PhosphoNET

           
Protein Info 
   
Short Name:  CRACM1
Full Name:  Calcium release-activated calcium channel protein 1
Alias:  Protein orai-1; Transmembrane protein 142A
Type:  Channel, calcium
Mass (Da):  32668
Number AA:  301
UniProt ID:  Q96D31
International Prot ID:  IPI00303699
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005887     Uniprot OncoNet
Molecular Function:  GO:0005509  GO:0005515  GO:0015279 PhosphoSite+ KinaseNET
Biological Process:  GO:0006816  GO:0006955  GO:0051928 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S10PEPAPPPSRSSPELP
Site 2S12PAPPPSRSSPELPPS
Site 3S13APPPSRSSPELPPSG
Site 4S19SSPELPPSGGSTTSG
Site 5S22ELPPSGGSTTSGSRR
Site 6T23LPPSGGSTTSGSRRS
Site 7S25PSGGSTTSGSRRSRR
Site 8S27GGSTTSGSRRSRRRS
Site 9S30TTSGSRRSRRRSGDG
Site 10S34SRRSRRRSGDGEPPG
Site 11S48GAPPPPPSAVTYPDW
Site 12Y52PPPSAVTYPDWIGQS
Site 13Y60PDWIGQSYSEVMSLN
Site 14S61DWIGQSYSEVMSLNE
Site 15S65QSYSEVMSLNEHSMQ
Site 16S75EHSMQALSWRKLYLS
Site 17Y80ALSWRKLYLSRAKLK
Site 18S82SWRKLYLSRAKLKAS
Site 19S89SRAKLKASSRTSALL
Site 20S90RAKLKASSRTSALLS
Site 21Y115QLDADHDYPPGLLIA
Site 22S159SNVHNLNSVKESPHE
Site 23S163NLNSVKESPHERMHR
Site 24T212QPGQPRPTSKPPASG
Site 25S213PGQPRPTSKPPASGA
Site 26S218PTSKPPASGAAANVS
Site 27S260FAVHFYRSLVSHKTD
Site 28T266RSLVSHKTDRQFQEL
Site 29T295HRGDHPLTPGSHYA 
Site 30S298DHPLTPGSHYA____
Site 31Y300PLTPGSHYA______
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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