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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C18orf8
Full Name:
Uncharacterized protein C18orf8
Alias:
Chromosome 18 open reading frame 8; Colon cancer associated protein Mic1; Colon cancer-associated Mic1; HsT2591; MIC1; Mic-1
Type:
Unknown function
Mass (Da):
74975
Number AA:
657
UniProt ID:
Q96DM3
International Prot ID:
IPI00149964
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y7
_
M
G
E
E
D
Y
Y
L
E
L
C
E
R
P
Site 2
S58
P
D
D
R
N
P
I
S
F
R
M
D
D
K
G
Site 3
Y102
P
D
N
S
Q
L
E
Y
T
Q
E
C
K
T
K
Site 4
S143
Q
V
L
P
E
K
R
S
L
K
L
L
K
S
H
Site 5
S149
R
S
L
K
L
L
K
S
H
N
L
N
V
N
W
Site 6
T186
P
F
H
F
R
A
G
T
M
S
K
L
P
K
F
Site 7
S188
H
F
R
A
G
T
M
S
K
L
P
K
F
E
I
Site 8
S203
E
L
P
A
A
P
K
S
T
K
P
S
L
S
E
Site 9
S207
A
P
K
S
T
K
P
S
L
S
E
R
D
I
A
Site 10
S209
K
S
T
K
P
S
L
S
E
R
D
I
A
M
A
Site 11
S231
V
L
F
L
R
H
H
S
R
T
S
N
S
T
G
Site 12
T233
F
L
R
H
H
S
R
T
S
N
S
T
G
A
E
Site 13
S234
L
R
H
H
S
R
T
S
N
S
T
G
A
E
V
Site 14
T237
H
S
R
T
S
N
S
T
G
A
E
V
V
L
Y
Site 15
Y244
T
G
A
E
V
V
L
Y
H
L
P
R
E
G
A
Site 16
T284
V
H
H
Q
D
T
E
T
S
V
I
F
D
I
K
Site 17
S299
L
R
G
E
F
D
G
S
V
T
F
H
H
P
V
Site 18
Y315
P
A
R
S
I
Q
P
Y
Q
I
P
I
T
G
P
Site 19
S327
T
G
P
A
A
V
T
S
Q
S
P
V
P
C
K
Site 20
S399
S
V
C
S
Q
M
L
S
E
S
D
R
A
S
L
Site 21
S401
C
S
Q
M
L
S
E
S
D
R
A
S
L
P
V
Site 22
Y423
L
N
H
E
Y
K
K
Y
L
D
A
E
Q
S
Y
Site 23
S439
M
A
V
E
A
G
Q
S
R
S
S
P
L
L
K
Site 24
S442
E
A
G
Q
S
R
S
S
P
L
L
K
R
P
V
Site 25
Y524
M
L
H
Q
F
L
Q
Y
H
V
L
S
D
S
K
Site 26
Y544
L
L
S
L
E
S
F
Y
P
P
A
H
Q
L
S
Site 27
S551
Y
P
P
A
H
Q
L
S
L
D
M
L
K
R
L
Site 28
S559
L
D
M
L
K
R
L
S
T
A
N
D
E
I
V
Site 29
T560
D
M
L
K
R
L
S
T
A
N
D
E
I
V
E
Site 30
S592
I
G
G
H
D
N
I
S
A
R
K
F
L
D
A
Site 31
Y610
T
E
D
N
M
L
F
Y
T
I
F
R
F
F
E
Site 32
S626
R
N
Q
R
L
R
G
S
P
N
F
T
P
G
E
Site 33
T630
L
R
G
S
P
N
F
T
P
G
E
H
C
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation