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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NSUN4
Full Name:
Putative methyltransferase NSUN4
Alias:
EC 2.1.1.-; Methyltransferase NSUN4; NOL1/NOP2/Sun domain family member 4; NOL1/NOP2/Sun domain family, member 4
Type:
Mass (Da):
43089
Number AA:
384
UniProt ID:
Q96CB9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0008168
GO:0008168
GO:0016740
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T20
L
K
R
V
D
L
A
T
V
P
R
R
H
R
Y
Site 2
Y27
T
V
P
R
R
H
R
Y
K
K
K
W
A
A
T
Site 3
T34
Y
K
K
K
W
A
A
T
E
P
K
F
P
A
V
Site 4
Y52
L
Q
N
F
D
M
T
Y
S
V
Q
F
G
D
L
Site 5
S66
L
W
P
S
I
R
V
S
L
L
S
E
Q
K
Y
Site 6
S69
S
I
R
V
S
L
L
S
E
Q
K
Y
G
A
L
Site 7
Y73
S
L
L
S
E
Q
K
Y
G
A
L
V
N
N
F
Site 8
S94
S
A
K
L
E
Q
L
S
A
K
D
F
V
N
E
Site 9
S104
D
F
V
N
E
A
I
S
H
W
E
L
Q
S
E
Site 10
S115
L
Q
S
E
G
G
Q
S
A
A
P
S
P
A
S
Site 11
S119
G
G
Q
S
A
A
P
S
P
A
S
W
A
C
S
Site 12
S122
S
A
A
P
S
P
A
S
W
A
C
S
P
N
L
Site 13
S126
S
P
A
S
W
A
C
S
P
N
L
R
C
F
T
Site 14
T133
S
P
N
L
R
C
F
T
F
D
R
G
D
I
S
Site 15
S140
T
F
D
R
G
D
I
S
R
F
P
P
A
R
P
Site 16
S149
F
P
P
A
R
P
G
S
L
G
V
M
E
Y
Y
Site 17
S206
N
L
A
A
N
D
L
S
P
S
R
I
A
R
L
Site 18
S219
R
L
Q
K
I
L
H
S
Y
V
P
E
E
I
R
Site 19
Y220
L
Q
K
I
L
H
S
Y
V
P
E
E
I
R
D
Site 20
S235
G
N
Q
V
R
V
T
S
W
D
G
R
K
W
G
Site 21
T248
W
G
E
L
E
G
D
T
Y
D
R
V
L
V
D
Site 22
Y249
G
E
L
E
G
D
T
Y
D
R
V
L
V
D
V
Site 23
T259
V
L
V
D
V
P
C
T
T
D
R
H
S
L
H
Site 24
T260
L
V
D
V
P
C
T
T
D
R
H
S
L
H
E
Site 25
S264
P
C
T
T
D
R
H
S
L
H
E
E
E
N
N
Site 26
Y307
K
P
G
G
H
V
V
Y
S
T
C
S
L
S
H
Site 27
S311
H
V
V
Y
S
T
C
S
L
S
H
L
Q
N
E
Site 28
S313
V
Y
S
T
C
S
L
S
H
L
Q
N
E
Y
V
Site 29
Y319
L
S
H
L
Q
N
E
Y
V
V
Q
G
A
I
E
Site 30
S333
E
L
L
A
N
Q
Y
S
I
Q
V
Q
V
E
D
Site 31
T342
Q
V
Q
V
E
D
L
T
H
F
R
R
V
F
M
Site 32
Y376
M
A
N
F
G
P
M
Y
F
C
K
M
R
R
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation