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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LRRC46
Full Name:
Leucine-rich repeat-containing protein 46
Alias:
Type:
Uncharacterized
Mass (Da):
35430
Number AA:
321
UniProt ID:
Q96FV0
International Prot ID:
IPI00062265
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
S
G
G
K
S
A
Q
G
P
E
E
G
Site 2
T28
L
I
T
K
R
N
L
T
F
P
E
D
G
E
L
Site 3
T48
H
T
L
D
E
L
Q
T
V
R
L
D
R
E
G
Site 4
T58
L
D
R
E
G
I
T
T
I
R
N
L
E
G
L
Site 5
S70
E
G
L
Q
N
L
H
S
L
Y
L
Q
G
N
K
Site 6
Y72
L
Q
N
L
H
S
L
Y
L
Q
G
N
K
I
Q
Site 7
Y150
S
C
T
N
Q
D
G
Y
R
E
L
V
T
E
A
Site 8
S175
P
V
V
E
R
W
I
S
D
E
E
D
E
A
S
Site 9
S182
S
D
E
E
D
E
A
S
S
D
E
E
F
P
E
Site 10
S183
D
E
E
D
E
A
S
S
D
E
E
F
P
E
L
Site 11
S191
D
E
E
F
P
E
L
S
G
P
F
C
S
E
R
Site 12
S196
E
L
S
G
P
F
C
S
E
R
G
F
L
K
E
Site 13
S209
K
E
L
E
Q
E
L
S
R
H
R
E
H
R
Q
Site 14
T218
H
R
E
H
R
Q
Q
T
A
L
T
E
H
L
L
Site 15
S248
G
V
P
M
A
G
D
S
S
P
S
A
T
P
A
Site 16
S249
V
P
M
A
G
D
S
S
P
S
A
T
P
A
Q
Site 17
S251
M
A
G
D
S
S
P
S
A
T
P
A
Q
G
E
Site 18
T253
G
D
S
S
P
S
A
T
P
A
Q
G
E
E
T
Site 19
S266
E
T
V
P
E
A
V
S
S
P
Q
A
S
S
P
Site 20
S267
T
V
P
E
A
V
S
S
P
Q
A
S
S
P
T
Site 21
S271
A
V
S
S
P
Q
A
S
S
P
T
K
K
P
C
Site 22
S272
V
S
S
P
Q
A
S
S
P
T
K
K
P
C
S
Site 23
S279
S
P
T
K
K
P
C
S
L
I
P
R
G
H
Q
Site 24
S287
L
I
P
R
G
H
Q
S
S
F
W
G
R
K
G
Site 25
S288
I
P
R
G
H
Q
S
S
F
W
G
R
K
G
A
Site 26
T299
R
K
G
A
R
A
A
T
A
P
K
A
S
V
A
Site 27
S304
A
A
T
A
P
K
A
S
V
A
E
A
P
S
T
Site 28
S310
A
S
V
A
E
A
P
S
T
T
K
T
T
A
K
Site 29
T311
S
V
A
E
A
P
S
T
T
K
T
T
A
K
R
Site 30
T314
E
A
P
S
T
T
K
T
T
A
K
R
S
K
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation