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Updated November 2019
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Protein Info
Short Name:
C18orf25
Full Name:
Uncharacterized protein C18orf25
Alias:
ARKadia-like 1; ARKL1; Chromosome 18 open reading frame 25; CR025; MGC12909
Type:
Unknown function
Mass (Da):
43324
Number AA:
403
UniProt ID:
Q96B23
International Prot ID:
IPI00059687
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
K
V
E
E
L
I
E
S
E
A
P
P
K
A
S
Site 2
S34
T
A
K
E
E
D
G
S
V
E
L
E
S
Q
V
Site 3
S39
D
G
S
V
E
L
E
S
Q
V
Q
K
D
G
V
Site 4
S49
Q
K
D
G
V
A
D
S
T
V
I
S
S
M
P
Site 5
S66
L
M
E
L
R
R
D
S
S
E
S
Q
L
A
S
Site 6
S67
M
E
L
R
R
D
S
S
E
S
Q
L
A
S
T
Site 7
S69
L
R
R
D
S
S
E
S
Q
L
A
S
T
E
S
Site 8
S73
S
S
E
S
Q
L
A
S
T
E
S
D
K
P
T
Site 9
T74
S
E
S
Q
L
A
S
T
E
S
D
K
P
T
T
Site 10
S76
S
Q
L
A
S
T
E
S
D
K
P
T
T
G
R
Site 11
T80
S
T
E
S
D
K
P
T
T
G
R
V
Y
E
S
Site 12
T81
T
E
S
D
K
P
T
T
G
R
V
Y
E
S
D
Site 13
Y85
K
P
T
T
G
R
V
Y
E
S
D
S
S
N
H
Site 14
S87
T
T
G
R
V
Y
E
S
D
S
S
N
H
C
M
Site 15
S89
G
R
V
Y
E
S
D
S
S
N
H
C
M
L
S
Site 16
S90
R
V
Y
E
S
D
S
S
N
H
C
M
L
S
P
Site 17
S96
S
S
N
H
C
M
L
S
P
S
S
S
G
H
L
Site 18
S98
N
H
C
M
L
S
P
S
S
S
G
H
L
A
D
Site 19
S100
C
M
L
S
P
S
S
S
G
H
L
A
D
S
D
Site 20
S106
S
S
G
H
L
A
D
S
D
T
L
S
S
A
E
Site 21
T108
G
H
L
A
D
S
D
T
L
S
S
A
E
E
N
Site 22
S110
L
A
D
S
D
T
L
S
S
A
E
E
N
E
P
Site 23
S118
S
A
E
E
N
E
P
S
Q
A
E
T
A
V
E
Site 24
S132
E
G
D
P
S
G
V
S
G
A
T
V
G
R
K
Site 25
T135
P
S
G
V
S
G
A
T
V
G
R
K
S
R
R
Site 26
S140
G
A
T
V
G
R
K
S
R
R
S
R
S
E
S
Site 27
S143
V
G
R
K
S
R
R
S
R
S
E
S
E
T
S
Site 28
S145
R
K
S
R
R
S
R
S
E
S
E
T
S
T
M
Site 29
S147
S
R
R
S
R
S
E
S
E
T
S
T
M
A
A
Site 30
T149
R
S
R
S
E
S
E
T
S
T
M
A
A
K
K
Site 31
T151
R
S
E
S
E
T
S
T
M
A
A
K
K
N
R
Site 32
S160
A
A
K
K
N
R
Q
S
S
D
K
Q
N
G
R
Site 33
S161
A
K
K
N
R
Q
S
S
D
K
Q
N
G
R
V
Site 34
S176
A
K
V
K
G
H
R
S
Q
K
H
K
E
R
I
Site 35
Y198
E
A
A
A
R
K
K
Y
N
L
L
Q
D
S
S
Site 36
S204
K
Y
N
L
L
Q
D
S
S
T
S
D
S
D
L
Site 37
S205
Y
N
L
L
Q
D
S
S
T
S
D
S
D
L
T
Site 38
T206
N
L
L
Q
D
S
S
T
S
D
S
D
L
T
C
Site 39
S207
L
L
Q
D
S
S
T
S
D
S
D
L
T
C
D
Site 40
S209
Q
D
S
S
T
S
D
S
D
L
T
C
D
S
S
Site 41
T212
S
T
S
D
S
D
L
T
C
D
S
S
T
S
S
Site 42
S215
D
S
D
L
T
C
D
S
S
T
S
S
S
D
D
Site 43
S216
S
D
L
T
C
D
S
S
T
S
S
S
D
D
D
Site 44
S219
T
C
D
S
S
T
S
S
S
D
D
D
E
E
V
Site 45
S220
C
D
S
S
T
S
S
S
D
D
D
E
E
V
S
Site 46
S227
S
D
D
D
E
E
V
S
G
S
S
K
T
I
T
Site 47
S229
D
D
E
E
V
S
G
S
S
K
T
I
T
A
E
Site 48
T234
S
G
S
S
K
T
I
T
A
E
I
P
D
G
P
Site 49
Y247
G
P
P
V
V
A
H
Y
D
M
S
D
T
N
S
Site 50
S250
V
V
A
H
Y
D
M
S
D
T
N
S
D
P
E
Site 51
T252
A
H
Y
D
M
S
D
T
N
S
D
P
E
V
V
Site 52
S254
Y
D
M
S
D
T
N
S
D
P
E
V
V
N
V
Site 53
S274
A
A
V
V
Q
E
H
S
N
S
V
G
G
Q
D
Site 54
S276
V
V
Q
E
H
S
N
S
V
G
G
Q
D
T
G
Site 55
T285
G
G
Q
D
T
G
A
T
W
R
T
S
G
L
L
Site 56
S289
T
G
A
T
W
R
T
S
G
L
L
E
E
L
N
Site 57
S309
L
D
P
G
F
L
A
S
D
K
T
S
G
N
A
Site 58
T312
G
F
L
A
S
D
K
T
S
G
N
A
P
L
N
Site 59
S313
F
L
A
S
D
K
T
S
G
N
A
P
L
N
E
Site 60
S326
N
E
E
I
N
I
A
S
S
D
S
E
V
E
I
Site 61
S327
E
E
I
N
I
A
S
S
D
S
E
V
E
I
V
Site 62
S329
I
N
I
A
S
S
D
S
E
V
E
I
V
G
V
Site 63
S352
P
R
G
G
V
I
Q
S
V
S
S
W
K
H
G
Site 64
S354
G
G
V
I
Q
S
V
S
S
W
K
H
G
S
G
Site 65
S355
G
G
V
I
Q
S
V
S
S
W
K
H
G
S
G
Site 66
S360
V
S
S
W
K
H
G
S
G
T
Q
Y
V
S
T
Site 67
T362
S
W
K
H
G
S
G
T
Q
Y
V
S
T
R
Q
Site 68
Y364
K
H
G
S
G
T
Q
Y
V
S
T
R
Q
T
Q
Site 69
S366
G
S
G
T
Q
Y
V
S
T
R
Q
T
Q
S
W
Site 70
T370
Q
Y
V
S
T
R
Q
T
Q
S
W
T
A
V
T
Site 71
S372
V
S
T
R
Q
T
Q
S
W
T
A
V
T
P
Q
Site 72
T377
T
Q
S
W
T
A
V
T
P
Q
Q
T
W
A
S
Site 73
S384
T
P
Q
Q
T
W
A
S
P
A
E
V
V
D
L
Site 74
T392
P
A
E
V
V
D
L
T
L
D
E
D
S
R
R
Site 75
S397
D
L
T
L
D
E
D
S
R
R
K
Y
L
L
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation