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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PHF21A
Full Name:
PHD finger protein 21A
Alias:
BHC80; BM-006; kiaa1696; PF21A
Type:
Adapter/scaffold protein
Mass (Da):
74854
Number AA:
680
UniProt ID:
Q96BD5
International Prot ID:
IPI00054460
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000118
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0016568
GO:0000122
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S48
Q
A
K
I
T
A
L
S
E
K
Q
K
R
V
V
Site 2
S80
Q
I
Q
P
L
P
Q
S
E
N
K
L
Q
T
A
Site 3
S109
H
H
H
H
A
Q
Q
S
A
A
A
S
P
N
L
Site 4
S113
A
Q
Q
S
A
A
A
S
P
N
L
T
A
S
Q
Site 5
T117
A
A
A
S
P
N
L
T
A
S
Q
K
T
V
T
Site 6
S119
A
S
P
N
L
T
A
S
Q
K
T
V
T
T
A
Site 7
S148
A
T
A
T
M
P
A
S
V
V
G
Q
R
P
T
Site 8
T176
L
S
T
D
V
Q
N
T
P
V
N
L
Q
T
S
Site 9
S183
T
P
V
N
L
Q
T
S
S
K
V
T
G
P
G
Site 10
S184
P
V
N
L
Q
T
S
S
K
V
T
G
P
G
A
Site 11
T225
F
I
P
P
P
R
L
T
P
R
P
N
F
L
P
Site 12
T273
L
T
K
F
T
P
T
T
L
P
T
S
Q
N
S
Site 13
T276
F
T
P
T
T
L
P
T
S
Q
N
S
I
H
P
Site 14
S277
T
P
T
T
L
P
T
S
Q
N
S
I
H
P
V
Site 15
T320
T
R
L
A
G
P
Q
T
V
Q
L
S
K
P
S
Site 16
S324
G
P
Q
T
V
Q
L
S
K
P
S
L
E
K
Q
Site 17
S335
L
E
K
Q
T
V
K
S
H
T
E
T
D
E
K
Site 18
T339
T
V
K
S
H
T
E
T
D
E
K
Q
T
E
S
Site 19
T344
T
E
T
D
E
K
Q
T
E
S
R
T
I
T
P
Site 20
S346
T
D
E
K
Q
T
E
S
R
T
I
T
P
P
A
Site 21
T350
Q
T
E
S
R
T
I
T
P
P
A
A
P
K
P
Site 22
S385
D
H
L
E
E
I
Q
S
K
R
Q
E
R
K
R
Site 23
T394
R
Q
E
R
K
R
R
T
T
A
N
P
V
Y
S
Site 24
T395
Q
E
R
K
R
R
T
T
A
N
P
V
Y
S
G
Site 25
Y400
R
T
T
A
N
P
V
Y
S
G
A
V
F
E
P
Site 26
S412
F
E
P
E
R
K
K
S
A
V
T
Y
L
N
S
Site 27
Y416
R
K
K
S
A
V
T
Y
L
N
S
T
M
H
P
Site 28
S419
S
A
V
T
Y
L
N
S
T
M
H
P
G
T
R
Site 29
T420
A
V
T
Y
L
N
S
T
M
H
P
G
T
R
K
Site 30
Y434
K
R
G
R
P
P
K
Y
N
A
V
L
G
F
G
Site 31
T444
V
L
G
F
G
A
L
T
P
T
S
P
Q
S
S
Site 32
T446
G
F
G
A
L
T
P
T
S
P
Q
S
S
H
P
Site 33
S447
F
G
A
L
T
P
T
S
P
Q
S
S
H
P
D
Site 34
S450
L
T
P
T
S
P
Q
S
S
H
P
D
S
P
E
Site 35
S451
T
P
T
S
P
Q
S
S
H
P
D
S
P
E
N
Site 36
S455
P
Q
S
S
H
P
D
S
P
E
N
E
K
T
E
Site 37
T461
D
S
P
E
N
E
K
T
E
T
T
F
T
F
P
Site 38
T463
P
E
N
E
K
T
E
T
T
F
T
F
P
A
P
Site 39
T466
E
K
T
E
T
T
F
T
F
P
A
P
V
Q
P
Site 40
S475
P
A
P
V
Q
P
V
S
L
P
S
P
T
S
T
Site 41
S478
V
Q
P
V
S
L
P
S
P
T
S
T
D
G
D
Site 42
S481
V
S
L
P
S
P
T
S
T
D
G
D
I
H
E
Site 43
T482
S
L
P
S
P
T
S
T
D
G
D
I
H
E
D
Site 44
Y510
C
D
T
C
S
R
V
Y
H
L
D
C
L
D
P
Site 45
Y558
I
V
H
S
Y
I
A
Y
K
A
A
K
E
E
E
Site 46
S574
Q
K
L
L
K
W
S
S
D
L
K
Q
E
R
E
Site 47
S591
E
Q
K
V
K
Q
L
S
N
S
I
S
K
C
M
Site 48
S593
K
V
K
Q
L
S
N
S
I
S
K
C
M
E
M
Site 49
S595
K
Q
L
S
N
S
I
S
K
C
M
E
M
K
N
Site 50
T603
K
C
M
E
M
K
N
T
I
L
A
R
Q
K
E
Site 51
S614
R
Q
K
E
M
H
S
S
L
E
K
V
K
Q
L
Site 52
S631
L
I
H
G
I
D
L
S
K
P
V
D
S
E
A
Site 53
T639
K
P
V
D
S
E
A
T
V
G
A
I
S
N
G
Site 54
T650
I
S
N
G
P
D
C
T
P
P
A
N
A
A
T
Site 55
T657
T
P
P
A
N
A
A
T
S
T
P
A
P
S
P
Site 56
S658
P
P
A
N
A
A
T
S
T
P
A
P
S
P
S
Site 57
T659
P
A
N
A
A
T
S
T
P
A
P
S
P
S
S
Site 58
S663
A
T
S
T
P
A
P
S
P
S
S
Q
S
C
T
Site 59
S665
S
T
P
A
P
S
P
S
S
Q
S
C
T
A
N
Site 60
S666
T
P
A
P
S
P
S
S
Q
S
C
T
A
N
C
Site 61
S668
A
P
S
P
S
S
Q
S
C
T
A
N
C
N
Q
Site 62
T670
S
P
S
S
Q
S
C
T
A
N
C
N
Q
G
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation