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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MTMR8
Full Name:
Myotubularin-related protein 8
Alias:
EC 3.1.3.-; Flj20126; Mtmr8; Myotubularin related protein 8
Type:
Nucleus, Nuclear envelope protein
Mass (Da):
78919
Number AA:
704
UniProt ID:
Q96EF0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005635
Uniprot
OncoNet
Molecular Function:
GO:0004725
PhosphoSite+
KinaseNET
Biological Process:
GO:0016311
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y18
N
V
K
L
V
D
R
Y
V
S
K
K
P
A
N
Site 2
S20
K
L
V
D
R
Y
V
S
K
K
P
A
N
G
I
Site 3
T48
S
G
A
A
R
K
E
T
W
I
A
L
H
H
I
Site 4
T71
T
S
L
G
C
P
L
T
L
R
C
K
N
F
R
Site 5
S101
Y
I
S
L
L
K
L
S
Q
P
A
L
P
E
D
Site 6
Y110
P
A
L
P
E
D
L
Y
A
F
S
Y
N
P
K
Site 7
S113
P
E
D
L
Y
A
F
S
Y
N
P
K
S
S
K
Site 8
Y114
E
D
L
Y
A
F
S
Y
N
P
K
S
S
K
E
Site 9
S118
A
F
S
Y
N
P
K
S
S
K
E
M
R
E
S
Site 10
S125
S
S
K
E
M
R
E
S
G
W
K
L
I
D
P
Site 11
T147
G
I
P
N
R
N
W
T
I
T
D
A
N
R
N
Site 12
Y155
I
T
D
A
N
R
N
Y
E
I
C
S
T
Y
P
Site 13
T160
R
N
Y
E
I
C
S
T
Y
P
P
E
I
V
V
Site 14
Y161
N
Y
E
I
C
S
T
Y
P
P
E
I
V
V
P
Site 15
S180
L
G
T
V
V
G
S
S
K
F
R
S
K
E
R
Site 16
S184
V
G
S
S
K
F
R
S
K
E
R
V
P
V
L
Site 17
S192
K
E
R
V
P
V
L
S
Y
L
Y
K
E
N
N
Site 18
Y193
E
R
V
P
V
L
S
Y
L
Y
K
E
N
N
A
Site 19
T214
Q
P
L
S
G
F
Y
T
R
C
V
D
D
E
L
Site 20
S227
E
L
L
L
E
A
I
S
Q
T
N
P
G
S
Q
Site 21
T229
L
L
E
A
I
S
Q
T
N
P
G
S
Q
F
M
Site 22
S233
I
S
Q
T
N
P
G
S
Q
F
M
Y
V
V
D
Site 23
Y237
N
P
G
S
Q
F
M
Y
V
V
D
T
R
P
K
Site 24
Y257
N
R
A
A
G
K
G
Y
E
N
E
D
N
Y
A
Site 25
Y263
G
Y
E
N
E
D
N
Y
A
N
I
R
F
R
F
Site 26
S298
E
L
K
T
P
T
M
S
E
F
L
S
G
L
E
Site 27
S302
P
T
M
S
E
F
L
S
G
L
E
S
S
G
W
Site 28
S306
E
F
L
S
G
L
E
S
S
G
W
L
R
H
I
Site 29
S392
C
G
H
L
D
G
D
S
K
E
V
S
P
I
F
Site 30
S396
D
G
D
S
K
E
V
S
P
I
F
T
Q
F
L
Site 31
Y453
D
R
E
D
L
R
V
Y
E
K
T
H
S
V
W
Site 32
T456
D
L
R
V
Y
E
K
T
H
S
V
W
P
F
L
Site 33
Y475
P
D
F
R
N
P
L
Y
K
G
F
T
M
Y
G
Site 34
T479
N
P
L
Y
K
G
F
T
M
Y
G
V
L
N
P
Site 35
T488
Y
G
V
L
N
P
S
T
V
P
Y
N
I
Q
F
Site 36
S512
K
G
L
Q
P
K
Q
S
M
L
E
S
L
L
E
Site 37
S516
P
K
Q
S
M
L
E
S
L
L
E
I
K
K
Q
Site 38
T529
K
Q
R
A
M
L
E
T
D
V
H
E
L
E
K
Site 39
T550
E
P
P
E
E
I
C
T
C
S
Q
L
G
N
I
Site 40
S559
S
Q
L
G
N
I
L
S
Q
H
L
G
S
P
L
Site 41
T567
Q
H
L
G
S
P
L
T
N
P
L
G
F
M
G
Site 42
T581
G
I
N
G
D
L
N
T
L
M
E
N
G
T
L
Site 43
T587
N
T
L
M
E
N
G
T
L
S
R
E
G
G
L
Site 44
S589
L
M
E
N
G
T
L
S
R
E
G
G
L
R
A
Site 45
S603
A
Q
M
D
Q
V
K
S
Q
G
A
D
L
H
H
Site 46
S673
I
S
G
N
L
G
I
S
E
A
R
G
F
S
G
Site 47
T695
T
G
I
S
K
A
S
T
K
E
A
D
Y
S
K
Site 48
Y700
A
S
T
K
E
A
D
Y
S
K
H
Q
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation