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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PLEKHB2
Full Name:
Pleckstrin homology domain-containing family B member 2
Alias:
Evectin-2
Type:
Mass (Da):
24736
Number AA:
222
UniProt ID:
Q96CS7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
S
G
W
L
L
R
Q
S
T
I
L
K
R
W
K
Site 2
T14
G
W
L
L
R
Q
S
T
I
L
K
R
W
K
K
Site 3
Y34
W
S
D
G
H
L
I
Y
Y
D
D
Q
T
R
Q
Site 4
Y35
S
D
G
H
L
I
Y
Y
D
D
Q
T
R
Q
N
Site 5
T65
T
G
Q
E
C
R
D
T
Q
P
P
D
G
K
S
Site 6
S88
C
R
D
G
K
T
I
S
L
C
A
E
S
T
D
Site 7
T109
F
T
L
Q
D
S
R
T
N
T
A
Y
V
G
S
Site 8
T111
L
Q
D
S
R
T
N
T
A
Y
V
G
S
A
V
Site 9
Y113
D
S
R
T
N
T
A
Y
V
G
S
A
V
M
T
Site 10
T123
S
A
V
M
T
D
E
T
S
V
V
S
S
P
P
Site 11
S124
A
V
M
T
D
E
T
S
V
V
S
S
P
P
P
Site 12
S128
D
E
T
S
V
V
S
S
P
P
P
Y
T
A
Y
Site 13
T133
V
S
S
P
P
P
Y
T
A
Y
A
A
P
A
P
Site 14
Y135
S
P
P
P
Y
T
A
Y
A
A
P
A
P
E
Q
Site 15
Y144
A
P
A
P
E
Q
A
Y
G
Y
G
P
Y
G
G
Site 16
Y146
A
P
E
Q
A
Y
G
Y
G
P
Y
G
G
A
Y
Site 17
Y149
Q
A
Y
G
Y
G
P
Y
G
G
A
Y
P
P
G
Site 18
Y153
Y
G
P
Y
G
G
A
Y
P
P
G
T
Q
V
V
Site 19
T157
G
G
A
Y
P
P
G
T
Q
V
V
Y
A
A
N
Site 20
Y161
P
P
G
T
Q
V
V
Y
A
A
N
G
Q
A
Y
Site 21
Y168
Y
A
A
N
G
Q
A
Y
A
V
P
Y
Q
Y
P
Site 22
Y172
G
Q
A
Y
A
V
P
Y
Q
Y
P
Y
A
G
L
Site 23
Y174
A
Y
A
V
P
Y
Q
Y
P
Y
A
G
L
Y
G
Site 24
Y176
A
V
P
Y
Q
Y
P
Y
A
G
L
Y
G
Q
Q
Site 25
Y194
Q
V
I
I
R
E
R
Y
R
D
N
D
S
D
L
Site 26
S199
E
R
Y
R
D
N
D
S
D
L
A
L
G
M
L
Site 27
S217
A
T
G
M
A
L
G
S
L
F
W
V
F
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation