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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SYTL4
Full Name:
Synaptotagmin-like protein 4
Alias:
Exophilin-2; Granuphilin; Granuphilin-a; Synaptotagmin-like 4; Synaptotagmin-like protein 4: Exophilin-2: Granuphilin: Synaptotagmin-like protein 4: Exophilin-2: Granuphilin
Type:
Vesicle protein
Mass (Da):
76010
Number AA:
671
UniProt ID:
Q96C24
International Prot ID:
IPI00060201
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0019898
GO:0005886
GO:0008021
Uniprot
OncoNet
Molecular Function:
GO:0017137
GO:0042043
GO:0005543
PhosphoSite+
KinaseNET
Biological Process:
GO:0006887
GO:0006886
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
S
E
L
L
D
L
S
F
L
S
E
E
E
K
Site 2
S20
E
E
K
D
L
I
L
S
V
L
Q
R
D
E
E
Site 3
S55
R
K
G
A
K
R
G
S
Q
H
Y
S
D
R
T
Site 4
Y58
A
K
R
G
S
Q
H
Y
S
D
R
T
C
A
R
Site 5
S59
K
R
G
S
Q
H
Y
S
D
R
T
C
A
R
C
Site 6
T62
S
Q
H
Y
S
D
R
T
C
A
R
C
Q
E
S
Site 7
S69
T
C
A
R
C
Q
E
S
L
G
R
L
S
P
K
Site 8
S74
Q
E
S
L
G
R
L
S
P
K
T
N
T
C
R
Site 9
T77
L
G
R
L
S
P
K
T
N
T
C
R
G
C
N
Site 10
T79
R
L
S
P
K
T
N
T
C
R
G
C
N
H
L
Site 11
Y120
K
A
T
G
D
W
F
Y
D
Q
K
V
N
R
F
Site 12
Y129
Q
K
V
N
R
F
A
Y
R
T
G
S
E
I
I
Site 13
T131
V
N
R
F
A
Y
R
T
G
S
E
I
I
R
M
Site 14
S133
R
F
A
Y
R
T
G
S
E
I
I
R
M
S
L
Site 15
S139
G
S
E
I
I
R
M
S
L
R
H
K
P
A
V
Site 16
S147
L
R
H
K
P
A
V
S
K
R
E
T
V
G
Q
Site 17
T151
P
A
V
S
K
R
E
T
V
G
Q
S
L
L
H
Site 18
S180
Q
E
R
Q
K
E
P
S
V
L
F
E
V
P
K
Site 19
S190
F
E
V
P
K
L
K
S
G
K
S
A
L
E
A
Site 20
S193
P
K
L
K
S
G
K
S
A
L
E
A
E
S
E
Site 21
S199
K
S
A
L
E
A
E
S
E
S
L
D
S
F
T
Site 22
S201
A
L
E
A
E
S
E
S
L
D
S
F
T
A
D
Site 23
S204
A
E
S
E
S
L
D
S
F
T
A
D
S
D
S
Site 24
T206
S
E
S
L
D
S
F
T
A
D
S
D
S
T
S
Site 25
S209
L
D
S
F
T
A
D
S
D
S
T
S
R
R
D
Site 26
S211
S
F
T
A
D
S
D
S
T
S
R
R
D
S
L
Site 27
T212
F
T
A
D
S
D
S
T
S
R
R
D
S
L
D
Site 28
S213
T
A
D
S
D
S
T
S
R
R
D
S
L
D
K
Site 29
S217
D
S
T
S
R
R
D
S
L
D
K
S
G
L
F
Site 30
S221
R
R
D
S
L
D
K
S
G
L
F
P
E
W
K
Site 31
S231
F
P
E
W
K
K
M
S
A
P
K
S
Q
V
E
Site 32
S235
K
K
M
S
A
P
K
S
Q
V
E
K
E
T
Q
Site 33
S269
T
R
K
I
L
R
P
S
E
Y
T
K
S
V
I
Site 34
S274
R
P
S
E
Y
T
K
S
V
I
D
L
R
P
E
Site 35
S287
P
E
D
V
V
H
E
S
G
S
L
G
D
R
S
Site 36
S289
D
V
V
H
E
S
G
S
L
G
D
R
S
K
S
Site 37
S294
S
G
S
L
G
D
R
S
K
S
V
P
G
L
N
Site 38
S296
S
L
G
D
R
S
K
S
V
P
G
L
N
V
D
Site 39
S327
H
R
Q
K
L
A
R
S
S
M
Q
S
G
S
S
Site 40
S328
R
Q
K
L
A
R
S
S
M
Q
S
G
S
S
M
Site 41
S331
L
A
R
S
S
M
Q
S
G
S
S
M
S
T
I
Site 42
S333
R
S
S
M
Q
S
G
S
S
M
S
T
I
G
S
Site 43
S334
S
S
M
Q
S
G
S
S
M
S
T
I
G
S
M
Site 44
S336
M
Q
S
G
S
S
M
S
T
I
G
S
M
M
S
Site 45
T337
Q
S
G
S
S
M
S
T
I
G
S
M
M
S
I
Site 46
S340
S
S
M
S
T
I
G
S
M
M
S
I
Y
S
E
Site 47
S343
S
T
I
G
S
M
M
S
I
Y
S
E
A
G
D
Site 48
S346
G
S
M
M
S
I
Y
S
E
A
G
D
F
G
N
Site 49
S363
V
T
G
R
I
A
F
S
L
K
Y
E
Q
Q
T
Site 50
Y366
R
I
A
F
S
L
K
Y
E
Q
Q
T
Q
S
L
Site 51
S372
K
Y
E
Q
Q
T
Q
S
L
V
V
H
V
K
E
Site 52
Y396
A
K
K
R
S
N
P
Y
V
K
T
Y
L
L
P
Site 53
Y400
S
N
P
Y
V
K
T
Y
L
L
P
D
K
S
R
Site 54
S406
T
Y
L
L
P
D
K
S
R
Q
G
K
R
K
T
Site 55
T413
S
R
Q
G
K
R
K
T
S
I
K
R
D
T
V
Site 56
S414
R
Q
G
K
R
K
T
S
I
K
R
D
T
V
N
Site 57
T419
K
T
S
I
K
R
D
T
V
N
P
L
Y
D
E
Site 58
Y424
R
D
T
V
N
P
L
Y
D
E
T
L
R
Y
E
Site 59
T427
V
N
P
L
Y
D
E
T
L
R
Y
E
I
P
E
Site 60
Y430
L
Y
D
E
T
L
R
Y
E
I
P
E
S
L
L
Site 61
S435
L
R
Y
E
I
P
E
S
L
L
A
Q
R
T
L
Site 62
T441
E
S
L
L
A
Q
R
T
L
Q
F
S
V
W
H
Site 63
T456
H
G
R
F
G
R
N
T
F
L
G
E
A
E
I
Site 64
S485
L
P
L
H
G
K
I
S
A
E
S
P
T
G
L
Site 65
S488
H
G
K
I
S
A
E
S
P
T
G
L
P
S
H
Site 66
T490
K
I
S
A
E
S
P
T
G
L
P
S
H
K
G
Site 67
S494
E
S
P
T
G
L
P
S
H
K
G
E
L
V
V
Site 68
S509
S
L
K
Y
I
P
A
S
K
T
P
V
G
G
D
Site 69
T511
K
Y
I
P
A
S
K
T
P
V
G
G
D
R
K
Site 70
S520
V
G
G
D
R
K
K
S
K
G
G
E
G
G
E
Site 71
T546
T
A
A
K
A
G
G
T
S
D
S
F
V
K
G
Site 72
S547
A
A
K
A
G
G
T
S
D
S
F
V
K
G
Y
Site 73
S549
K
A
G
G
T
S
D
S
F
V
K
G
Y
L
L
Site 74
Y554
S
D
S
F
V
K
G
Y
L
L
P
M
R
N
K
Site 75
S563
L
P
M
R
N
K
A
S
K
R
K
T
P
V
M
Site 76
T567
N
K
A
S
K
R
K
T
P
V
M
K
K
T
L
Site 77
T573
K
T
P
V
M
K
K
T
L
N
P
H
Y
N
H
Site 78
Y578
K
K
T
L
N
P
H
Y
N
H
T
F
V
Y
N
Site 79
Y584
H
Y
N
H
T
F
V
Y
N
G
V
R
L
E
D
Site 80
S609
W
D
R
E
P
L
A
S
N
D
F
L
G
G
V
Site 81
S635
E
V
V
D
W
M
D
S
T
G
E
E
V
S
L
Site 82
T636
V
V
D
W
M
D
S
T
G
E
E
V
S
L
W
Site 83
S641
D
S
T
G
E
E
V
S
L
W
Q
K
M
R
Q
Site 84
Y649
L
W
Q
K
M
R
Q
Y
P
G
S
W
A
E
G
Site 85
S652
K
M
R
Q
Y
P
G
S
W
A
E
G
T
L
Q
Site 86
T657
P
G
S
W
A
E
G
T
L
Q
L
R
S
S
M
Site 87
S662
E
G
T
L
Q
L
R
S
S
M
A
K
Q
K
L
Site 88
S663
G
T
L
Q
L
R
S
S
M
A
K
Q
K
L
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation