KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
DDX27
Full Name:
Probable ATP-dependent RNA helicase DDX27
Alias:
DEAD (Asp-Glu-Ala-Asp) box polypeptide 27; DEAD box protein 27; DJ686N3.1; DKFZp667N057; FLJ12917; FLJ20596; FLJ22238; HSPC259; MGC1018; PP3241; RHLP; Rrp3p
Type:
Helicase; EC 3.6.1.-
Mass (Da):
89817
Number AA:
796
UniProt ID:
Q96GQ7
International Prot ID:
IPI00293078
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0008026
GO:0003676
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S24
G
P
Q
A
V
L
A
S
G
S
G
F
C
D
N
Site 2
S54
E
V
P
V
E
P
E
S
D
S
G
D
E
E
E
Site 3
S56
P
V
E
P
E
S
D
S
G
D
E
E
E
E
G
Site 4
S79
K
A
L
G
K
N
R
S
A
D
F
N
P
D
F
Site 5
T94
V
F
T
E
K
E
G
T
Y
D
G
S
W
A
L
Site 6
Y95
F
T
E
K
E
G
T
Y
D
G
S
W
A
L
A
Site 7
S98
K
E
G
T
Y
D
G
S
W
A
L
A
D
V
M
Site 8
S106
W
A
L
A
D
V
M
S
Q
L
K
K
K
R
A
Site 9
T115
L
K
K
K
R
A
A
T
T
L
D
E
K
I
E
Site 10
T130
K
V
R
K
K
R
K
T
E
D
K
E
A
K
S
Site 11
S137
T
E
D
K
E
A
K
S
G
K
L
E
K
E
K
Site 12
S150
E
K
E
A
K
E
G
S
E
P
K
E
Q
E
D
Site 13
S166
Q
E
N
D
E
E
G
S
E
D
E
A
S
E
T
Site 14
S171
E
G
S
E
D
E
A
S
E
T
D
Y
S
S
A
Site 15
T173
S
E
D
E
A
S
E
T
D
Y
S
S
A
D
E
Site 16
Y175
D
E
A
S
E
T
D
Y
S
S
A
D
E
N
I
Site 17
S176
E
A
S
E
T
D
Y
S
S
A
D
E
N
I
L
Site 18
S177
A
S
E
T
D
Y
S
S
A
D
E
N
I
L
T
Site 19
T184
S
A
D
E
N
I
L
T
K
A
D
T
L
K
V
Site 20
T188
N
I
L
T
K
A
D
T
L
K
V
K
D
R
K
Site 21
S212
G
G
F
F
E
D
A
S
Q
Y
D
E
N
L
S
Site 22
Y214
F
F
E
D
A
S
Q
Y
D
E
N
L
S
F
Q
Site 23
S219
S
Q
Y
D
E
N
L
S
F
Q
D
M
N
L
S
Site 24
S226
S
F
Q
D
M
N
L
S
R
P
L
L
K
A
I
Site 25
T234
R
P
L
L
K
A
I
T
A
M
G
F
K
Q
P
Site 26
T269
A
A
T
G
T
G
K
T
A
A
F
A
L
P
V
Site 27
Y282
P
V
L
E
R
L
I
Y
K
P
R
Q
A
P
V
Site 28
T298
R
V
L
V
L
V
P
T
R
E
L
G
I
Q
V
Site 29
S307
E
L
G
I
Q
V
H
S
V
T
R
Q
L
A
Q
Site 30
T309
G
I
Q
V
H
S
V
T
R
Q
L
A
Q
F
C
Site 31
S331
V
G
G
L
D
V
K
S
Q
E
A
A
L
R
A
Site 32
T346
A
P
D
I
L
I
A
T
P
G
R
L
I
D
H
Site 33
S359
D
H
L
H
N
C
P
S
F
H
L
S
S
I
E
Site 34
Y380
A
D
R
M
L
D
E
Y
F
E
E
Q
M
K
E
Site 35
S414
D
E
V
K
D
L
A
S
V
S
L
K
N
P
V
Site 36
S498
G
E
L
H
G
N
L
S
Q
T
Q
R
L
E
A
Site 37
T500
L
H
G
N
L
S
Q
T
Q
R
L
E
A
L
R
Site 38
T534
L
D
I
E
G
V
K
T
V
I
N
F
T
M
P
Site 39
T539
V
K
T
V
I
N
F
T
M
P
N
T
I
K
H
Site 40
Y547
M
P
N
T
I
K
H
Y
V
H
R
V
G
R
T
Site 41
S563
R
A
G
R
A
G
R
S
V
S
L
V
G
E
D
Site 42
S565
G
R
A
G
R
S
V
S
L
V
G
E
D
E
R
Site 43
Y611
E
K
M
E
K
D
V
Y
A
V
L
Q
L
E
A
Site 44
S626
E
E
K
E
M
Q
Q
S
E
A
Q
I
N
T
A
Site 45
S651
V
V
Q
E
P
E
R
S
W
F
Q
T
K
E
E
Site 46
T655
P
E
R
S
W
F
Q
T
K
E
E
R
K
K
E
Site 47
T695
A
K
K
K
G
E
M
T
A
E
E
R
S
Q
F
Site 48
S746
K
Q
K
Q
G
K
K
S
V
F
D
E
E
L
T
Site 49
T755
F
D
E
E
L
T
N
T
S
K
K
A
L
K
Q
Site 50
S768
K
Q
Y
R
A
G
P
S
F
E
E
R
K
Q
L
Site 51
S788
R
R
G
G
N
F
K
S
K
S
R
Y
K
R
R
Site 52
S790
G
G
N
F
K
S
K
S
R
Y
K
R
R
K
_
Site 53
Y792
N
F
K
S
K
S
R
Y
K
R
R
K
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation