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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF274
Full Name:
Zinc finger protein 274
Alias:
Zinc finger protein HFB101;Zinc finger protein with KRAB and SCAN domains 19;Zinc finger protein zfp2
Type:
Mass (Da):
74191
Number AA:
653
UniProt ID:
Q96GC6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
A
S
R
L
P
T
A
W
S
C
E
P
V
Site 2
S10
S
R
L
P
T
A
W
S
C
E
P
V
T
F
E
Site 3
T20
P
V
T
F
E
D
V
T
L
G
F
T
P
E
E
Site 4
T24
E
D
V
T
L
G
F
T
P
E
E
W
G
L
L
Site 5
S37
L
L
D
L
K
Q
K
S
L
Y
R
E
V
M
L
Site 6
Y39
D
L
K
Q
K
S
L
Y
R
E
V
M
L
E
N
Site 7
S52
E
N
Y
R
N
L
V
S
V
E
H
Q
L
S
K
Site 8
S58
V
S
V
E
H
Q
L
S
K
P
D
V
V
S
Q
Site 9
S64
L
S
K
P
D
V
V
S
Q
L
E
E
A
E
D
Site 10
T83
E
R
G
I
P
Q
D
T
I
P
E
Y
P
E
L
Site 11
Y87
P
Q
D
T
I
P
E
Y
P
E
L
Q
L
D
P
Site 12
Y132
N
A
Q
I
Q
A
L
Y
A
E
D
G
S
L
S
Site 13
S137
A
L
Y
A
E
D
G
S
L
S
A
D
A
P
S
Site 14
S139
Y
A
E
D
G
S
L
S
A
D
A
P
S
E
Q
Site 15
Y169
Q
R
F
R
Q
F
R
Y
K
D
M
T
G
P
R
Site 16
T173
Q
F
R
Y
K
D
M
T
G
P
R
E
A
L
D
Site 17
T219
A
L
P
V
K
L
R
T
W
V
E
S
Q
H
P
Site 18
S297
Q
D
V
A
V
D
F
S
R
E
E
W
G
L
L
Site 19
T307
E
W
G
L
L
G
P
T
Q
R
T
E
Y
R
D
Site 20
Y312
G
P
T
Q
R
T
E
Y
R
D
V
M
L
E
T
Site 21
S341
N
K
E
L
A
P
N
S
D
I
P
E
E
E
P
Site 22
S351
P
E
E
E
P
A
P
S
L
K
V
Q
E
S
S
Site 23
S357
P
S
L
K
V
Q
E
S
S
R
D
C
A
L
S
Site 24
S364
S
S
R
D
C
A
L
S
S
T
L
E
D
T
L
Site 25
S365
S
R
D
C
A
L
S
S
T
L
E
D
T
L
Q
Site 26
T366
R
D
C
A
L
S
S
T
L
E
D
T
L
Q
G
Site 27
T370
L
S
S
T
L
E
D
T
L
Q
G
G
V
Q
E
Site 28
T381
G
V
Q
E
V
Q
D
T
V
L
K
Q
M
E
S
Site 29
S388
T
V
L
K
Q
M
E
S
A
Q
E
K
D
L
P
Site 30
S405
K
H
F
D
N
R
E
S
Q
A
N
S
G
A
L
Site 31
S409
N
R
E
S
Q
A
N
S
G
A
L
D
T
N
Q
Site 32
T414
A
N
S
G
A
L
D
T
N
Q
V
S
L
Q
K
Site 33
S418
A
L
D
T
N
Q
V
S
L
Q
K
I
D
N
P
Site 34
S427
Q
K
I
D
N
P
E
S
Q
A
N
S
G
A
L
Site 35
S431
N
P
E
S
Q
A
N
S
G
A
L
D
T
N
Q
Site 36
T436
A
N
S
G
A
L
D
T
N
Q
V
L
L
H
K
Site 37
S455
K
R
L
R
K
R
D
S
Q
V
K
S
M
K
H
Site 38
S459
K
R
D
S
Q
V
K
S
M
K
H
N
S
R
V
Site 39
S464
V
K
S
M
K
H
N
S
R
V
K
I
H
Q
K
Site 40
S472
R
V
K
I
H
Q
K
S
C
E
R
Q
K
A
K
Site 41
T487
E
G
N
G
C
R
K
T
F
S
R
S
T
K
Q
Site 42
S489
N
G
C
R
K
T
F
S
R
S
T
K
Q
I
T
Site 43
S491
C
R
K
T
F
S
R
S
T
K
Q
I
T
F
I
Site 44
T492
R
K
T
F
S
R
S
T
K
Q
I
T
F
I
R
Site 45
T496
S
R
S
T
K
Q
I
T
F
I
R
I
H
K
G
Site 46
Y521
K
I
F
R
N
P
R
Y
F
S
V
H
K
K
I
Site 47
Y535
I
H
T
G
E
R
P
Y
V
C
Q
D
C
G
K
Site 48
S547
C
G
K
G
F
V
Q
S
S
S
L
T
Q
H
Q
Site 49
S548
G
K
G
F
V
Q
S
S
S
L
T
Q
H
Q
R
Site 50
S549
K
G
F
V
Q
S
S
S
L
T
Q
H
Q
R
V
Site 51
T551
F
V
Q
S
S
S
L
T
Q
H
Q
R
V
H
S
Site 52
S558
T
Q
H
Q
R
V
H
S
G
E
R
P
F
E
C
Site 53
T571
E
C
Q
E
C
G
R
T
F
N
D
R
S
A
I
Site 54
S576
G
R
T
F
N
D
R
S
A
I
S
Q
H
L
R
Site 55
S579
F
N
D
R
S
A
I
S
Q
H
L
R
T
H
T
Site 56
T586
S
Q
H
L
R
T
H
T
G
A
K
P
Y
K
C
Site 57
S603
C
G
K
A
F
R
Q
S
S
H
L
I
R
H
Q
Site 58
S604
G
K
A
F
R
Q
S
S
H
L
I
R
H
Q
R
Site 59
T614
I
R
H
Q
R
T
H
T
G
E
R
P
Y
A
C
Site 60
Y619
T
H
T
G
E
R
P
Y
A
C
N
K
C
G
K
Site 61
T629
N
K
C
G
K
A
F
T
Q
S
S
H
L
I
G
Site 62
S632
G
K
A
F
T
Q
S
S
H
L
I
G
H
Q
R
Site 63
T644
H
Q
R
T
H
N
R
T
K
R
K
K
K
Q
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation