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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM108A1
Full Name:
Abhydrolase domain-containing protein FAM108A1
Alias:
C19orf27; family with sequence similarity 108, member A1; MGC5244
Type:
EC 3.-.-.-; Hydrolase
Mass (Da):
33990
Number AA:
UniProt ID:
Q96GS6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
GO:0016787
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y35
F
L
P
P
E
A
T
Y
S
L
V
P
E
P
E
Site 2
S36
L
P
P
E
A
T
Y
S
L
V
P
E
P
E
P
Site 3
S59
P
L
G
T
L
R
A
S
S
G
A
P
G
R
W
Site 4
S60
L
G
T
L
R
A
S
S
G
A
P
G
R
W
K
Site 5
T71
G
R
W
K
L
H
L
T
E
R
A
D
F
Q
Y
Site 6
Y78
T
E
R
A
D
F
Q
Y
S
Q
R
E
L
D
T
Site 7
S79
E
R
A
D
F
Q
Y
S
Q
R
E
L
D
T
I
Site 8
T85
Y
S
Q
R
E
L
D
T
I
E
V
F
P
T
K
Site 9
T91
D
T
I
E
V
F
P
T
K
S
A
R
G
N
R
Site 10
S93
I
E
V
F
P
T
K
S
A
R
G
N
R
V
S
Site 11
Y145
L
H
C
N
I
F
S
Y
D
Y
S
G
Y
G
A
Site 12
Y147
C
N
I
F
S
Y
D
Y
S
G
Y
G
A
S
S
Site 13
S148
N
I
F
S
Y
D
Y
S
G
Y
G
A
S
S
G
Site 14
Y150
F
S
Y
D
Y
S
G
Y
G
A
S
S
G
R
P
Site 15
S153
D
Y
S
G
Y
G
A
S
S
G
R
P
S
E
R
Site 16
S154
Y
S
G
Y
G
A
S
S
G
R
P
S
E
R
N
Site 17
S158
G
A
S
S
G
R
P
S
E
R
N
L
Y
A
D
Site 18
Y163
R
P
S
E
R
N
L
Y
A
D
I
D
A
A
W
Site 19
Y177
W
Q
A
L
R
T
R
Y
G
I
S
P
D
S
I
Site 20
S180
L
R
T
R
Y
G
I
S
P
D
S
I
I
L
Y
Site 21
S183
R
Y
G
I
S
P
D
S
I
I
L
Y
G
Q
S
Site 22
T196
Q
S
I
G
T
V
P
T
V
D
L
A
S
R
Y
Site 23
S261
E
D
E
V
I
D
F
S
H
G
L
A
L
Y
E
Site 24
Y290
G
H
N
D
I
E
L
Y
S
Q
Y
L
E
R
L
Site 25
S291
H
N
D
I
E
L
Y
S
Q
Y
L
E
R
L
R
Site 26
Y293
D
I
E
L
Y
S
Q
Y
L
E
R
L
R
R
F
Site 27
S302
E
R
L
R
R
F
I
S
Q
E
L
P
S
Q
R
Site 28
S307
F
I
S
Q
E
L
P
S
Q
R
A
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation