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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EAF2
Full Name:
ELL-associated factor 2
Alias:
BM040; BM-040; ELL associated factor 2; Testosterone-regulated apoptosis inducer and tumor suppressor protein; TRAITS; U19
Type:
Nuclear speck, Nucleoplasm, Nucleus protein
Mass (Da):
28792
Number AA:
260
UniProt ID:
Q96CJ1
International Prot ID:
IPI00093988
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016607
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
R
V
L
K
L
G
E
S
F
E
K
Q
P
R
C
Site 2
T33
Q
P
R
C
A
F
H
T
V
R
Y
D
F
K
P
Site 3
S42
R
Y
D
F
K
P
A
S
I
D
T
S
S
E
G
Site 4
S46
K
P
A
S
I
D
T
S
S
E
G
Y
L
E
V
Site 5
S47
P
A
S
I
D
T
S
S
E
G
Y
L
E
V
G
Site 6
Y50
I
D
T
S
S
E
G
Y
L
E
V
G
E
G
E
Site 7
T62
E
G
E
Q
V
T
I
T
L
P
N
I
E
G
S
Site 8
T70
L
P
N
I
E
G
S
T
P
P
V
T
V
F
K
Site 9
T74
E
G
S
T
P
P
V
T
V
F
K
G
S
K
K
Site 10
Y83
F
K
G
S
K
K
P
Y
L
K
E
C
I
L
I
Site 11
T95
I
L
I
I
N
H
D
T
G
E
C
R
L
E
K
Site 12
S104
E
C
R
L
E
K
L
S
S
N
I
T
V
K
K
Site 13
S105
C
R
L
E
K
L
S
S
N
I
T
V
K
K
T
Site 14
T108
E
K
L
S
S
N
I
T
V
K
K
T
R
V
E
Site 15
T112
S
N
I
T
V
K
K
T
R
V
E
G
S
S
K
Site 16
S118
K
T
R
V
E
G
S
S
K
I
Q
Y
R
K
E
Site 17
Y122
E
G
S
S
K
I
Q
Y
R
K
E
Q
Q
Q
Q
Site 18
T137
Q
M
W
N
S
A
R
T
P
N
L
V
K
H
S
Site 19
S144
T
P
N
L
V
K
H
S
P
S
E
D
K
M
S
Site 20
S146
N
L
V
K
H
S
P
S
E
D
K
M
S
P
A
Site 21
S151
S
P
S
E
D
K
M
S
P
A
S
P
I
D
D
Site 22
S154
E
D
K
M
S
P
A
S
P
I
D
D
I
E
R
Site 23
S168
R
E
L
K
A
E
A
S
L
M
D
Q
M
S
S
Site 24
S174
A
S
L
M
D
Q
M
S
S
C
D
S
S
S
D
Site 25
S175
S
L
M
D
Q
M
S
S
C
D
S
S
S
D
S
Site 26
S178
D
Q
M
S
S
C
D
S
S
S
D
S
K
S
S
Site 27
S179
Q
M
S
S
C
D
S
S
S
D
S
K
S
S
S
Site 28
S180
M
S
S
C
D
S
S
S
D
S
K
S
S
S
S
Site 29
S182
S
C
D
S
S
S
D
S
K
S
S
S
S
S
S
Site 30
S184
D
S
S
S
D
S
K
S
S
S
S
S
S
S
E
Site 31
S185
S
S
S
D
S
K
S
S
S
S
S
S
S
E
D
Site 32
S186
S
S
D
S
K
S
S
S
S
S
S
S
E
D
S
Site 33
S187
S
D
S
K
S
S
S
S
S
S
S
E
D
S
S
Site 34
S188
D
S
K
S
S
S
S
S
S
S
E
D
S
S
S
Site 35
S189
S
K
S
S
S
S
S
S
S
E
D
S
S
S
D
Site 36
S190
K
S
S
S
S
S
S
S
E
D
S
S
S
D
S
Site 37
S193
S
S
S
S
S
E
D
S
S
S
D
S
E
D
E
Site 38
S194
S
S
S
S
E
D
S
S
S
D
S
E
D
E
D
Site 39
S195
S
S
S
E
D
S
S
S
D
S
E
D
E
D
C
Site 40
S197
S
E
D
S
S
S
D
S
E
D
E
D
C
K
S
Site 41
S204
S
E
D
E
D
C
K
S
S
T
S
D
T
G
N
Site 42
S205
E
D
E
D
C
K
S
S
T
S
D
T
G
N
C
Site 43
T209
C
K
S
S
T
S
D
T
G
N
C
V
S
G
H
Site 44
S214
S
D
T
G
N
C
V
S
G
H
P
T
M
T
Q
Site 45
T220
V
S
G
H
P
T
M
T
Q
Y
R
I
P
D
I
Site 46
Y222
G
H
P
T
M
T
Q
Y
R
I
P
D
I
D
A
Site 47
S230
R
I
P
D
I
D
A
S
H
N
R
F
R
D
N
Site 48
S238
H
N
R
F
R
D
N
S
G
L
L
M
N
T
L
Site 49
T244
N
S
G
L
L
M
N
T
L
R
N
D
L
Q
L
Site 50
S252
L
R
N
D
L
Q
L
S
E
S
G
S
D
S
D
Site 51
S254
N
D
L
Q
L
S
E
S
G
S
D
S
D
D
_
Site 52
S256
L
Q
L
S
E
S
G
S
D
S
D
D
_
_
_
Site 53
S258
L
S
E
S
G
S
D
S
D
D
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation