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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MYO19
Full Name:
Myosin-XIX
Alias:
Myosin head domain-containing protein 1
Type:
Mass (Da):
109117
Number AA:
970
UniProt ID:
Q96H55
International Prot ID:
IPI00894163
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0016459
GO:0032991
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0003774
GO:0003779
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
V
N
G
H
N
P
G
S
D
G
Q
A
R
E
Y
Site 2
Y19
S
D
G
Q
A
R
E
Y
L
R
E
D
L
Q
E
Site 3
T41
L
Y
K
L
D
D
L
T
R
V
N
P
V
T
L
Site 4
Y65
R
Y
M
A
D
T
F
Y
T
N
A
G
C
T
L
Site 5
S86
K
P
V
P
Q
L
Y
S
P
E
L
M
R
E
Y
Site 6
Y93
S
P
E
L
M
R
E
Y
H
A
A
P
Q
P
Q
Site 7
T108
K
L
K
P
H
V
F
T
V
G
E
Q
T
Y
R
Site 8
S119
Q
T
Y
R
N
V
K
S
L
I
E
P
V
N
Q
Site 9
S131
V
N
Q
S
I
V
V
S
G
E
S
G
A
G
K
Site 10
S134
S
I
V
V
S
G
E
S
G
A
G
K
T
W
T
Site 11
T141
S
G
A
G
K
T
W
T
S
R
C
L
M
K
F
Site 12
S158
V
V
A
T
S
P
A
S
W
E
S
H
K
I
A
Site 13
T187
E
A
F
G
N
A
C
T
L
R
N
N
N
S
S
Site 14
S193
C
T
L
R
N
N
N
S
S
R
F
G
K
F
I
Site 15
S194
T
L
R
N
N
N
S
S
R
F
G
K
F
I
Q
Site 16
T211
L
N
R
A
Q
Q
M
T
G
A
A
V
Q
T
Y
Site 17
Y218
T
G
A
A
V
Q
T
Y
L
L
E
K
T
R
V
Site 18
S230
T
R
V
A
C
Q
A
S
S
E
R
N
F
H
I
Site 19
Y239
E
R
N
F
H
I
F
Y
Q
I
C
K
G
A
S
Site 20
S262
L
P
E
G
A
A
F
S
W
L
P
N
P
E
R
Site 21
S270
W
L
P
N
P
E
R
S
L
E
E
D
C
F
E
Site 22
T292
H
L
G
I
D
T
P
T
Q
N
N
I
F
K
V
Site 23
S314
G
N
I
Q
F
A
A
S
E
D
E
A
Q
P
C
Site 24
Y329
Q
P
M
D
D
A
K
Y
S
V
R
T
A
A
S
Site 25
S330
P
M
D
D
A
K
Y
S
V
R
T
A
A
S
L
Site 26
S336
Y
S
V
R
T
A
A
S
L
L
G
L
P
E
D
Site 27
T353
L
E
M
V
Q
I
R
T
I
R
A
G
R
Q
Q
Site 28
S420
L
D
V
Y
G
F
E
S
F
P
D
N
S
L
E
Site 29
S425
F
E
S
F
P
D
N
S
L
E
Q
L
C
I
N
Site 30
Y446
Q
Q
H
F
V
A
H
Y
L
R
A
Q
Q
E
E
Site 31
Y454
L
R
A
Q
Q
E
E
Y
A
V
E
G
L
E
W
Site 32
Y466
L
E
W
S
F
I
N
Y
Q
D
N
Q
P
C
L
Site 33
S485
G
S
P
I
S
I
C
S
L
I
N
E
E
C
R
Site 34
S497
E
C
R
L
N
R
P
S
S
A
A
Q
L
Q
T
Site 35
S498
C
R
L
N
R
P
S
S
A
A
Q
L
Q
T
R
Site 36
T508
Q
L
Q
T
R
I
E
T
A
L
A
G
S
P
C
Site 37
S513
I
E
T
A
L
A
G
S
P
C
L
G
H
N
K
Site 38
S522
C
L
G
H
N
K
L
S
R
E
P
S
F
I
V
Site 39
S526
N
K
L
S
R
E
P
S
F
I
V
V
H
Y
A
Site 40
T540
A
G
P
V
R
Y
H
T
A
G
L
V
E
K
N
Site 41
S562
L
T
R
L
L
Q
Q
S
Q
D
P
L
L
M
G
Site 42
T579
P
T
N
P
K
E
K
T
Q
E
E
P
P
G
Q
Site 43
S611
Q
L
L
Q
V
L
H
S
T
T
P
H
Y
I
R
Site 44
Y616
L
H
S
T
T
P
H
Y
I
R
C
I
K
P
N
Site 45
S624
I
R
C
I
K
P
N
S
Q
G
Q
A
Q
T
F
Site 46
S661
A
G
F
P
I
R
V
S
H
R
N
F
V
E
R
Site 47
T679
L
R
R
L
H
P
C
T
S
S
G
P
D
S
P
Site 48
S680
R
R
L
H
P
C
T
S
S
G
P
D
S
P
Y
Site 49
S681
R
L
H
P
C
T
S
S
G
P
D
S
P
Y
P
Site 50
S685
C
T
S
S
G
P
D
S
P
Y
P
A
K
G
L
Site 51
Y687
S
S
G
P
D
S
P
Y
P
A
K
G
L
P
E
Site 52
S699
L
P
E
W
C
P
H
S
E
E
A
T
L
E
P
Site 53
T703
C
P
H
S
E
E
A
T
L
E
P
L
I
Q
D
Site 54
S841
G
V
E
E
K
H
F
S
Q
A
P
C
S
L
S
Site 55
S846
H
F
S
Q
A
P
C
S
L
S
T
S
P
L
Q
Site 56
S848
S
Q
A
P
C
S
L
S
T
S
P
L
Q
T
R
Site 57
T873
L
G
L
V
L
A
N
T
A
M
G
V
G
S
F
Site 58
S896
C
L
Q
L
P
R
G
S
P
S
S
Y
T
V
Q
Site 59
S899
L
P
R
G
S
P
S
S
Y
T
V
Q
T
A
Q
Site 60
Y900
P
R
G
S
P
S
S
Y
T
V
Q
T
A
Q
D
Site 61
T901
R
G
S
P
S
S
Y
T
V
Q
T
A
Q
D
Q
Site 62
S913
Q
D
Q
A
G
V
T
S
I
R
A
L
P
Q
G
Site 63
S929
I
K
F
H
C
R
K
S
P
L
R
Y
A
D
I
Site 64
Y933
C
R
K
S
P
L
R
Y
A
D
I
C
P
E
P
Site 65
S941
A
D
I
C
P
E
P
S
P
Y
S
I
T
G
F
Site 66
Y943
I
C
P
E
P
S
P
Y
S
I
T
G
F
N
Q
Site 67
S944
C
P
E
P
S
P
Y
S
I
T
G
F
N
Q
I
Site 68
T962
R
H
R
L
I
H
V
T
S
S
A
F
T
G
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation