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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRMT2B
Full Name:
tRNA (uracil-5-)-methyltransferase homolog
Alias:
TRM2 homolog
Type:
Mass (Da):
56476
Number AA:
504
UniProt ID:
Q96GJ1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
K
R
R
V
P
L
H
S
L
R
Y
F
I
S
M
Site 2
Y32
K
P
G
L
L
P
W
Y
A
R
N
P
P
G
W
Site 3
S40
A
R
N
P
P
G
W
S
Q
L
F
L
G
T
V
Site 4
S66
K
C
Q
K
G
Q
K
S
Q
K
K
P
S
H
L
Site 5
S79
H
L
G
P
L
D
G
S
W
Q
E
R
L
A
D
Site 6
T89
E
R
L
A
D
V
V
T
P
L
W
R
L
S
Y
Site 7
S95
V
T
P
L
W
R
L
S
Y
E
E
Q
L
K
V
Site 8
Y96
T
P
L
W
R
L
S
Y
E
E
Q
L
K
V
K
Site 9
S116
K
I
L
Q
R
L
E
S
Y
I
Q
M
L
N
G
Site 10
T128
L
N
G
V
S
V
T
T
A
V
P
K
S
E
R
Site 11
Y152
P
S
P
V
I
N
G
Y
R
N
K
S
T
F
S
Site 12
S156
I
N
G
Y
R
N
K
S
T
F
S
V
N
R
G
Site 13
T157
N
G
Y
R
N
K
S
T
F
S
V
N
R
G
P
Site 14
S159
Y
R
N
K
S
T
F
S
V
N
R
G
P
D
G
Site 15
T170
G
P
D
G
N
P
K
T
V
G
F
Y
L
G
T
Site 16
S199
K
N
I
P
E
K
H
S
Q
V
A
Q
Y
Y
E
Site 17
Y204
K
H
S
Q
V
A
Q
Y
Y
E
V
F
L
R
Q
Site 18
Y225
L
V
F
H
E
G
G
Y
W
R
E
L
T
V
R
Site 19
T230
G
G
Y
W
R
E
L
T
V
R
T
N
S
Q
G
Site 20
T233
W
R
E
L
T
V
R
T
N
S
Q
G
H
T
M
Site 21
S235
E
L
T
V
R
T
N
S
Q
G
H
T
M
A
I
Site 22
T239
R
T
N
S
Q
G
H
T
M
A
I
I
T
F
H
Site 23
T244
G
H
T
M
A
I
I
T
F
H
P
Q
K
L
S
Site 24
S251
T
F
H
P
Q
K
L
S
Q
E
E
L
H
V
Q
Site 25
T285
S
L
Y
F
Q
E
S
T
M
T
R
C
S
H
Q
Site 26
S290
E
S
T
M
T
R
C
S
H
Q
Q
S
P
Y
Q
Site 27
S294
T
R
C
S
H
Q
Q
S
P
Y
Q
L
L
F
G
Site 28
Y296
C
S
H
Q
Q
S
P
Y
Q
L
L
F
G
E
P
Site 29
Y304
Q
L
L
F
G
E
P
Y
I
F
E
E
L
L
S
Site 30
Y333
T
A
G
A
E
M
L
Y
R
T
V
G
E
L
T
Site 31
S394
A
F
N
G
I
T
N
S
E
F
H
T
G
Q
A
Site 32
S411
I
L
P
G
L
L
K
S
K
E
D
G
Q
S
I
Site 33
S417
K
S
K
E
D
G
Q
S
I
V
A
V
V
N
P
Site 34
Y431
P
A
R
A
G
L
H
Y
K
V
I
Q
A
I
R
Site 35
S457
S
C
K
L
H
G
E
S
T
R
N
V
I
E
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation