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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RNF125
Full Name:
E3 ubiquitin-protein ligase RNF125
Alias:
RING finger protein 125;T-cell RING activation protein 1
Type:
Mass (Da):
26454
Number AA:
232
UniProt ID:
Q96EQ8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
G
S
V
L
S
T
D
S
G
K
S
A
Site 2
T7
_
M
G
S
V
L
S
T
D
S
G
K
S
A
P
Site 3
S9
G
S
V
L
S
T
D
S
G
K
S
A
P
A
S
Site 4
S12
L
S
T
D
S
G
K
S
A
P
A
S
A
T
A
Site 5
S16
S
G
K
S
A
P
A
S
A
T
A
R
A
L
E
Site 6
Y78
T
C
P
Y
C
R
A
Y
L
P
S
E
G
V
P
Site 7
S81
Y
C
R
A
Y
L
P
S
E
G
V
P
A
T
D
Site 8
T87
P
S
E
G
V
P
A
T
D
V
A
K
R
M
K
Site 9
S95
D
V
A
K
R
M
K
S
E
Y
K
N
C
A
E
Site 10
Y97
A
K
R
M
K
S
E
Y
K
N
C
A
E
C
D
Site 11
T118
E
M
R
A
H
I
R
T
C
Q
K
Y
I
D
K
Site 12
Y122
H
I
R
T
C
Q
K
Y
I
D
K
Y
G
P
L
Site 13
Y126
C
Q
K
Y
I
D
K
Y
G
P
L
Q
E
L
E
Site 14
T135
P
L
Q
E
L
E
E
T
A
A
R
C
V
C
P
Site 15
Y149
P
F
C
Q
R
E
L
Y
E
D
S
L
L
D
H
Site 16
S152
Q
R
E
L
Y
E
D
S
L
L
D
H
C
I
T
Site 17
T159
S
L
L
D
H
C
I
T
H
H
R
S
E
R
R
Site 18
S182
L
I
P
D
E
N
P
S
S
F
S
G
S
L
I
Site 19
S183
I
P
D
E
N
P
S
S
F
S
G
S
L
I
R
Site 20
S185
D
E
N
P
S
S
F
S
G
S
L
I
R
H
L
Site 21
S187
N
P
S
S
F
S
G
S
L
I
R
H
L
Q
V
Site 22
T197
R
H
L
Q
V
S
H
T
L
F
Y
D
D
F
I
Site 23
S221
I
R
R
V
L
D
R
S
L
L
E
Y
V
N
H
Site 24
Y225
L
D
R
S
L
L
E
Y
V
N
H
S
N
T
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation