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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ADCK4
Full Name:
Uncharacterized aarF domain-containing protein kinase 4
Alias:
aarF domain containing kinase 4; COQ8; FLJ12229; Similar to RIKEN cDNA 0610012P18 gene
Type:
Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.-; EC 2.7.-.-;
ATYPICAL
group; ABC1 family; ABC1-A subfamily
Mass (Da):
60069
Number AA:
544
UniProt ID:
Q96D53
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0004674
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
V
G
G
L
L
R
G
T
G
G
Q
L
G
Q
T
Site 2
T19
T
G
G
Q
L
G
Q
T
V
G
W
P
C
G
A
Site 3
Y46
G
S
W
A
Q
K
F
Y
Q
D
G
P
G
R
G
Site 4
T70
R
E
A
R
P
R
K
T
P
R
P
Q
L
S
D
Site 5
S76
K
T
P
R
P
Q
L
S
D
R
S
R
E
R
K
Site 6
S79
R
P
Q
L
S
D
R
S
R
E
R
K
V
P
A
Site 7
S87
R
E
R
K
V
P
A
S
R
I
S
R
L
A
N
Site 8
S90
K
V
P
A
S
R
I
S
R
L
A
N
F
G
G
Site 9
S114
L
A
E
M
A
K
K
S
M
P
G
G
R
L
Q
Site 10
S122
M
P
G
G
R
L
Q
S
E
G
G
S
G
L
D
Site 11
S126
R
L
Q
S
E
G
G
S
G
L
D
S
S
P
F
Site 12
S130
E
G
G
S
G
L
D
S
S
P
F
L
S
E
A
Site 13
S131
G
G
S
G
L
D
S
S
P
F
L
S
E
A
N
Site 14
S135
L
D
S
S
P
F
L
S
E
A
N
A
E
R
I
Site 15
S166
M
L
S
I
Q
D
N
S
F
I
S
P
Q
L
Q
Site 16
S169
I
Q
D
N
S
F
I
S
P
Q
L
Q
H
I
F
Site 17
S209
D
W
Q
A
K
V
A
S
L
E
E
V
P
F
A
Site 18
T232
Q
G
L
L
R
D
G
T
E
V
A
V
K
I
Q
Site 19
S246
Q
Y
P
G
I
A
Q
S
I
Q
S
D
V
Q
N
Site 20
S273
A
G
L
F
A
E
Q
S
L
Q
A
L
Q
Q
E
Site 21
Y287
E
L
A
W
E
C
D
Y
R
R
E
A
A
C
A
Site 22
S339
L
D
Q
C
Q
G
L
S
Q
D
L
R
N
Q
I
Site 23
Y375
P
N
W
A
N
F
L
Y
D
A
S
S
H
Q
V
Site 24
S379
N
F
L
Y
D
A
S
S
H
Q
V
T
L
L
D
Site 25
T383
D
A
S
S
H
Q
V
T
L
L
D
F
G
A
S
Site 26
Y401
G
T
E
F
T
D
H
Y
I
E
V
V
K
A
A
Site 27
S420
R
D
C
V
L
Q
K
S
R
D
L
K
F
L
T
Site 28
T427
S
R
D
L
K
F
L
T
G
F
E
T
K
A
F
Site 29
T431
K
F
L
T
G
F
E
T
K
A
F
S
D
A
H
Site 30
S435
G
F
E
T
K
A
F
S
D
A
H
V
E
A
V
Site 31
T451
I
L
G
E
P
F
A
T
Q
G
P
Y
D
F
G
Site 32
Y455
P
F
A
T
Q
G
P
Y
D
F
G
S
G
E
T
Site 33
S459
Q
G
P
Y
D
F
G
S
G
E
T
A
R
R
I
Site 34
Y516
R
D
L
F
Q
D
T
Y
H
R
Y
W
A
S
R
Site 35
Y519
F
Q
D
T
Y
H
R
Y
W
A
S
R
Q
P
D
Site 36
T529
S
R
Q
P
D
A
A
T
A
G
S
L
P
T
K
Site 37
S532
P
D
A
A
T
A
G
S
L
P
T
K
G
D
S
Site 38
S539
S
L
P
T
K
G
D
S
W
V
D
P
S
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation