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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SCLY
Full Name:
Selenocysteine lyase
Alias:
Putative selenocysteine lyase; SCL
Type:
Other Amino Acids Metabolism - selenoamino acid; EC 4.4.1.16; Lyase
Mass (Da):
48149
Number AA:
445
UniProt ID:
Q96I15
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0030170
GO:0009000
GO:0016740
PhosphoSite+
KinaseNET
Biological Process:
GO:0006520
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
D
A
P
A
P
A
A
S
Q
P
S
G
C
G
K
Site 2
S20
A
P
A
A
S
Q
P
S
G
C
G
K
H
N
S
Site 3
S27
S
G
C
G
K
H
N
S
P
E
R
K
V
Y
M
Site 4
Y33
N
S
P
E
R
K
V
Y
M
D
Y
N
A
T
T
Site 5
Y36
E
R
K
V
Y
M
D
Y
N
A
T
T
P
L
E
Site 6
T40
Y
M
D
Y
N
A
T
T
P
L
E
P
E
V
I
Site 7
S62
W
E
A
W
G
N
P
S
S
P
Y
S
A
G
R
Site 8
S63
E
A
W
G
N
P
S
S
P
Y
S
A
G
R
K
Site 9
S66
G
N
P
S
S
P
Y
S
A
G
R
K
A
K
D
Site 10
S97
P
Q
D
I
I
F
T
S
G
G
T
E
S
N
N
Site 11
S102
F
T
S
G
G
T
E
S
N
N
L
V
I
H
S
Site 12
T124
N
Q
T
S
K
G
H
T
G
G
H
H
S
P
V
Site 13
S129
G
H
T
G
G
H
H
S
P
V
K
G
A
K
P
Site 14
T140
G
A
K
P
H
F
I
T
S
S
V
E
H
D
S
Site 15
S142
K
P
H
F
I
T
S
S
V
E
H
D
S
I
R
Site 16
S147
T
S
S
V
E
H
D
S
I
R
L
P
L
E
H
Site 17
S172
F
V
P
V
S
K
V
S
G
Q
A
E
V
D
D
Site 18
T192
R
P
T
T
R
L
V
T
I
M
L
A
N
N
E
Site 19
Y280
L
G
E
F
T
P
L
Y
P
M
L
F
G
G
G
Site 20
T296
E
R
N
F
R
P
G
T
E
N
T
P
M
I
A
Site 21
T299
F
R
P
G
T
E
N
T
P
M
I
A
G
L
G
Site 22
Y329
H
M
R
D
V
R
D
Y
L
E
E
R
L
E
A
Site 23
S347
Q
K
R
I
H
L
N
S
Q
F
P
G
T
Q
R
Site 24
T352
L
N
S
Q
F
P
G
T
Q
R
L
P
N
T
C
Site 25
T358
G
T
Q
R
L
P
N
T
C
N
F
S
I
R
G
Site 26
S362
L
P
N
T
C
N
F
S
I
R
G
P
R
L
Q
Site 27
S390
S
V
G
A
A
C
H
S
D
H
G
D
Q
P
S
Site 28
S397
S
D
H
G
D
Q
P
S
P
V
L
L
S
Y
G
Site 29
S402
Q
P
S
P
V
L
L
S
Y
G
V
P
F
D
V
Site 30
S417
A
R
N
A
L
R
L
S
V
G
R
S
T
T
R
Site 31
S421
L
R
L
S
V
G
R
S
T
T
R
A
E
V
D
Site 32
T422
R
L
S
V
G
R
S
T
T
R
A
E
V
D
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation