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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RNFT2
Full Name:
RING finger and transmembrane domain-containing protein 2
Alias:
Type:
Mass (Da):
48965
Number AA:
444
UniProt ID:
Q96EX2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
R
K
M
Q
R
R
H
S
S
N
T
D
N
I
P
Site 2
S19
K
M
Q
R
R
H
S
S
N
T
D
N
I
P
P
Site 3
T21
Q
R
R
H
S
S
N
T
D
N
I
P
P
E
R
Site 4
S31
I
P
P
E
R
N
R
S
Q
A
L
S
S
E
A
Site 5
S35
R
N
R
S
Q
A
L
S
S
E
A
S
V
D
E
Site 6
S36
N
R
S
Q
A
L
S
S
E
A
S
V
D
E
G
Site 7
S39
Q
A
L
S
S
E
A
S
V
D
E
G
G
V
F
Site 8
S48
D
E
G
G
V
F
E
S
L
K
A
E
A
A
S
Site 9
S94
V
F
I
Q
M
P
A
S
R
E
E
G
G
G
R
Site 10
Y107
G
R
G
E
G
G
A
Y
H
H
R
Q
P
H
H
Site 11
S125
H
G
G
H
R
G
G
S
L
L
Q
H
V
G
G
Site 12
S138
G
G
D
H
R
G
H
S
E
E
G
G
D
E
Q
Site 13
T148
G
G
D
E
Q
P
G
T
P
A
P
A
L
S
E
Site 14
Y197
G
M
A
S
T
F
A
Y
A
N
S
T
L
R
E
Site 15
S200
S
T
F
A
Y
A
N
S
T
L
R
E
Q
V
S
Site 16
T201
T
F
A
Y
A
N
S
T
L
R
E
Q
V
S
L
Site 17
S207
S
T
L
R
E
Q
V
S
L
K
E
K
R
S
V
Site 18
Y233
G
N
T
L
Y
V
L
Y
T
F
S
S
Q
Q
L
Site 19
T234
N
T
L
Y
V
L
Y
T
F
S
S
Q
Q
L
Y
Site 20
S236
L
Y
V
L
Y
T
F
S
S
Q
Q
L
Y
N
S
Site 21
S237
Y
V
L
Y
T
F
S
S
Q
Q
L
Y
N
S
L
Site 22
Y241
T
F
S
S
Q
Q
L
Y
N
S
L
I
F
L
K
Site 23
S243
S
S
Q
Q
L
Y
N
S
L
I
F
L
K
P
N
Site 24
Y298
V
K
S
K
G
K
F
Y
L
V
I
E
E
L
S
Site 25
Y320
P
I
Q
L
W
Y
K
Y
I
M
G
D
D
S
S
Site 26
S326
K
Y
I
M
G
D
D
S
S
N
S
Y
F
L
G
Site 27
S327
Y
I
M
G
D
D
S
S
N
S
Y
F
L
G
G
Site 28
S329
M
G
D
D
S
S
N
S
Y
F
L
G
G
V
L
Site 29
T373
Q
N
Y
G
V
R
A
T
G
Q
Q
C
T
E
A
Site 30
T417
L
W
L
D
R
E
R
T
C
P
L
C
R
S
V
Site 31
T428
C
R
S
V
A
V
D
T
L
R
C
W
K
D
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation