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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PINX1
Full Name:
PIN2/TERF1-interacting telomerase inhibitor 1
Alias:
Liver-related putative tumor suppressor; LPTL; LPTS; PIN2-interacting 1; Protein 67-11-3; TRF1-interacting 1; TRF1-interacting protein 1
Type:
Inhibitor protein
Mass (Da):
37035
Number AA:
328
UniProt ID:
Q96BK5
International Prot ID:
IPI00297357
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000781
GO:0000777
GO:0000228
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0010521
GO:0070034
PhosphoSite+
KinaseNET
Biological Process:
GO:0007080
GO:0008285
GO:0051972
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S23
D
P
Q
N
T
A
W
S
N
D
D
S
K
F
G
Site 2
S27
T
A
W
S
N
D
D
S
K
F
G
Q
R
M
L
Site 3
T53
G
A
Q
E
Q
G
A
T
D
H
I
K
V
Q
V
Site 4
S102
H
G
Q
E
T
T
D
S
S
D
K
K
E
K
K
Site 5
S103
G
Q
E
T
T
D
S
S
D
K
K
E
K
K
S
Site 6
S110
S
D
K
K
E
K
K
S
F
S
L
E
E
K
S
Site 7
S112
K
K
E
K
K
S
F
S
L
E
E
K
S
K
I
Site 8
S117
S
F
S
L
E
E
K
S
K
I
S
K
N
R
V
Site 9
S120
L
E
E
K
S
K
I
S
K
N
R
V
H
Y
M
Site 10
Y126
I
S
K
N
R
V
H
Y
M
K
F
T
K
G
K
Site 11
S136
F
T
K
G
K
D
L
S
S
R
S
K
T
D
L
Site 12
S137
T
K
G
K
D
L
S
S
R
S
K
T
D
L
D
Site 13
S139
G
K
D
L
S
S
R
S
K
T
D
L
D
C
I
Site 14
T141
D
L
S
S
R
S
K
T
D
L
D
C
I
F
G
Site 15
S152
C
I
F
G
K
R
Q
S
K
K
T
P
E
G
D
Site 16
T155
G
K
R
Q
S
K
K
T
P
E
G
D
A
S
P
Site 17
S161
K
T
P
E
G
D
A
S
P
S
T
P
E
E
N
Site 18
S163
P
E
G
D
A
S
P
S
T
P
E
E
N
E
T
Site 19
T164
E
G
D
A
S
P
S
T
P
E
E
N
E
T
T
Site 20
T170
S
T
P
E
E
N
E
T
T
T
T
S
A
F
T
Site 21
T171
T
P
E
E
N
E
T
T
T
T
S
A
F
T
I
Site 22
T173
E
E
N
E
T
T
T
T
S
A
F
T
I
Q
E
Site 23
S174
E
N
E
T
T
T
T
S
A
F
T
I
Q
E
Y
Site 24
Y181
S
A
F
T
I
Q
E
Y
F
A
K
R
M
A
A
Site 25
S200
P
Q
V
P
V
P
G
S
D
I
S
E
T
Q
V
Site 26
T205
P
G
S
D
I
S
E
T
Q
V
E
R
K
R
G
Site 27
T220
K
K
R
N
K
E
A
T
G
K
D
V
E
S
Y
Site 28
S226
A
T
G
K
D
V
E
S
Y
L
Q
P
K
A
K
Site 29
Y227
T
G
K
D
V
E
S
Y
L
Q
P
K
A
K
R
Site 30
T236
Q
P
K
A
K
R
H
T
E
G
K
P
E
R
A
Site 31
S254
E
R
V
A
K
K
K
S
A
P
A
E
E
Q
L
Site 32
S269
R
G
P
C
W
D
Q
S
S
K
A
S
A
Q
D
Site 33
S270
G
P
C
W
D
Q
S
S
K
A
S
A
Q
D
A
Site 34
S273
W
D
Q
S
S
K
A
S
A
Q
D
A
G
D
H
Site 35
T290
P
P
E
G
R
D
F
T
L
K
P
K
K
R
R
Site 36
T317
E
D
A
T
L
E
E
T
L
V
K
K
K
K
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation