
E
S
P
A
F
S
S
A
S
S
D
S
D
G
Site 82
S564
S
P
A
F
S
S
A
S
S
D
S
D
G
S
G
Site 83
S565
P
A
F
S
S
A
S
S
D
S
D
G
S
G
G
Site 84
S567
F
S
S
A
S
S
D
S
D
G
S
G
G
L
V
Site 85
S570
A
S
S
D
S
D
G
S
G
G
L
V
W
P
Q
Site 86
S620
K
K
I
L
R
F
R
S
G
S
L
K
V
M
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation