KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ELP4
Full Name:
Elongator complex protein 4
Alias:
PAX6 neighbor gene protein
Type:
Mass (Da):
46588
Number AA:
424
UniProt ID:
Q96EB1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T20
S
T
G
S
A
V
A
T
A
S
K
S
N
V
T
Site 2
S24
A
V
A
T
A
S
K
S
N
V
T
S
F
Q
R
Site 3
S28
A
S
K
S
N
V
T
S
F
Q
R
R
G
P
R
Site 4
S37
Q
R
R
G
P
R
A
S
V
T
N
D
S
G
P
Site 5
T39
R
G
P
R
A
S
V
T
N
D
S
G
P
R
L
Site 6
S42
R
A
S
V
T
N
D
S
G
P
R
L
V
S
I
Site 7
S48
D
S
G
P
R
L
V
S
I
A
G
T
R
P
S
Site 8
T52
R
L
V
S
I
A
G
T
R
P
S
V
R
N
G
Site 9
S55
S
I
A
G
T
R
P
S
V
R
N
G
Q
L
L
Site 10
Y91
L
L
I
E
E
D
K
Y
N
I
Y
S
P
L
L
Site 11
Y94
E
E
D
K
Y
N
I
Y
S
P
L
L
F
K
Y
Site 12
Y147
K
E
F
D
E
D
V
Y
N
H
K
T
P
E
S
Site 13
T151
E
D
V
Y
N
H
K
T
P
E
S
N
I
K
M
Site 14
S176
K
M
E
I
G
P
V
S
S
S
R
F
G
H
Y
Site 15
S177
M
E
I
G
P
V
S
S
S
R
F
G
H
Y
Y
Site 16
S178
E
I
G
P
V
S
S
S
R
F
G
H
Y
Y
D
Site 17
Y183
S
S
S
R
F
G
H
Y
Y
D
A
S
K
R
M
Site 18
Y184
S
S
R
F
G
H
Y
Y
D
A
S
K
R
M
P
Site 19
S211
F
L
P
E
K
I
S
S
T
L
K
V
E
P
C
Site 20
T212
L
P
E
K
I
S
S
T
L
K
V
E
P
C
S
Site 21
S219
T
L
K
V
E
P
C
S
L
T
P
G
Y
T
K
Site 22
T221
K
V
E
P
C
S
L
T
P
G
Y
T
K
L
L
Site 23
Y236
Q
F
I
Q
N
I
I
Y
E
E
G
F
D
G
S
Site 24
S243
Y
E
E
G
F
D
G
S
N
P
Q
K
K
Q
R
Site 25
S280
E
N
G
G
N
S
H
S
L
T
K
F
L
Y
V
Site 26
T282
G
G
N
S
H
S
L
T
K
F
L
Y
V
L
R
Site 27
S333
G
L
E
S
F
I
G
S
E
R
E
T
N
P
L
Site 28
T337
F
I
G
S
E
R
E
T
N
P
L
Y
K
D
Y
Site 29
Y341
E
R
E
T
N
P
L
Y
K
D
Y
H
G
L
I
Site 30
Y344
T
N
P
L
Y
K
D
Y
H
G
L
I
H
I
R
Site 31
S364
N
N
L
I
C
D
E
S
D
V
K
D
L
A
F
Site 32
S390
L
H
L
P
P
D
L
S
D
T
V
S
R
S
S
Site 33
T392
L
P
P
D
L
S
D
T
V
S
R
S
S
K
M
Site 34
S394
P
D
L
S
D
T
V
S
R
S
S
K
M
D
L
Site 35
S396
L
S
D
T
V
S
R
S
S
K
M
D
L
A
E
Site 36
S397
S
D
T
V
S
R
S
S
K
M
D
L
A
E
S
Site 37
S404
S
K
M
D
L
A
E
S
A
K
R
L
G
P
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation