KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
NRBF2
Full Name:
Nuclear receptor-binding factor 2
Alias:
Comodulator of PPAR and RXR; COPR1; COPR2; DKFZp564C1664; FLJ30395; NRBF-2; Nuclear receptor binding factor 2
Type:
Nuclear receptor co-regulator; Transcription, coactivator/corepressor
Mass (Da):
32378
Number AA:
287
UniProt ID:
Q96F24
International Prot ID:
IPI00550575
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
L
N
L
A
H
Q
Q
S
R
R
A
D
R
L
L
Site 2
Y27
R
L
L
A
A
G
K
Y
E
E
A
I
S
C
H
Site 3
S32
G
K
Y
E
E
A
I
S
C
H
K
K
A
A
A
Site 4
S42
K
K
A
A
A
Y
L
S
E
A
M
K
L
T
Q
Site 5
T48
L
S
E
A
M
K
L
T
Q
S
E
Q
A
H
L
Site 6
S50
E
A
M
K
L
T
Q
S
E
Q
A
H
L
S
L
Site 7
S56
Q
S
E
Q
A
H
L
S
L
E
L
Q
R
D
S
Site 8
S63
S
L
E
L
Q
R
D
S
H
M
K
Q
L
L
L
Site 9
T90
R
L
K
A
Q
Q
N
T
D
K
D
A
A
A
H
Site 10
T100
D
A
A
A
H
L
Q
T
S
H
K
P
S
A
E
Site 11
S101
A
A
A
H
L
Q
T
S
H
K
P
S
A
E
D
Site 12
S105
L
Q
T
S
H
K
P
S
A
E
D
A
E
G
Q
Site 13
S113
A
E
D
A
E
G
Q
S
P
L
S
Q
K
Y
S
Site 14
S116
A
E
G
Q
S
P
L
S
Q
K
Y
S
P
S
T
Site 15
S120
S
P
L
S
Q
K
Y
S
P
S
T
E
K
C
L
Site 16
S122
L
S
Q
K
Y
S
P
S
T
E
K
C
L
P
E
Site 17
T123
S
Q
K
Y
S
P
S
T
E
K
C
L
P
E
I
Site 18
T140
I
F
D
R
D
P
D
T
L
L
Y
L
L
Q
Q
Site 19
Y143
R
D
P
D
T
L
L
Y
L
L
Q
Q
K
S
G
Site 20
S149
L
Y
L
L
Q
Q
K
S
E
P
A
E
P
C
I
Site 21
T166
K
A
P
K
D
D
K
T
I
I
E
E
Q
A
T
Site 22
T173
T
I
I
E
E
Q
A
T
K
I
A
D
L
K
R
Site 23
S225
D
A
D
F
V
E
T
S
E
L
W
S
L
P
P
Site 24
S229
V
E
T
S
E
L
W
S
L
P
P
H
A
E
T
Site 25
T236
S
L
P
P
H
A
E
T
A
T
A
S
S
T
W
Site 26
S268
L
P
P
L
D
F
P
S
P
E
L
P
L
M
E
Site 27
S277
E
L
P
L
M
E
L
S
E
D
I
L
K
G
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation