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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DIRAS2
Full Name:
GTP-binding protein Di-Ras2
Alias:
DIRA2; DIRAS family, GTP-binding RAS-like 2; Di-Ras2; Distinct subgroup of the Ras family member 2; DKFZp761C07121
Type:
G protein; G protein, monomeric (non-Rab)
Mass (Da):
22466
Number AA:
199
UniProt ID:
Q96HU8
International Prot ID:
IPI00063302
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0003924
PhosphoSite+
KinaseNET
Biological Process:
GO:0007264
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
P
E
Q
S
N
D
Y
R
V
A
V
F
G
A
Site 2
T31
V
L
R
F
V
K
G
T
F
R
E
S
Y
I
P
Site 3
S35
V
K
G
T
F
R
E
S
Y
I
P
T
V
E
D
Site 4
Y36
K
G
T
F
R
E
S
Y
I
P
T
V
E
D
T
Site 5
T39
F
R
E
S
Y
I
P
T
V
E
D
T
Y
R
Q
Site 6
T43
Y
I
P
T
V
E
D
T
Y
R
Q
V
I
S
C
Site 7
Y44
I
P
T
V
E
D
T
Y
R
Q
V
I
S
C
D
Site 8
T60
S
I
C
T
L
Q
I
T
D
T
T
G
S
H
Q
Site 9
T62
C
T
L
Q
I
T
D
T
T
G
S
H
Q
F
P
Site 10
S75
F
P
A
M
Q
R
L
S
I
S
K
G
H
A
F
Site 11
S93
Y
S
I
T
S
R
Q
S
L
E
E
L
K
P
I
Site 12
Y101
L
E
E
L
K
P
I
Y
E
Q
I
C
E
I
K
Site 13
S126
V
G
N
K
C
D
E
S
P
S
R
E
V
Q
S
Site 14
S128
N
K
C
D
E
S
P
S
R
E
V
Q
S
S
E
Site 15
S134
P
S
R
E
V
Q
S
S
E
A
E
A
L
A
R
Site 16
T173
L
N
L
E
K
R
R
T
V
S
L
Q
I
D
G
Site 17
S175
L
E
K
R
R
T
V
S
L
Q
I
D
G
K
K
Site 18
S183
L
Q
I
D
G
K
K
S
K
Q
Q
K
R
K
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation