PhosphoNET

           
Protein Info 
   
Short Name:  MBD6
Full Name:  Methyl-CpG-binding domain protein 6
Alias:  Methyl-CpG-binding protein MBD6
Type: 
Mass (Da):  101201
Number AA:  1003
UniProt ID:  Q96DN6
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y36VREGAVLYISPSGTE
Site 2T42LYISPSGTELSSLEQ
Site 3S45SPSGTELSSLEQTRS
Site 4S46PSGTELSSLEQTRSY
Site 5T50ELSSLEQTRSYLLSD
Site 6S52SSLEQTRSYLLSDGT
Site 7Y53SLEQTRSYLLSDGTC
Site 8S56QTRSYLLSDGTCKCG
Site 9S93GAGVGPASEEDMTKL
Site 10T98PASEEDMTKLCNHRR
Site 11T112RKAVAMATLYRSMET
Site 12Y114AVAMATLYRSMETTC
Site 13T120LYRSMETTCSHSSPG
Site 14S122RSMETTCSHSSPGEG
Site 15S124METTCSHSSPGEGAS
Site 16S125ETTCSHSSPGEGASP
Site 17S131SSPGEGASPQMFHTV
Site 18T137ASPQMFHTVSPGPPS
Site 19S139PQMFHTVSPGPPSAR
Site 20S144TVSPGPPSARPPCRV
Site 21T154PPCRVPPTTPLNGGP
Site 22T155PCRVPPTTPLNGGPG
Site 23S163PLNGGPGSLPPEPPS
Site 24S170SLPPEPPSVSQAFPT
Site 25S172PPEPPSVSQAFPTLA
Site 26S195RLADPVPSGGSSSPR
Site 27S198DPVPSGGSSSPRFLP
Site 28S199PVPSGGSSSPRFLPR
Site 29S200VPSGGSSSPRFLPRG
Site 30S211LPRGNAPSPAPPPPP
Site 31S221PPPPPAISLNAPSYN
Site 32Y227ISLNAPSYNWGAALR
Site 33S235NWGAALRSSLVPSDL
Site 34S240LRSSLVPSDLGSPPA
Site 35S244LVPSDLGSPPAPHAS
Site 36S251SPPAPHASSSPPSDP
Site 37S252PPAPHASSSPPSDPP
Site 38S253PAPHASSSPPSDPPL
Site 39S256HASSSPPSDPPLFHC
Site 40S264DPPLFHCSDALTPPP
Site 41T268FHCSDALTPPPLPPS
Site 42S275TPPPLPPSNNLPAHP
Site 43S286PAHPGPASQPPVSSA
Site 44S291PASQPPVSSATMHLP
Site 45S292ASQPPVSSATMHLPL
Site 46T309GPLGGAPTVEGPGAP
Site 47S339HPPLPPPSTLQGRRP
Site 48T340PPLPPPSTLQGRRPR
Site 49S352RPRAQAPSASHSSSL
Site 50S354RAQAPSASHSSSLRP
Site 51S356QAPSASHSSSLRPSQ
Site 52S357APSASHSSSLRPSQR
Site 53S358PSASHSSSLRPSQRR
Site 54S362HSSSLRPSQRRPRRP
Site 55T371RRPRRPPTVFRLLEG
Site 56T383LEGRGPQTPRRSRPR
Site 57S387GPQTPRRSRPRAPAP
Site 58S400APVPQPFSLPEPSQP
Site 59S405PFSLPEPSQPILPSV
Site 60T420LSLLGLPTPGPSHSD
Site 61S424GLPTPGPSHSDGSFN
Site 62S426PTPGPSHSDGSFNLL
Site 63S429GPSHSDGSFNLLGSD
Site 64S435GSFNLLGSDAHLPPP
Site 65T444AHLPPPPTLSSGSPP
Site 66S446LPPPPTLSSGSPPQP
Site 67S447PPPPTLSSGSPPQPR
Site 68S449PPTLSSGSPPQPRHP
Site 69S460PRHPIQPSLPGTTSG
Site 70T464IQPSLPGTTSGSLSS
Site 71S466PSLPGTTSGSLSSVP
Site 72S470GTTSGSLSSVPGAPA
Site 73S471TTSGSLSSVPGAPAP
Site 74S489SKAPVVPSPVLQSPS
Site 75S494VPSPVLQSPSEGLGM
Site 76S496SPVLQSPSEGLGMGA
Site 77S522GEAFPFPSPEQGLAL
Site 78S553SLGQPPPSPLLNHSL
Site 79T565HSLFGVLTGGGGQPP
Site 80S608SLLPPPPSDLLPPPS
Site 81S615SDLLPPPSAPPSNLL
Site 82S641TAGDGEGSAEGAGGP
Site 83S649AEGAGGPSGEPFSGL
Site 84S654GPSGEPFSGLGDLSP
Site 85S689AATLDPPSGTPPQPC
Site 86T691TLDPPSGTPPQPCVL
Site 87S699PPQPCVLSAPQPGPP
Site 88T707APQPGPPTSSVTTAT
Site 89S708PQPGPPTSSVTTATT
Site 90S709QPGPPTSSVTTATTD
Site 91T712PPTSSVTTATTDPGA
Site 92T714TSSVTTATTDPGASS
Site 93T715SSVTTATTDPGASSL
Site 94S721TTDPGASSLGKAPSN
Site 95S727SSLGKAPSNSGRPPQ
Site 96S729LGKAPSNSGRPPQLL
Site 97S753GDLSSLTSSPGALPS
Site 98S760SSPGALPSLLQPPGP
Site 99S788GGAPPPLSEASSPLA
Site 100S817APCLPPESPASALEP
Site 101S820LPPESPASALEPEPA
Site 102S832EPARPPLSALAPPHG
Site 103S840ALAPPHGSPDPPVPE
Site 104T850PPVPELLTGRGSGKR
Site 105S854ELLTGRGSGKRGRRG
Site 106S882ARGRKPGSRREPGRL
Site 107S936PPPPGPHSEDLKVPP
Site 108S949PPGVVRKSRRGRRRK
Site 109Y957RRGRRRKYNPTRNSN
Site 110T960RRRKYNPTRNSNSSR
Site 111S963KYNPTRNSNSSRQDI
Site 112S965NPTRNSNSSRQDITL
Site 113S966PTRNSNSSRQDITLE
Site 114T971NSSRQDITLEPSPTA
Site 115S975QDITLEPSPTARAAV
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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