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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DUS3L
Full Name:
tRNA-dihydrouridine synthase 3-like
Alias:
dihydrouridine synthase 3-like; DUS3; FLJ13896
Type:
EC 1.-.-.-; Oxidoreductase
Mass (Da):
72594
Number AA:
650
UniProt ID:
Q96G46
International Prot ID:
IPI00784107
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0050660
GO:0003676
GO:0017150
PhosphoSite+
KinaseNET
Biological Process:
GO:0055114
GO:0008033
GO:0006399
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
E
N
G
G
G
G
D
S
G
A
G
A
L
E
R
Site 2
Y34
V
A
P
I
K
R
Q
Y
L
T
T
K
E
Q
F
Site 3
T37
I
K
R
Q
Y
L
T
T
K
E
Q
F
H
Q
F
Site 4
T53
E
A
K
G
Q
E
K
T
C
R
E
T
E
V
G
Site 5
T57
Q
E
K
T
C
R
E
T
E
V
G
D
P
A
G
Site 6
T82
I
R
L
E
D
G
Q
T
A
D
G
Q
T
E
E
Site 7
T99
E
P
G
E
Q
L
Q
T
Q
K
R
A
R
G
Q
Site 8
Y118
P
H
V
K
P
T
N
Y
D
K
N
R
L
C
P
Site 9
S126
D
K
N
R
L
C
P
S
L
I
Q
E
S
A
A
Site 10
Y150
F
L
H
D
V
G
R
Y
L
E
T
K
P
A
D
Site 11
Y173
E
T
F
G
R
C
P
Y
G
V
T
C
R
F
A
Site 12
T201
E
E
L
A
A
R
G
T
Q
P
P
S
I
R
N
Site 13
S205
A
R
G
T
Q
P
P
S
I
R
N
G
L
D
K
Site 14
S236
E
Q
A
L
R
R
F
S
Q
G
P
T
P
A
A
Site 15
T240
R
R
F
S
Q
G
P
T
P
A
A
A
V
P
E
Site 16
T271
Q
V
P
A
G
P
G
T
S
T
P
P
S
S
P
Site 17
S272
V
P
A
G
P
G
T
S
T
P
P
S
S
P
V
Site 18
T273
P
A
G
P
G
T
S
T
P
P
S
S
P
V
R
Site 19
S276
P
G
T
S
T
P
P
S
S
P
V
R
T
C
G
Site 20
S277
G
T
S
T
P
P
S
S
P
V
R
T
C
G
P
Site 21
T281
P
P
S
S
P
V
R
T
C
G
P
L
T
D
E
Site 22
T286
V
R
T
C
G
P
L
T
D
E
D
V
V
R
L
Site 23
Y308
L
D
I
R
G
K
L
Y
L
A
P
L
T
T
C
Site 24
S348
N
L
L
Q
G
Q
M
S
E
W
A
L
L
K
R
Site 25
T463
D
W
G
V
A
L
V
T
L
H
G
R
S
R
E
Site 26
T474
R
S
R
E
Q
R
Y
T
K
L
A
D
W
Q
Y
Site 27
Y481
T
K
L
A
D
W
Q
Y
I
E
E
C
V
Q
A
Site 28
S490
E
E
C
V
Q
A
A
S
P
M
P
L
F
G
N
Site 29
S502
F
G
N
G
D
I
L
S
F
E
D
A
N
R
A
Site 30
S542
E
Q
R
H
W
D
I
S
S
S
E
R
L
D
I
Site 31
S543
Q
R
H
W
D
I
S
S
S
E
R
L
D
I
L
Site 32
S544
R
H
W
D
I
S
S
S
E
R
L
D
I
L
R
Site 33
Y556
I
L
R
D
F
T
N
Y
G
L
E
H
W
G
S
Site 34
S563
Y
G
L
E
H
W
G
S
D
T
Q
G
V
E
K
Site 35
T565
L
E
H
W
G
S
D
T
Q
G
V
E
K
T
R
Site 36
T571
D
T
Q
G
V
E
K
T
R
R
F
L
L
E
W
Site 37
S580
R
F
L
L
E
W
L
S
F
L
C
R
Y
V
P
Site 38
Y604
R
I
N
E
R
P
P
Y
Y
L
G
R
D
Y
L
Site 39
Y605
I
N
E
R
P
P
Y
Y
L
G
R
D
Y
L
E
Site 40
Y610
P
Y
Y
L
G
R
D
Y
L
E
T
L
M
A
S
Site 41
T613
L
G
R
D
Y
L
E
T
L
M
A
S
Q
K
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation