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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CENPT
Full Name:
Centromere protein T
Alias:
C16orf56; CENP-T; Cenp-t; Centromere protein T; Flj13111; Interphase centromere complex protein 22
Type:
DNA replication
Mass (Da):
60423
Number AA:
561
UniProt ID:
Q96BT3
International Prot ID:
IPI00465368
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000777
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0043565
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
A
D
H
N
P
D
S
D
S
T
P
R
T
L
Site 2
S10
D
H
N
P
D
S
D
S
T
P
R
T
L
L
R
Site 3
T11
H
N
P
D
S
D
S
T
P
R
T
L
L
R
R
Site 4
T14
D
S
D
S
T
P
R
T
L
L
R
R
V
L
D
Site 5
T22
L
L
R
R
V
L
D
T
A
D
P
R
T
P
R
Site 6
T27
L
D
T
A
D
P
R
T
P
R
R
P
R
S
A
Site 7
S33
R
T
P
R
R
P
R
S
A
R
A
G
A
R
R
Site 8
T45
A
R
R
A
L
L
E
T
A
S
P
R
K
L
S
Site 9
S47
R
A
L
L
E
T
A
S
P
R
K
L
S
G
Q
Site 10
S52
T
A
S
P
R
K
L
S
G
Q
T
R
T
I
A
Site 11
T57
K
L
S
G
Q
T
R
T
I
A
R
G
R
S
H
Site 12
S63
R
T
I
A
R
G
R
S
H
G
A
R
S
V
G
Site 13
S68
G
R
S
H
G
A
R
S
V
G
R
S
A
H
I
Site 14
S72
G
A
R
S
V
G
R
S
A
H
I
Q
A
S
G
Site 15
T85
S
G
H
L
E
E
Q
T
P
R
T
L
L
K
N
Site 16
S121
A
P
Q
A
V
Q
P
S
R
Q
E
S
S
C
G
Site 17
S125
V
Q
P
S
R
Q
E
S
S
C
G
S
L
E
L
Site 18
S126
Q
P
S
R
Q
E
S
S
C
G
S
L
E
L
Q
Site 19
S129
R
Q
E
S
S
C
G
S
L
E
L
Q
L
P
E
Site 20
S160
R
K
Q
R
L
R
L
S
V
F
Q
Q
G
V
D
Site 21
S171
Q
G
V
D
Q
G
L
S
L
S
Q
E
P
Q
G
Site 22
S173
V
D
Q
G
L
S
L
S
Q
E
P
Q
G
N
A
Site 23
S183
P
Q
G
N
A
D
A
S
S
L
T
R
S
L
N
Site 24
S184
Q
G
N
A
D
A
S
S
L
T
R
S
L
N
L
Site 25
S188
D
A
S
S
L
T
R
S
L
N
L
T
F
A
T
Site 26
T192
L
T
R
S
L
N
L
T
F
A
T
P
L
Q
P
Site 27
T195
S
L
N
L
T
F
A
T
P
L
Q
P
Q
S
V
Site 28
S201
A
T
P
L
Q
P
Q
S
V
Q
R
P
G
L
A
Site 29
T229
F
L
R
D
L
R
D
T
S
L
A
P
P
N
I
Site 30
S230
L
R
D
L
R
D
T
S
L
A
P
P
N
I
V
Site 31
T241
P
N
I
V
L
E
D
T
Q
P
F
S
Q
P
M
Site 32
S245
L
E
D
T
Q
P
F
S
Q
P
M
V
G
S
P
Site 33
S251
F
S
Q
P
M
V
G
S
P
N
V
Y
H
S
L
Site 34
Y255
M
V
G
S
P
N
V
Y
H
S
L
P
C
T
P
Site 35
S257
G
S
P
N
V
Y
H
S
L
P
C
T
P
H
T
Site 36
T261
V
Y
H
S
L
P
C
T
P
H
T
G
A
E
D
Site 37
T277
E
Q
A
A
G
R
K
T
Q
S
S
G
P
G
L
Site 38
S279
A
A
G
R
K
T
Q
S
S
G
P
G
L
Q
K
Site 39
S280
A
G
R
K
T
Q
S
S
G
P
G
L
Q
K
N
Site 40
S288
G
P
G
L
Q
K
N
S
P
G
K
P
A
Q
F
Site 41
S318
L
S
T
S
S
G
V
S
G
E
D
E
V
E
P
Site 42
S343
K
M
E
E
E
G
V
S
V
S
E
M
E
A
T
Site 43
T350
S
V
S
E
M
E
A
T
G
A
Q
G
P
S
R
Site 44
S373
E
V
T
E
A
E
G
S
Q
G
T
A
E
A
D
Site 45
S385
E
A
D
G
P
G
A
S
S
G
D
E
D
A
S
Site 46
S386
A
D
G
P
G
A
S
S
G
D
E
D
A
S
G
Site 47
S392
S
S
G
D
E
D
A
S
G
R
A
A
S
P
E
Site 48
S397
D
A
S
G
R
A
A
S
P
E
S
A
S
S
T
Site 49
S400
G
R
A
A
S
P
E
S
A
S
S
T
P
E
S
Site 50
S402
A
A
S
P
E
S
A
S
S
T
P
E
S
L
Q
Site 51
S403
A
S
P
E
S
A
S
S
T
P
E
S
L
Q
A
Site 52
T404
S
P
E
S
A
S
S
T
P
E
S
L
Q
A
R
Site 53
S407
S
A
S
S
T
P
E
S
L
Q
A
R
R
H
H
Site 54
T446
R
H
P
P
R
P
R
T
T
G
P
R
P
R
Q
Site 55
T447
H
P
P
R
P
R
T
T
G
P
R
P
R
Q
D
Site 56
S461
D
P
H
K
A
G
L
S
H
Y
V
K
L
F
S
Site 57
Y463
H
K
A
G
L
S
H
Y
V
K
L
F
S
F
Y
Site 58
S468
S
H
Y
V
K
L
F
S
F
Y
A
K
M
P
M
Site 59
Y470
Y
V
K
L
F
S
F
Y
A
K
M
P
M
E
R
Site 60
Y490
V
E
K
C
L
D
K
Y
F
Q
H
L
C
D
D
Site 61
T509
A
A
H
A
G
R
K
T
V
K
P
E
D
L
E
Site 62
T526
M
R
R
Q
G
L
V
T
D
Q
V
S
L
H
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation