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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ARRDC3
Full Name:
Arrestin domain-containing protein 3
Alias:
ARRD3; Arrestin domain containing 3
Type:
Uncharacterized protein
Mass (Da):
46395
Number AA:
414
UniProt ID:
Q96B67
International Prot ID:
IPI00002205
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
K
V
K
S
L
T
I
S
F
D
C
L
N
D
S
Site 2
S19
S
F
D
C
L
N
D
S
N
V
P
V
Y
S
S
Site 3
Y24
N
D
S
N
V
P
V
Y
S
S
G
D
T
V
S
Site 4
S25
D
S
N
V
P
V
Y
S
S
G
D
T
V
S
G
Site 5
T29
P
V
Y
S
S
G
D
T
V
S
G
R
V
N
L
Site 6
S31
Y
S
S
G
D
T
V
S
G
R
V
N
L
E
V
Site 7
S46
T
G
E
I
R
V
K
S
L
K
I
H
A
R
G
Site 8
T60
G
H
A
K
V
R
W
T
E
S
R
N
A
G
S
Site 9
S62
A
K
V
R
W
T
E
S
R
N
A
G
S
N
T
Site 10
Y71
N
A
G
S
N
T
A
Y
T
Q
N
Y
T
E
E
Site 11
Y81
N
Y
T
E
E
V
E
Y
F
N
H
K
D
I
L
Site 12
S98
H
E
R
D
D
D
N
S
E
E
G
F
H
T
I
Site 13
T104
N
S
E
E
G
F
H
T
I
H
S
G
R
H
E
Site 14
Y112
I
H
S
G
R
H
E
Y
A
F
S
F
E
L
P
Site 15
S115
G
R
H
E
Y
A
F
S
F
E
L
P
Q
T
P
Site 16
T121
F
S
F
E
L
P
Q
T
P
L
A
T
S
F
E
Site 17
S126
P
Q
T
P
L
A
T
S
F
E
G
R
H
G
S
Site 18
S133
S
F
E
G
R
H
G
S
V
R
Y
W
V
K
A
Site 19
T166
F
E
H
I
D
I
N
T
P
S
L
L
S
P
Q
Site 20
S168
H
I
D
I
N
T
P
S
L
L
S
P
Q
A
G
Site 21
S171
I
N
T
P
S
L
L
S
P
Q
A
G
T
K
E
Site 22
S192
F
C
T
S
G
P
I
S
L
S
A
K
I
E
R
Site 23
S194
T
S
G
P
I
S
L
S
A
K
I
E
R
K
G
Site 24
Y202
A
K
I
E
R
K
G
Y
T
P
G
E
S
I
Q
Site 25
T203
K
I
E
R
K
G
Y
T
P
G
E
S
I
Q
I
Site 26
S207
K
G
Y
T
P
G
E
S
I
Q
I
F
A
E
I
Site 27
S218
F
A
E
I
E
N
C
S
S
R
M
V
V
P
K
Site 28
S219
A
E
I
E
N
C
S
S
R
M
V
V
P
K
A
Site 29
S254
V
A
N
L
R
G
E
S
L
S
S
G
K
T
E
Site 30
S256
N
L
R
G
E
S
L
S
S
G
K
T
E
T
W
Site 31
S257
L
R
G
E
S
L
S
S
G
K
T
E
T
W
N
Site 32
T260
E
S
L
S
S
G
K
T
E
T
W
N
G
K
L
Site 33
T262
L
S
S
G
K
T
E
T
W
N
G
K
L
L
K
Site 34
S319
I
P
L
H
P
F
G
S
R
T
S
S
V
S
S
Site 35
T321
L
H
P
F
G
S
R
T
S
S
V
S
S
Q
C
Site 36
S322
H
P
F
G
S
R
T
S
S
V
S
S
Q
C
S
Site 37
S323
P
F
G
S
R
T
S
S
V
S
S
Q
C
S
M
Site 38
S325
G
S
R
T
S
S
V
S
S
Q
C
S
M
N
M
Site 39
S326
S
R
T
S
S
V
S
S
Q
C
S
M
N
M
N
Site 40
S329
S
S
V
S
S
Q
C
S
M
N
M
N
W
L
S
Site 41
S336
S
M
N
M
N
W
L
S
L
S
L
P
E
R
P
Site 42
S338
N
M
N
W
L
S
L
S
L
P
E
R
P
E
A
Site 43
S348
E
R
P
E
A
P
P
S
Y
A
E
V
V
T
E
Site 44
Y349
R
P
E
A
P
P
S
Y
A
E
V
V
T
E
E
Site 45
S366
R
N
N
L
A
P
V
S
A
C
D
D
F
E
R
Site 46
Y382
L
Q
G
P
L
F
A
Y
I
Q
E
F
R
F
L
Site 47
Y394
R
F
L
P
P
P
L
Y
S
E
I
D
P
N
P
Site 48
S395
F
L
P
P
P
L
Y
S
E
I
D
P
N
P
D
Site 49
S404
I
D
P
N
P
D
Q
S
A
D
D
R
P
S
C
Site 50
S410
Q
S
A
D
D
R
P
S
C
P
S
R
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation