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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RSPRY1
Full Name:
RING finger and SPRY domain-containing protein 1
Alias:
Type:
Mass (Da):
64180
Number AA:
576
UniProt ID:
Q96DX4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S50
S
C
I
C
R
D
D
S
G
T
D
D
S
V
D
Site 2
T52
I
C
R
D
D
S
G
T
D
D
S
V
D
T
Q
Site 3
S55
D
D
S
G
T
D
D
S
V
D
T
Q
Q
Q
Q
Site 4
T70
A
E
N
S
A
V
P
T
A
D
T
R
S
Q
P
Site 5
S75
V
P
T
A
D
T
R
S
Q
P
R
D
P
V
R
Site 6
Y123
D
N
D
Q
E
P
P
Y
S
M
I
T
L
H
E
Site 7
T134
T
L
H
E
M
A
E
T
D
E
G
W
L
D
V
Site 8
S193
G
E
V
A
C
Q
D
S
S
H
P
A
K
H
R
Site 9
S194
E
V
A
C
Q
D
S
S
H
P
A
K
H
R
N
Site 10
T202
H
P
A
K
H
R
N
T
S
A
V
L
G
C
L
Site 11
S203
P
A
K
H
R
N
T
S
A
V
L
G
C
L
A
Site 12
T262
Q
T
S
E
N
K
L
T
I
S
E
S
S
I
S
Site 13
S264
S
E
N
K
L
T
I
S
E
S
S
I
S
D
R
Site 14
S266
N
K
L
T
I
S
E
S
S
I
S
D
R
L
V
Site 15
S267
K
L
T
I
S
E
S
S
I
S
D
R
L
V
T
Site 16
S269
T
I
S
E
S
S
I
S
D
R
L
V
T
L
E
Site 17
T274
S
I
S
D
R
L
V
T
L
E
S
W
A
N
D
Site 18
S277
D
R
L
V
T
L
E
S
W
A
N
D
P
D
Y
Site 19
Y284
S
W
A
N
D
P
D
Y
L
K
R
Q
V
G
F
Site 20
T309
L
K
E
G
R
Q
L
T
Y
E
K
V
N
L
S
Site 21
Y310
K
E
G
R
Q
L
T
Y
E
K
V
N
L
S
S
Site 22
S316
T
Y
E
K
V
N
L
S
S
I
R
A
M
L
N
Site 23
S317
Y
E
K
V
N
L
S
S
I
R
A
M
L
N
S
Site 24
S324
S
I
R
A
M
L
N
S
N
D
V
S
E
Y
L
Site 25
S328
M
L
N
S
N
D
V
S
E
Y
L
K
I
S
P
Site 26
Y330
N
S
N
D
V
S
E
Y
L
K
I
S
P
H
G
Site 27
S334
V
S
E
Y
L
K
I
S
P
H
G
L
E
A
R
Site 28
S345
L
E
A
R
C
D
A
S
S
F
E
S
V
R
C
Site 29
S346
E
A
R
C
D
A
S
S
F
E
S
V
R
C
T
Site 30
Y390
K
F
L
N
H
E
G
Y
G
I
G
D
D
E
Y
Site 31
Y397
Y
G
I
G
D
D
E
Y
S
C
A
Y
D
G
C
Site 32
Y410
G
C
R
Q
L
I
W
Y
N
A
R
S
K
P
H
Site 33
S456
P
P
E
K
Q
V
F
S
S
T
V
S
G
F
F
Site 34
S457
P
E
K
Q
V
F
S
S
T
V
S
G
F
F
A
Site 35
Y471
A
A
A
S
F
M
S
Y
Q
Q
C
E
F
N
F
Site 36
Y485
F
G
A
K
P
F
K
Y
P
P
S
M
K
F
S
Site 37
S488
K
P
F
K
Y
P
P
S
M
K
F
S
T
F
N
Site 38
T493
P
P
S
M
K
F
S
T
F
N
D
Y
A
F
L
Site 39
Y497
K
F
S
T
F
N
D
Y
A
F
L
T
A
E
E
Site 40
S567
L
C
R
K
E
I
V
S
R
I
R
Q
I
S
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation