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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA0443
Full Name:
G-protein coupled receptor-associated sorting protein 2
Alias:
FLJ37327; G protein-coupled receptor associated sorting protein 2; GASP2; Q96D09
Type:
Unknown function
Mass (Da):
93773
Number AA:
838
UniProt ID:
Q96D09
International Prot ID:
IPI00069232
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
T
G
A
E
I
E
P
S
A
Q
A
K
P
E
K
Site 2
T42
V
V
R
P
K
V
R
T
Q
A
T
T
G
A
R
Site 3
T46
K
V
R
T
Q
A
T
T
G
A
R
P
K
T
E
Site 4
T52
T
T
G
A
R
P
K
T
E
T
K
S
V
P
A
Site 5
T54
G
A
R
P
K
T
E
T
K
S
V
P
A
A
R
Site 6
S56
R
P
K
T
E
T
K
S
V
P
A
A
R
P
K
Site 7
T64
V
P
A
A
R
P
K
T
E
A
Q
A
M
S
G
Site 8
T76
M
S
G
A
R
P
K
T
E
V
Q
V
M
G
G
Site 9
T88
M
G
G
A
R
P
K
T
E
A
Q
G
I
T
G
Site 10
T100
I
T
G
A
R
P
K
T
D
A
R
A
V
G
G
Site 11
T112
V
G
G
A
R
S
K
T
D
A
K
A
I
P
G
Site 12
T136
W
A
Q
S
E
F
G
T
E
A
V
S
Q
A
E
Site 13
S140
E
F
G
T
E
A
V
S
Q
A
E
G
V
S
Q
Site 14
S160
W
P
L
A
T
A
E
S
G
S
V
T
K
S
K
Site 15
S162
L
A
T
A
E
S
G
S
V
T
K
S
K
G
L
Site 16
T164
T
A
E
S
G
S
V
T
K
S
K
G
L
S
M
Site 17
S166
E
S
G
S
V
T
K
S
K
G
L
S
M
D
R
Site 18
S170
V
T
K
S
K
G
L
S
M
D
R
E
L
V
N
Site 19
T182
L
V
N
V
D
A
E
T
F
P
G
T
Q
G
Q
Site 20
S206
G
E
E
T
N
M
G
S
W
C
Y
S
R
P
R
Site 21
Y209
T
N
M
G
S
W
C
Y
S
R
P
R
A
R
E
Site 22
S210
N
M
G
S
W
C
Y
S
R
P
R
A
R
E
E
Site 23
S219
P
R
A
R
E
E
A
S
N
E
S
G
F
W
S
Site 24
S226
S
N
E
S
G
F
W
S
A
D
E
T
S
T
A
Site 25
T230
G
F
W
S
A
D
E
T
S
T
A
S
S
F
W
Site 26
S231
F
W
S
A
D
E
T
S
T
A
S
S
F
W
T
Site 27
S235
D
E
T
S
T
A
S
S
F
W
T
G
E
E
T
Site 28
T238
S
T
A
S
S
F
W
T
G
E
E
T
S
V
R
Site 29
T242
S
F
W
T
G
E
E
T
S
V
R
S
W
P
R
Site 30
S243
F
W
T
G
E
E
T
S
V
R
S
W
P
R
E
Site 31
S246
G
E
E
T
S
V
R
S
W
P
R
E
E
S
N
Site 32
S252
R
S
W
P
R
E
E
S
N
T
R
S
R
H
R
Site 33
T254
W
P
R
E
E
S
N
T
R
S
R
H
R
A
K
Site 34
S256
R
E
E
S
N
T
R
S
R
H
R
A
K
H
Q
Site 35
T264
R
H
R
A
K
H
Q
T
N
P
R
S
R
P
R
Site 36
S268
K
H
Q
T
N
P
R
S
R
P
R
S
K
Q
E
Site 37
S272
N
P
R
S
R
P
R
S
K
Q
E
A
Y
V
D
Site 38
Y277
P
R
S
K
Q
E
A
Y
V
D
S
W
S
G
S
Site 39
S280
K
Q
E
A
Y
V
D
S
W
S
G
S
E
D
E
Site 40
S282
E
A
Y
V
D
S
W
S
G
S
E
D
E
A
S
Site 41
S284
Y
V
D
S
W
S
G
S
E
D
E
A
S
N
P
Site 42
S289
S
G
S
E
D
E
A
S
N
P
F
S
F
W
V
Site 43
S293
D
E
A
S
N
P
F
S
F
W
V
G
E
N
T
Site 44
T320
N
I
R
S
K
L
R
T
N
R
E
D
C
F
E
Site 45
S328
N
R
E
D
C
F
E
S
E
S
E
D
E
F
Y
Site 46
S330
E
D
C
F
E
S
E
S
E
D
E
F
Y
K
Q
Site 47
Y335
S
E
S
E
D
E
F
Y
K
Q
S
W
V
L
P
Site 48
S348
L
P
G
E
E
A
N
S
R
F
R
H
R
D
K
Site 49
T360
R
D
K
E
D
P
N
T
A
L
K
L
R
A
Q
Site 50
S372
R
A
Q
K
D
V
D
S
D
R
V
K
Q
E
P
Site 51
S398
F
W
A
E
K
E
A
S
L
E
G
G
A
S
A
Site 52
S404
A
S
L
E
G
G
A
S
A
I
C
E
S
E
P
Site 53
S409
G
A
S
A
I
C
E
S
E
P
G
T
E
E
G
Site 54
T413
I
C
E
S
E
P
G
T
E
E
G
A
I
G
G
Site 55
Y423
G
A
I
G
G
S
A
Y
W
A
E
E
K
S
S
Site 56
S430
Y
W
A
E
E
K
S
S
L
G
A
V
A
R
E
Site 57
S443
R
E
E
A
K
P
E
S
E
E
E
A
I
F
G
Site 58
Y469
D
L
N
P
C
P
V
Y
K
V
S
D
R
F
R
Site 59
S472
P
C
P
V
Y
K
V
S
D
R
F
R
D
A
A
Site 60
S485
A
A
E
E
L
N
A
S
S
R
P
Q
T
W
D
Site 61
T490
N
A
S
S
R
P
Q
T
W
D
E
V
T
V
E
Site 62
T495
P
Q
T
W
D
E
V
T
V
E
F
K
P
G
L
Site 63
S510
F
H
G
V
G
F
R
S
T
S
P
F
G
I
P
Site 64
T511
H
G
V
G
F
R
S
T
S
P
F
G
I
P
E
Site 65
S512
G
V
G
F
R
S
T
S
P
F
G
I
P
E
E
Site 66
S534
K
P
K
N
L
E
L
S
P
E
G
E
E
Q
E
Site 67
S542
P
E
G
E
E
Q
E
S
L
L
Q
P
D
Q
P
Site 68
S550
L
L
Q
P
D
Q
P
S
P
E
F
T
F
Q
Y
Site 69
T554
D
Q
P
S
P
E
F
T
F
Q
Y
D
P
S
Y
Site 70
Y557
S
P
E
F
T
F
Q
Y
D
P
S
Y
R
S
V
Site 71
S560
F
T
F
Q
Y
D
P
S
Y
R
S
V
R
E
I
Site 72
Y561
T
F
Q
Y
D
P
S
Y
R
S
V
R
E
I
R
Site 73
S563
Q
Y
D
P
S
Y
R
S
V
R
E
I
R
E
H
Site 74
S576
E
H
L
R
A
R
E
S
A
E
S
E
S
W
S
Site 75
S579
R
A
R
E
S
A
E
S
E
S
W
S
C
S
C
Site 76
S581
R
E
S
A
E
S
E
S
W
S
C
S
C
I
Q
Site 77
S583
S
A
E
S
E
S
W
S
C
S
C
I
Q
C
E
Site 78
S595
Q
C
E
L
K
I
G
S
E
E
F
E
E
F
L
Site 79
S625
K
I
A
M
G
M
R
S
A
S
Q
F
T
R
D
Site 80
S627
A
M
G
M
R
S
A
S
Q
F
T
R
D
F
I
Site 81
S637
T
R
D
F
I
R
D
S
G
V
V
S
L
I
E
Site 82
Y649
L
I
E
T
L
L
N
Y
P
S
S
R
V
R
T
Site 83
S651
E
T
L
L
N
Y
P
S
S
R
V
R
T
S
F
Site 84
S652
T
L
L
N
Y
P
S
S
R
V
R
T
S
F
L
Site 85
T656
Y
P
S
S
R
V
R
T
S
F
L
E
N
M
I
Site 86
S657
P
S
S
R
V
R
T
S
F
L
E
N
M
I
H
Site 87
S690
C
E
E
T
L
A
H
S
V
D
S
L
E
Q
L
Site 88
T707
I
R
M
L
R
H
L
T
M
T
I
D
Y
H
T
Site 89
T728
S
G
F
L
S
L
L
T
T
A
N
A
R
T
K
Site 90
S762
L
F
S
A
K
A
L
S
I
F
V
G
L
F
N
Site 91
S793
N
I
S
N
I
I
K
S
G
K
M
S
L
I
D
Site 92
S797
I
I
K
S
G
K
M
S
L
I
D
D
D
F
S
Site 93
S810
F
S
L
E
P
L
I
S
A
F
R
E
F
E
E
Site 94
S838
D
P
E
V
G
Q
Q
S
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation