PhosphoNET

           
Protein Info 
   
Short Name:  BSCL2
Full Name:  Seipin
Alias:  Bernardinelli-Seip congenital lipodystrophy type 2 protein
Type: 
Mass (Da):  44392
Number AA:  398
UniProt ID:  Q96G97
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y56YGSFYYSYMPTVSHL
Site 2S64MPTVSHLSPVHFYYR
Site 3Y69HLSPVHFYYRTDCDS
Site 4Y70LSPVHFYYRTDCDSS
Site 5T72PVHFYYRTDCDSSTT
Site 6S76YYRTDCDSSTTSLCS
Site 7S77YRTDCDSSTTSLCSF
Site 8T78RTDCDSSTTSLCSFP
Site 9S90SFPVANVSLTKGGRD
Site 10Y102GRDRVLMYGQPYRVT
Site 11Y106VLMYGQPYRVTLELE
Site 12T109YGQPYRVTLELELPE
Site 13S117LELELPESPVNQDLG
Site 14S141TRGGRIISTSSRSVM
Site 15T142RGGRIISTSSRSVML
Site 16S143GGRIISTSSRSVMLH
Site 17S144GRIISTSSRSVMLHY
Site 18Y151SRSVMLHYRSDLLQM
Site 19Y184QLLEVELYADYRENS
Site 20Y187EVELYADYRENSYVP
Site 21S191YADYRENSYVPTTGA
Site 22Y192ADYRENSYVPTTGAI
Site 23T195RENSYVPTTGAIIEI
Site 24Y210HSKRIQLYGAYLRIH
Site 25S280NIRKRDNSRKEVQRR
Site 26S289KEVQRRISAHQPGAG
Site 27S351EPEASDGSGSWEDAA
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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