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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PHF21B
Full Name:
PHD finger protein 21B
Alias:
PF21B; PHD finger 21B
Type:
Uncharacterized protein
Mass (Da):
57455
Number AA:
531
UniProt ID:
Q96EK2
International Prot ID:
IPI00738578
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S37
Q
P
R
I
A
A
L
S
D
K
Q
A
L
G
T
Site 2
S57
V
T
G
P
Q
V
S
S
L
Q
R
L
A
G
Q
Site 3
T76
L
P
Q
V
R
P
K
T
L
I
P
D
S
L
P
Site 4
S81
P
K
T
L
I
P
D
S
L
P
V
A
P
G
R
Site 5
T97
R
P
P
K
Q
P
P
T
F
Q
K
A
T
V
V
Site 6
S110
V
V
S
V
K
N
P
S
P
A
L
P
T
A
N
Site 7
T119
A
L
P
T
A
N
N
T
V
S
H
V
P
A
P
Site 8
S121
P
T
A
N
N
T
V
S
H
V
P
A
P
G
S
Site 9
S128
S
H
V
P
A
P
G
S
Q
P
Q
A
L
A
E
Site 10
S195
K
P
P
P
R
L
L
S
S
P
H
P
A
T
H
Site 11
S196
P
P
P
R
L
L
S
S
P
H
P
A
T
H
H
Site 12
T201
L
S
S
P
H
P
A
T
H
H
C
P
L
H
P
Site 13
S209
H
H
C
P
L
H
P
S
S
L
P
L
T
P
P
Site 14
S210
H
C
P
L
H
P
S
S
L
P
L
T
P
P
S
Site 15
T214
H
P
S
S
L
P
L
T
P
P
S
P
S
L
S
Site 16
S217
S
L
P
L
T
P
P
S
P
S
L
S
P
S
P
Site 17
S219
P
L
T
P
P
S
P
S
L
S
P
S
P
L
H
Site 18
S221
T
P
P
S
P
S
L
S
P
S
P
L
H
G
I
Site 19
S223
P
S
P
S
L
S
P
S
P
L
H
G
I
F
Q
Site 20
S244
Q
V
Q
T
Q
P
E
S
T
A
E
S
R
P
P
Site 21
S248
Q
P
E
S
T
A
E
S
R
P
P
T
E
E
P
Site 22
T252
T
A
E
S
R
P
P
T
E
E
P
S
Q
G
A
Site 23
S256
R
P
P
T
E
E
P
S
Q
G
A
Q
A
T
K
Site 24
T272
K
K
E
D
R
P
P
T
Q
E
N
P
E
K
I
Site 25
S298
E
H
L
E
E
I
Q
S
K
R
Q
E
R
K
R
Site 26
S307
R
Q
E
R
K
R
R
S
T
A
N
P
A
Y
S
Site 27
T308
Q
E
R
K
R
R
S
T
A
N
P
A
Y
S
G
Site 28
Y313
R
S
T
A
N
P
A
Y
S
G
L
L
E
T
E
Site 29
T319
A
Y
S
G
L
L
E
T
E
R
K
R
L
A
S
Site 30
S326
T
E
R
K
R
L
A
S
N
Y
L
N
N
P
L
Site 31
Y328
R
K
R
L
A
S
N
Y
L
N
N
P
L
F
L
Site 32
T336
L
N
N
P
L
F
L
T
A
R
A
N
E
D
P
Site 33
T369
A
N
L
Q
P
C
G
T
C
P
G
A
Y
H
L
Site 34
S377
C
P
G
A
Y
H
L
S
C
L
E
P
P
L
K
Site 35
T424
H
S
Y
V
T
H
K
T
V
K
E
E
E
K
Q
Site 36
S438
Q
K
L
L
Q
R
G
S
E
L
Q
N
E
H
Q
Site 37
S456
E
R
D
R
R
L
A
S
A
V
Q
K
C
L
E
Site 38
S467
K
C
L
E
L
K
T
S
L
L
A
R
Q
R
G
Site 39
T475
L
L
A
R
Q
R
G
T
Q
S
S
L
D
R
L
Site 40
S478
R
Q
R
G
T
Q
S
S
L
D
R
L
R
A
L
Site 41
S516
A
G
P
W
T
K
P
S
V
A
A
T
H
P
T
Site 42
T520
T
K
P
S
V
A
A
T
H
P
T
V
Q
H
P
Site 43
T523
S
V
A
A
T
H
P
T
V
Q
H
P
Q
G
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation