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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ERO1L
Full Name:
ERO1-like protein alpha
Alias:
EC 1.8.4.-; ERO1A; ERO1-L; ERO1-L alpha; ERO1-like; ERO1-like protein alph; Oxidoreductin 1-l alpha; Oxidoreductin-1-Lalpha
Type:
EC 1.8.4.-; Oxidoreductase
Mass (Da):
54393
Number AA:
468
UniProt ID:
Q96HE7
International Prot ID:
IPI00386755
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000267
GO:0005624
GO:0005626
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0003824
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006091
GO:0006457
GO:0006458
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
L
G
A
V
W
L
L
S
S
G
H
G
E
E
Q
Site 2
S20
G
A
V
W
L
L
S
S
G
H
G
E
E
Q
P
Site 3
S71
R
L
Q
K
L
L
E
S
D
Y
F
R
Y
Y
K
Site 4
Y73
Q
K
L
L
E
S
D
Y
F
R
Y
Y
K
V
N
Site 5
Y76
L
E
S
D
Y
F
R
Y
Y
K
V
N
L
K
R
Site 6
Y77
E
S
D
Y
F
R
Y
Y
K
V
N
L
K
R
P
Site 7
S106
C
A
V
K
P
C
Q
S
D
E
V
P
D
G
I
Site 8
S115
E
V
P
D
G
I
K
S
A
S
Y
K
Y
S
E
Site 9
S117
P
D
G
I
K
S
A
S
Y
K
Y
S
E
E
A
Site 10
Y118
D
G
I
K
S
A
S
Y
K
Y
S
E
E
A
N
Site 11
S121
K
S
A
S
Y
K
Y
S
E
E
A
N
N
L
I
Site 12
S143
R
L
G
A
V
D
E
S
L
S
E
E
T
Q
K
Site 13
S145
G
A
V
D
E
S
L
S
E
E
T
Q
K
A
V
Site 14
S173
C
E
A
D
D
I
Q
S
P
E
A
E
Y
V
D
Site 15
Y178
I
Q
S
P
E
A
E
Y
V
D
L
L
L
N
P
Site 16
Y188
L
L
L
N
P
E
R
Y
T
G
Y
K
G
P
D
Site 17
T189
L
L
N
P
E
R
Y
T
G
Y
K
G
P
D
A
Site 18
Y191
N
P
E
R
Y
T
G
Y
K
G
P
D
A
W
K
Site 19
T213
E
N
C
F
K
P
Q
T
I
K
R
P
L
N
P
Site 20
S223
R
P
L
N
P
L
A
S
G
Q
G
T
S
E
E
Site 21
T227
P
L
A
S
G
Q
G
T
S
E
E
N
T
F
Y
Site 22
S228
L
A
S
G
Q
G
T
S
E
E
N
T
F
Y
S
Site 23
T232
Q
G
T
S
E
E
N
T
F
Y
S
W
L
E
G
Site 24
Y234
T
S
E
E
N
T
F
Y
S
W
L
E
G
L
C
Site 25
S235
S
E
E
N
T
F
Y
S
W
L
E
G
L
C
V
Site 26
Y248
C
V
E
K
R
A
F
Y
R
L
I
S
G
L
H
Site 27
Y266
N
V
H
L
S
A
R
Y
L
L
Q
E
T
W
L
Site 28
T293
Q
R
F
D
G
I
L
T
E
G
E
G
P
R
R
Site 29
S353
E
I
L
H
E
I
K
S
F
P
L
H
F
D
E
Site 30
S362
P
L
H
F
D
E
N
S
F
F
A
G
D
K
K
Site 31
T405
R
L
W
G
K
L
Q
T
Q
G
L
G
T
A
L
Site 32
S427
L
I
A
N
M
P
E
S
G
P
S
Y
E
F
H
Site 33
S430
N
M
P
E
S
G
P
S
Y
E
F
H
L
T
R
Site 34
Y431
M
P
E
S
G
P
S
Y
E
F
H
L
T
R
Q
Site 35
T436
P
S
Y
E
F
H
L
T
R
Q
E
I
V
S
L
Site 36
S451
F
N
A
F
G
R
I
S
T
S
V
K
E
L
E
Site 37
T452
N
A
F
G
R
I
S
T
S
V
K
E
L
E
N
Site 38
S453
A
F
G
R
I
S
T
S
V
K
E
L
E
N
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation