PhosphoNET

           
Protein Info 
   
Short Name:  MED30
Full Name:  Mediator of RNA polymerase II transcription subunit 30
Alias:  Mediator complex subunit 30; Thyroid hormone receptor-associated protein 6; Thyroid hormone receptor-associated protein complex 25 kDa component; TRAP/Mediator complex component TRAP25
Type:  Nuclear receptor co-regulator
Mass (Da):  20277
Number AA:  178
UniProt ID:  Q96HR3
International Prot ID:  IPI00063213
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016592  GO:0005634  GO:0032991 Uniprot OncoNet
Molecular Function:  GO:0016455  GO:0030374  GO:0004872 PhosphoSite+ KinaseNET
Biological Process:  GO:0030521  GO:0045449  GO:0006367 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S2______MSTPPLAAS
Site 2T3_____MSTPPLAASG
Site 3S9STPPLAASGMAPGPF
Site 4S32AREVNTASLCRIGQE
Site 5T40LCRIGQETVQDIVYR
Site 6Y46ETVQDIVYRTMEIFQ
Site 7T76GTYQDRLTKLQDNLR
Site 8S86QDNLRQLSVLFRKLR
Site 9Y96FRKLRLVYDKCNENC
Site 10Y117PVEQLIPYVEEDGSK
Site 11S123PYVEEDGSKNDDRAG
Site 12S136AGPPRFASEERREIA
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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