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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
OTUD5
Full Name:
OTU domain-containing protein 5
Alias:
Deubiquinating enzyme A; DKFZp761A052; DUBA; Hypothetical protein DKFZp761A052; OTU domain containing 5
Type:
EC 3.1.2.15; Protease
Mass (Da):
60626
Number AA:
571
UniProt ID:
Q96G74
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0008234
GO:0004221
GO:0004843
PhosphoSite+
KinaseNET
Biological Process:
GO:0019941
GO:0006511
GO:0008152
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S54
G
G
D
R
D
R
D
S
G
V
V
G
A
R
P
Site 2
S64
V
G
A
R
P
R
A
S
P
P
P
Q
G
P
L
Site 3
S99
G
P
R
P
Q
Q
A
S
P
P
P
C
G
G
P
Site 4
S144
V
G
V
G
G
C
C
S
G
P
G
H
S
K
R
Site 5
S149
C
C
S
G
P
G
H
S
K
R
R
R
Q
A
P
Site 6
S165
V
G
A
V
G
G
G
S
P
E
R
E
E
V
G
Site 7
Y175
R
E
E
V
G
A
G
Y
N
S
E
D
E
Y
E
Site 8
S177
E
V
G
A
G
Y
N
S
E
D
E
Y
E
A
A
Site 9
Y181
G
Y
N
S
E
D
E
Y
E
A
A
A
A
R
I
Site 10
T195
I
E
A
M
D
P
A
T
V
E
Q
Q
E
H
W
Site 11
Y234
R
A
V
A
D
Q
V
Y
G
D
Q
D
M
H
E
Site 12
Y250
V
R
K
H
C
M
D
Y
L
M
K
N
A
D
Y
Site 13
Y257
Y
L
M
K
N
A
D
Y
F
S
N
Y
V
T
E
Site 14
Y261
N
A
D
Y
F
S
N
Y
V
T
E
D
F
T
T
Site 15
T268
Y
V
T
E
D
F
T
T
Y
I
N
R
K
R
K
Site 16
Y269
V
T
E
D
F
T
T
Y
I
N
R
K
R
K
N
Site 17
Y292
M
Q
A
M
A
E
M
Y
N
R
P
V
E
V
Y
Site 18
Y299
Y
N
R
P
V
E
V
Y
Q
Y
S
T
G
T
S
Site 19
Y301
R
P
V
E
V
Y
Q
Y
S
T
G
T
S
A
V
Site 20
S302
P
V
E
V
Y
Q
Y
S
T
G
T
S
A
V
E
Site 21
S306
Y
Q
Y
S
T
G
T
S
A
V
E
P
I
N
T
Site 22
T313
S
A
V
E
P
I
N
T
F
H
G
I
H
Q
N
Site 23
Y329
D
E
P
I
R
V
S
Y
H
R
N
I
H
Y
N
Site 24
Y335
S
Y
H
R
N
I
H
Y
N
S
V
V
N
P
N
Site 25
S363
K
P
G
F
A
E
Q
S
L
M
K
N
A
I
K
Site 26
T371
L
M
K
N
A
I
K
T
S
E
E
S
W
I
E
Site 27
T389
L
E
D
K
K
R
A
T
D
W
E
A
T
N
E
Site 28
S406
E
E
Q
V
A
R
E
S
Y
L
Q
W
L
R
D
Site 29
Y407
E
Q
V
A
R
E
S
Y
L
Q
W
L
R
D
Q
Site 30
S425
A
R
Q
V
R
G
P
S
Q
P
R
K
A
S
A
Site 31
S431
P
S
Q
P
R
K
A
S
A
T
C
S
S
A
T
Site 32
T433
Q
P
R
K
A
S
A
T
C
S
S
A
T
A
A
Site 33
S435
R
K
A
S
A
T
C
S
S
A
T
A
A
A
S
Site 34
T449
S
S
G
L
E
E
W
T
S
R
S
P
R
Q
R
Site 35
S450
S
G
L
E
E
W
T
S
R
S
P
R
Q
R
S
Site 36
S452
L
E
E
W
T
S
R
S
P
R
Q
R
S
S
A
Site 37
S457
S
R
S
P
R
Q
R
S
S
A
S
S
P
E
H
Site 38
S458
R
S
P
R
Q
R
S
S
A
S
S
P
E
H
P
Site 39
S460
P
R
Q
R
S
S
A
S
S
P
E
H
P
E
L
Site 40
S461
R
Q
R
S
S
A
S
S
P
E
H
P
E
L
H
Site 41
T480
M
K
P
P
S
P
G
T
V
L
A
L
A
K
P
Site 42
T495
P
S
P
C
A
P
G
T
S
S
Q
F
S
A
G
Site 43
S497
P
C
A
P
G
T
S
S
Q
F
S
A
G
A
D
Site 44
S500
P
G
T
S
S
Q
F
S
A
G
A
D
R
A
T
Site 45
T507
S
A
G
A
D
R
A
T
S
P
L
V
S
L
Y
Site 46
S508
A
G
A
D
R
A
T
S
P
L
V
S
L
Y
P
Site 47
S512
R
A
T
S
P
L
V
S
L
Y
P
A
L
E
C
Site 48
S527
R
A
L
I
Q
Q
M
S
P
S
A
F
G
L
N
Site 49
S529
L
I
Q
Q
M
S
P
S
A
F
G
L
N
D
W
Site 50
S544
D
D
D
E
I
L
A
S
V
L
A
V
S
Q
Q
Site 51
Y553
L
A
V
S
Q
Q
E
Y
L
D
S
M
K
K
N
Site 52
S556
S
Q
Q
E
Y
L
D
S
M
K
K
N
K
V
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation