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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLCO4A1
Full Name:
Solute carrier organic anion transporter family member 4A1
Alias:
Colon organic anion transporter; OATP1; OATP4A1; OATPE; OATP-E; OATPRP1; OATP-RP1; Organic anion transporter polypeptide-related protein 1; Organic anion transporting polypeptide E; Organic anion-transporting polypeptide E; POAT; SLC21A12; SO41; SO4A1; Sodium-independent organic anion transporter E; Solute carrier family 21 member 12; Solute carrier organic anion transporter family, member 4A1
Type:
Transporter
Mass (Da):
77193
Number AA:
722
UniProt ID:
Q96BD0
International Prot ID:
IPI00100858
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0016021
GO:0031224
Uniprot
OncoNet
Molecular Function:
GO:0005215
GO:0005215
GO:0005215
PhosphoSite+
KinaseNET
Biological Process:
GO:0006811
GO:0006811
GO:0051234
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
Q
L
G
D
K
P
L
T
F
P
S
P
N
S
A
Site 2
S15
D
K
P
L
T
F
P
S
P
N
S
A
M
E
N
Site 3
S18
L
T
F
P
S
P
N
S
A
M
E
N
G
L
D
Site 4
T27
M
E
N
G
L
D
H
T
P
P
S
R
R
A
S
Site 5
S30
G
L
D
H
T
P
P
S
R
R
A
S
P
G
T
Site 6
S34
T
P
P
S
R
R
A
S
P
G
T
P
L
S
P
Site 7
T37
S
R
R
A
S
P
G
T
P
L
S
P
G
S
L
Site 8
S40
A
S
P
G
T
P
L
S
P
G
S
L
R
S
A
Site 9
S43
G
T
P
L
S
P
G
S
L
R
S
A
A
H
S
Site 10
S46
L
S
P
G
S
L
R
S
A
A
H
S
P
L
D
Site 11
S50
S
L
R
S
A
A
H
S
P
L
D
T
S
K
Q
Site 12
T54
A
A
H
S
P
L
D
T
S
K
Q
P
L
C
Q
Site 13
S55
A
H
S
P
L
D
T
S
K
Q
P
L
C
Q
L
Site 14
T72
E
K
H
G
A
R
G
T
H
E
V
R
Y
V
S
Site 15
Y77
R
G
T
H
E
V
R
Y
V
S
A
G
Q
S
V
Site 16
S79
T
H
E
V
R
Y
V
S
A
G
Q
S
V
A
C
Site 17
S130
F
I
N
T
V
I
T
S
L
E
R
R
Y
D
L
Site 18
Y135
I
T
S
L
E
R
R
Y
D
L
H
S
Y
Q
S
Site 19
S139
E
R
R
Y
D
L
H
S
Y
Q
S
G
L
I
A
Site 20
Y140
R
R
Y
D
L
H
S
Y
Q
S
G
L
I
A
S
Site 21
S142
Y
D
L
H
S
Y
Q
S
G
L
I
A
S
S
Y
Site 22
Y197
P
H
F
T
A
G
R
Y
E
V
E
L
D
A
G
Site 23
S219
P
G
A
V
C
A
D
S
T
S
G
L
S
R
Y
Site 24
T220
G
A
V
C
A
D
S
T
S
G
L
S
R
Y
Q
Site 25
S221
A
V
C
A
D
S
T
S
G
L
S
R
Y
Q
L
Site 26
S258
Y
L
D
E
N
V
K
S
S
C
S
P
V
Y
I
Site 27
Y290
G
G
A
L
L
N
I
Y
T
E
M
G
R
R
T
Site 28
T297
Y
T
E
M
G
R
R
T
E
L
T
T
E
S
P
Site 29
T300
M
G
R
R
T
E
L
T
T
E
S
P
L
W
V
Site 30
T301
G
R
R
T
E
L
T
T
E
S
P
L
W
V
G
Site 31
S303
R
T
E
L
T
T
E
S
P
L
W
V
G
A
W
Site 32
S338
Y
P
R
Q
L
P
G
S
Q
R
Y
A
V
M
R
Site 33
S355
E
M
H
Q
L
K
D
S
S
R
G
E
A
S
N
Site 34
T368
S
N
P
D
F
G
K
T
I
R
D
L
P
L
S
Site 35
S406
I
T
G
M
S
T
F
S
P
K
F
L
E
S
Q
Site 36
S412
F
S
P
K
F
L
E
S
Q
F
S
L
S
A
S
Site 37
S415
K
F
L
E
S
Q
F
S
L
S
A
S
E
A
A
Site 38
Y515
C
S
C
Q
P
E
H
Y
S
P
V
C
G
S
D
Site 39
S516
S
C
Q
P
E
H
Y
S
P
V
C
G
S
D
G
Site 40
Y548
N
V
D
G
Q
K
V
Y
R
D
C
S
C
I
P
Site 41
S552
Q
K
V
Y
R
D
C
S
C
I
P
Q
N
L
S
Site 42
T566
S
S
G
F
G
H
A
T
A
G
K
C
T
S
T
Site 43
S572
A
T
A
G
K
C
T
S
T
C
Q
R
K
P
L
Site 44
T573
T
A
G
K
C
T
S
T
C
Q
R
K
P
L
L
Site 45
Y658
Q
Q
G
S
C
L
V
Y
Q
N
S
A
M
S
R
Site 46
S693
C
F
L
Y
K
P
L
S
E
S
S
D
G
L
E
Site 47
S695
L
Y
K
P
L
S
E
S
S
D
G
L
E
T
C
Site 48
T701
E
S
S
D
G
L
E
T
C
L
P
S
Q
S
S
Site 49
S705
G
L
E
T
C
L
P
S
Q
S
S
A
P
D
S
Site 50
S707
E
T
C
L
P
S
Q
S
S
A
P
D
S
A
T
Site 51
S708
T
C
L
P
S
Q
S
S
A
P
D
S
A
T
D
Site 52
S712
S
Q
S
S
A
P
D
S
A
T
D
S
Q
L
Q
Site 53
T714
S
S
A
P
D
S
A
T
D
S
Q
L
Q
S
S
Site 54
S716
A
P
D
S
A
T
D
S
Q
L
Q
S
S
V
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation