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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GRAMD3
Full Name:
GRAM domain-containing protein 3
Alias:
FLJ21313; GRAM domain containing 3; GRAM3; HCV NS3 transactivated protein 2; HCV NS3-transactivated 2; HCV NS3-transactivated protein 2; NS3TP2
Type:
Mass (Da):
47869
Number AA:
432
UniProt ID:
Q96HH9
International Prot ID:
IPI00305868
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
K
V
L
G
K
R
E
S
K
L
G
S
A
H
S
Site 2
S26
K
R
E
S
K
L
G
S
A
H
S
E
A
E
N
Site 3
S29
S
K
L
G
S
A
H
S
E
A
E
N
G
V
E
Site 4
S44
E
K
K
K
A
C
R
S
P
T
A
Q
S
P
T
Site 5
T46
K
K
A
C
R
S
P
T
A
Q
S
P
T
P
S
Site 6
S49
C
R
S
P
T
A
Q
S
P
T
P
S
V
E
A
Site 7
T51
S
P
T
A
Q
S
P
T
P
S
V
E
A
D
S
Site 8
S53
T
A
Q
S
P
T
P
S
V
E
A
D
S
P
D
Site 9
S58
T
P
S
V
E
A
D
S
P
D
Q
K
K
I
I
Site 10
S66
P
D
Q
K
K
I
I
S
L
W
S
K
S
S
F
Site 11
S69
K
K
I
I
S
L
W
S
K
S
S
F
D
G
A
Site 12
S71
I
I
S
L
W
S
K
S
S
F
D
G
A
S
L
Site 13
S72
I
S
L
W
S
K
S
S
F
D
G
A
S
L
A
Site 14
S77
K
S
S
F
D
G
A
S
L
A
S
D
K
N
D
Site 15
T87
S
D
K
N
D
C
K
T
E
S
K
N
D
P
K
Site 16
T95
E
S
K
N
D
P
K
T
E
R
K
K
S
S
S
Site 17
S100
K
T
E
R
K
K
S
S
S
S
S
Q
Y
K
A
Site 18
S102
T
E
R
K
K
S
S
S
S
S
Q
Y
K
A
N
Site 19
S104
R
K
K
S
S
S
S
S
Q
Y
K
A
N
M
H
Site 20
Y106
K
S
S
S
S
S
Q
Y
K
A
N
M
H
F
H
Site 21
S118
H
F
H
K
L
F
L
S
V
P
T
E
E
P
L
Site 22
S128
T
E
E
P
L
K
Q
S
F
T
C
A
L
Q
K
Site 23
T161
S
K
V
F
G
K
D
T
K
I
S
I
P
A
F
Site 24
T171
S
I
P
A
F
S
V
T
L
I
K
K
T
K
T
Site 25
Y195
I
A
T
V
T
D
R
Y
I
F
V
S
L
L
S
Site 26
S199
T
D
R
Y
I
F
V
S
L
L
S
R
D
S
T
Site 27
S205
V
S
L
L
S
R
D
S
T
Y
K
L
L
K
S
Site 28
T206
S
L
L
S
R
D
S
T
Y
K
L
L
K
S
V
Site 29
Y207
L
L
S
R
D
S
T
Y
K
L
L
K
S
V
C
Site 30
S212
S
T
Y
K
L
L
K
S
V
C
G
H
L
E
N
Site 31
T220
V
C
G
H
L
E
N
T
S
V
G
N
S
P
N
Site 32
S221
C
G
H
L
E
N
T
S
V
G
N
S
P
N
P
Site 33
S225
E
N
T
S
V
G
N
S
P
N
P
S
S
A
E
Site 34
S229
V
G
N
S
P
N
P
S
S
A
E
N
S
F
R
Site 35
S230
G
N
S
P
N
P
S
S
A
E
N
S
F
R
A
Site 36
S234
N
P
S
S
A
E
N
S
F
R
A
D
R
P
S
Site 37
S241
S
F
R
A
D
R
P
S
S
L
P
L
D
F
N
Site 38
S242
F
R
A
D
R
P
S
S
L
P
L
D
F
N
D
Site 39
S252
L
D
F
N
D
E
F
S
D
L
D
G
V
V
Q
Site 40
Y268
R
R
Q
D
M
E
G
Y
S
S
S
G
S
Q
T
Site 41
S269
R
Q
D
M
E
G
Y
S
S
S
G
S
Q
T
P
Site 42
S270
Q
D
M
E
G
Y
S
S
S
G
S
Q
T
P
E
Site 43
S271
D
M
E
G
Y
S
S
S
G
S
Q
T
P
E
S
Site 44
S273
E
G
Y
S
S
S
G
S
Q
T
P
E
S
E
N
Site 45
T275
Y
S
S
S
G
S
Q
T
P
E
S
E
N
S
R
Site 46
S278
S
G
S
Q
T
P
E
S
E
N
S
R
D
F
H
Site 47
S281
Q
T
P
E
S
E
N
S
R
D
F
H
A
T
E
Site 48
T287
N
S
R
D
F
H
A
T
E
S
Q
T
V
L
N
Site 49
S289
R
D
F
H
A
T
E
S
Q
T
V
L
N
V
S
Site 50
T291
F
H
A
T
E
S
Q
T
V
L
N
V
S
K
G
Site 51
S296
S
Q
T
V
L
N
V
S
K
G
E
A
K
P
T
Site 52
T303
S
K
G
E
A
K
P
T
R
A
D
A
H
V
N
Site 53
S319
V
P
E
G
K
A
K
S
L
P
V
Q
G
L
S
Site 54
T370
Y
M
R
Y
R
I
N
T
L
E
E
Q
L
G
L
Site 55
S380
E
Q
L
G
L
L
T
S
I
V
D
T
H
N
T
Site 56
T384
L
L
T
S
I
V
D
T
H
N
T
E
Q
A
A
Site 57
T387
S
I
V
D
T
H
N
T
E
Q
A
A
P
S
G
Site 58
S393
N
T
E
Q
A
A
P
S
G
L
R
S
Q
V
Q
Site 59
S397
A
A
P
S
G
L
R
S
Q
V
Q
F
N
V
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation