PhosphoNET

           
Protein Info 
   
Short Name:  PERP
Full Name:  p53 apoptosis effector related to PMP-22
Alias:  Keratinocytes-associated protein 1
Type: 
Mass (Da):  21368
Number AA:  193
UniProt ID:  Q96FX8
International Prot ID:  IPI00293189
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005886  GO:0016020  GO:0016021 Uniprot OncoNet
Molecular Function:  GO:0005198  GO:0005488  GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0006915  GO:0007155  GO:0008219 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S38AGRGWLQSSDHGQTS
Site 2S39GRGWLQSSDHGQTSS
Site 3S46SDHGQTSSLWWKCSQ
Site 4S52SSLWWKCSQEGGGSG
Site 5S58CSQEGGGSGSYEEGC
Site 6S60QEGGGSGSYEEGCQS
Site 7Y61EGGGSGSYEEGCQSL
Site 8Y71GCQSLMEYAWGRAAA
Site 9T136YPVKYTQTFTLHANP
Site 10T138VKYTQTFTLHANPAV
Site 11Y149NPAVTYIYNWAYGFG
Site 12Y188LGNAKPRYFYTSA__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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