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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BICD1
Full Name:
Protein bicaudal D homolog 1
Alias:
Cytoskeleton-like bicaudal D 1
Type:
Cytoskeleton, Golgi apparatus protein
Mass (Da):
110750
Number AA:
975
UniProt ID:
Q96G01
International Prot ID:
IPI00018368
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005856
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005200
PhosphoSite+
KinaseNET
Biological Process:
GO:0006396
GO:0009653
GO:0008298
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
A
A
E
E
V
L
Q
T
V
D
H
Y
K
T
E
Site 2
Y13
V
L
Q
T
V
D
H
Y
K
T
E
I
E
R
L
Site 3
T21
K
T
E
I
E
R
L
T
K
E
L
T
E
T
T
Site 4
T27
L
T
K
E
L
T
E
T
T
H
E
K
I
Q
A
Site 5
T47
V
V
L
E
E
K
L
T
L
K
Q
Q
Y
D
E
Site 6
Y52
K
L
T
L
K
Q
Q
Y
D
E
L
E
A
E
Y
Site 7
S61
E
L
E
A
E
Y
D
S
L
K
Q
E
L
E
Q
Site 8
S76
L
K
E
A
F
G
Q
S
F
S
I
H
R
K
V
Site 9
S78
E
A
F
G
Q
S
F
S
I
H
R
K
V
A
E
Site 10
T89
K
V
A
E
D
G
E
T
R
E
E
T
L
L
Q
Site 11
T93
D
G
E
T
R
E
E
T
L
L
Q
E
S
A
S
Site 12
S98
E
E
T
L
L
Q
E
S
A
S
K
E
A
Y
Y
Site 13
S100
T
L
L
Q
E
S
A
S
K
E
A
Y
Y
L
G
Site 14
Y104
E
S
A
S
K
E
A
Y
Y
L
G
K
I
L
E
Site 15
Y105
S
A
S
K
E
A
Y
Y
L
G
K
I
L
E
M
Site 16
S119
M
Q
N
E
L
K
Q
S
R
A
V
V
T
N
V
Site 17
T134
Q
A
E
N
E
R
L
T
A
V
V
Q
D
L
K
Site 18
Y161
M
K
D
E
I
R
E
Y
K
F
R
E
A
R
L
Site 19
Y172
E
A
R
L
L
Q
D
Y
T
E
L
E
E
E
N
Site 20
T173
A
R
L
L
Q
D
Y
T
E
L
E
E
E
N
I
Site 21
T181
E
L
E
E
E
N
I
T
L
Q
K
L
V
S
T
Site 22
S187
I
T
L
Q
K
L
V
S
T
L
K
Q
N
Q
V
Site 23
T210
I
K
R
F
E
E
E
T
V
L
L
N
S
Q
L
Site 24
S215
E
E
T
V
L
L
N
S
Q
L
E
D
A
I
R
Site 25
T237
Q
L
E
E
A
L
E
T
L
K
N
E
R
E
Q
Site 26
S253
N
N
L
R
K
E
L
S
Q
Y
I
S
L
N
D
Site 27
Y255
L
R
K
E
L
S
Q
Y
I
S
L
N
D
N
H
Site 28
S257
K
E
L
S
Q
Y
I
S
L
N
D
N
H
I
S
Site 29
S266
N
D
N
H
I
S
I
S
V
D
G
L
K
F
A
Site 30
S277
L
K
F
A
E
D
G
S
E
P
N
N
D
D
K
Site 31
Y300
L
V
K
L
N
G
D
Y
R
T
P
T
L
R
K
Site 32
T302
K
L
N
G
D
Y
R
T
P
T
L
R
K
G
E
Site 33
T304
N
G
D
Y
R
T
P
T
L
R
K
G
E
S
L
Site 34
S310
P
T
L
R
K
G
E
S
L
N
P
V
S
D
L
Site 35
S315
G
E
S
L
N
P
V
S
D
L
F
S
E
L
N
Site 36
S319
N
P
V
S
D
L
F
S
E
L
N
I
S
E
I
Site 37
S324
L
F
S
E
L
N
I
S
E
I
Q
K
L
K
Q
Site 38
S350
L
L
A
N
L
Q
E
S
Q
T
Q
L
E
H
T
Site 39
T372
H
E
R
V
H
R
L
T
E
H
V
N
A
M
R
Site 40
S384
A
M
R
G
L
Q
S
S
K
E
L
K
A
E
L
Site 41
S399
D
G
E
K
G
R
D
S
G
E
E
A
H
D
Y
Site 42
Y406
S
G
E
E
A
H
D
Y
E
V
D
I
N
G
L
Site 43
Y441
I
K
A
L
K
E
K
Y
N
K
S
V
E
N
Y
Site 44
S444
L
K
E
K
Y
N
K
S
V
E
N
Y
T
D
E
Site 45
Y448
Y
N
K
S
V
E
N
Y
T
D
E
K
A
K
Y
Site 46
Y455
Y
T
D
E
K
A
K
Y
E
S
K
I
Q
M
Y
Site 47
Y462
Y
E
S
K
I
Q
M
Y
D
E
Q
V
T
S
L
Site 48
S468
M
Y
D
E
Q
V
T
S
L
E
K
T
T
K
E
Site 49
T472
Q
V
T
S
L
E
K
T
T
K
E
S
G
E
K
Site 50
S492
K
E
L
Q
K
M
T
S
I
A
N
E
N
H
S
Site 51
S499
S
I
A
N
E
N
H
S
T
L
N
T
A
Q
D
Site 52
T500
I
A
N
E
N
H
S
T
L
N
T
A
Q
D
E
Site 53
T503
E
N
H
S
T
L
N
T
A
Q
D
E
L
V
T
Site 54
T510
T
A
Q
D
E
L
V
T
F
S
E
E
L
A
Q
Site 55
S512
Q
D
E
L
V
T
F
S
E
E
L
A
Q
L
Y
Site 56
Y519
S
E
E
L
A
Q
L
Y
H
H
V
C
L
C
N
Site 57
Y537
P
N
R
V
M
L
D
Y
Y
R
Q
S
R
V
T
Site 58
Y538
N
R
V
M
L
D
Y
Y
R
Q
S
R
V
T
R
Site 59
S541
M
L
D
Y
Y
R
Q
S
R
V
T
R
S
G
S
Site 60
T544
Y
Y
R
Q
S
R
V
T
R
S
G
S
L
K
G
Site 61
S546
R
Q
S
R
V
T
R
S
G
S
L
K
G
P
D
Site 62
S548
S
R
V
T
R
S
G
S
L
K
G
P
D
D
P
Site 63
S560
D
D
P
R
G
L
L
S
P
R
L
A
R
R
G
Site 64
S569
R
L
A
R
R
G
V
S
S
P
V
E
T
R
T
Site 65
S570
L
A
R
R
G
V
S
S
P
V
E
T
R
T
S
Site 66
T574
G
V
S
S
P
V
E
T
R
T
S
S
E
P
V
Site 67
T576
S
S
P
V
E
T
R
T
S
S
E
P
V
A
K
Site 68
S577
S
P
V
E
T
R
T
S
S
E
P
V
A
K
E
Site 69
S578
P
V
E
T
R
T
S
S
E
P
V
A
K
E
S
Site 70
S585
S
E
P
V
A
K
E
S
T
E
A
S
K
E
P
Site 71
S589
A
K
E
S
T
E
A
S
K
E
P
S
P
T
K
Site 72
S593
T
E
A
S
K
E
P
S
P
T
K
T
P
T
I
Site 73
T595
A
S
K
E
P
S
P
T
K
T
P
T
I
S
P
Site 74
T597
K
E
P
S
P
T
K
T
P
T
I
S
P
V
I
Site 75
T599
P
S
P
T
K
T
P
T
I
S
P
V
I
T
A
Site 76
S601
P
T
K
T
P
T
I
S
P
V
I
T
A
P
P
Site 77
T605
P
T
I
S
P
V
I
T
A
P
P
S
S
P
V
Site 78
S610
V
I
T
A
P
P
S
S
P
V
L
D
T
S
D
Site 79
S616
S
S
P
V
L
D
T
S
D
I
R
K
E
P
M
Site 80
Y626
R
K
E
P
M
N
I
Y
N
L
N
A
I
I
R
Site 81
S646
L
Q
K
A
V
D
R
S
L
Q
L
S
R
Q
R
Site 82
S650
V
D
R
S
L
Q
L
S
R
Q
R
A
A
A
R
Site 83
S679
E
E
I
L
K
L
K
S
L
L
S
T
K
R
E
Site 84
S682
L
K
L
K
S
L
L
S
T
K
R
E
Q
I
A
Site 85
T683
K
L
K
S
L
L
S
T
K
R
E
Q
I
A
T
Site 86
T690
T
K
R
E
Q
I
A
T
L
R
A
V
L
K
A
Site 87
T701
V
L
K
A
N
K
Q
T
A
E
V
A
L
A
N
Site 88
Y713
L
A
N
L
K
N
K
Y
E
N
E
K
A
M
V
Site 89
T740
A
L
K
E
D
A
A
T
F
S
S
L
R
A
M
Site 90
T750
S
L
R
A
M
F
A
T
R
C
D
E
Y
V
T
Site 91
Y755
F
A
T
R
C
D
E
Y
V
T
Q
L
D
E
M
Site 92
T775
A
A
E
D
E
K
K
T
L
N
T
L
L
R
M
Site 93
S804
L
E
F
D
H
E
Q
S
R
R
S
K
G
K
L
Site 94
S807
D
H
E
Q
S
R
R
S
K
G
K
L
G
K
S
Site 95
S814
S
K
G
K
L
G
K
S
K
I
G
S
P
K
V
Site 96
S818
L
G
K
S
K
I
G
S
P
K
V
S
G
E
A
Site 97
S822
K
I
G
S
P
K
V
S
G
E
A
S
V
T
V
Site 98
S826
P
K
V
S
G
E
A
S
V
T
V
P
T
I
D
Site 99
Y835
T
V
P
T
I
D
T
Y
L
L
H
S
Q
G
P
Site 100
S839
I
D
T
Y
L
L
H
S
Q
G
P
Q
T
P
N
Site 101
T844
L
H
S
Q
G
P
Q
T
P
N
I
R
V
S
S
Site 102
S850
Q
T
P
N
I
R
V
S
S
G
T
Q
R
K
R
Site 103
S851
T
P
N
I
R
V
S
S
G
T
Q
R
K
R
Q
Site 104
T853
N
I
R
V
S
S
G
T
Q
R
K
R
Q
F
S
Site 105
S860
T
Q
R
K
R
Q
F
S
P
S
L
C
D
Q
S
Site 106
S862
R
K
R
Q
F
S
P
S
L
C
D
Q
S
R
P
Site 107
S867
S
P
S
L
C
D
Q
S
R
P
R
T
S
G
A
Site 108
T871
C
D
Q
S
R
P
R
T
S
G
A
S
Y
L
Q
Site 109
S872
D
Q
S
R
P
R
T
S
G
A
S
Y
L
Q
N
Site 110
S875
R
P
R
T
S
G
A
S
Y
L
Q
N
L
L
R
Site 111
Y876
P
R
T
S
G
A
S
Y
L
Q
N
L
L
R
V
Site 112
T888
L
R
V
P
P
D
P
T
S
T
E
S
F
L
L
Site 113
S889
R
V
P
P
D
P
T
S
T
E
S
F
L
L
K
Site 114
T890
V
P
P
D
P
T
S
T
E
S
F
L
L
K
G
Site 115
S892
P
D
P
T
S
T
E
S
F
L
L
K
G
P
P
Site 116
S902
L
K
G
P
P
S
M
S
E
F
I
Q
G
H
R
Site 117
S911
F
I
Q
G
H
R
L
S
K
E
K
R
L
T
V
Site 118
T917
L
S
K
E
K
R
L
T
V
A
P
P
D
C
Q
Site 119
S929
D
C
Q
Q
P
A
A
S
V
P
P
Q
C
S
Q
Site 120
S935
A
S
V
P
P
Q
C
S
Q
L
A
G
R
Q
D
Site 121
T945
A
G
R
Q
D
C
P
T
V
S
P
D
T
A
L
Site 122
S947
R
Q
D
C
P
T
V
S
P
D
T
A
L
P
E
Site 123
T950
C
P
T
V
S
P
D
T
A
L
P
E
E
Q
P
Site 124
S959
L
P
E
E
Q
P
H
S
S
S
Q
C
A
P
L
Site 125
S961
E
E
Q
P
H
S
S
S
Q
C
A
P
L
H
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation