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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PPP1R16A
Full Name:
Protein phosphatase 1 regulatory subunit 16A
Alias:
Myosin phosphatase targeting 3; Myosin phosphatase-targeting subunit 3; MYPT3; PP16A; Protein phosphatase 1 regulatory 16A; Protein phosphatase 1, regulatory (inhibitor) 16A
Type:
Plasma membrane protein
Mass (Da):
57811
Number AA:
528
UniProt ID:
Q96I34
International Prot ID:
IPI00063273
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0031225
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
M
P
M
V
G
R
M
S
T
Q
E
R
L
K
H
Site 2
T19
P
M
V
G
R
M
S
T
Q
E
R
L
K
H
A
Site 3
S60
R
P
R
K
E
A
A
S
Q
G
L
L
K
Q
V
Site 4
S72
K
Q
V
L
F
P
P
S
V
V
L
L
E
A
A
Site 5
S93
E
V
R
Q
F
L
G
S
G
V
S
P
D
L
A
Site 6
S96
Q
F
L
G
S
G
V
S
P
D
L
A
N
E
D
Site 7
T139
A
C
D
S
E
C
W
T
P
L
H
A
A
A
T
Site 8
T168
A
N
L
L
A
V
N
T
D
G
N
M
P
Y
D
Site 9
T182
D
L
C
D
D
E
Q
T
L
D
C
L
E
T
A
Site 10
T196
A
M
A
D
R
G
I
T
Q
D
S
I
E
A
A
Site 11
S199
D
R
G
I
T
Q
D
S
I
E
A
A
R
A
V
Site 12
S217
R
M
L
D
D
I
R
S
R
L
Q
A
G
A
D
Site 13
S257
L
L
L
E
H
R
A
S
L
S
A
K
D
Q
D
Site 14
S259
L
E
H
R
A
S
L
S
A
K
D
Q
D
G
W
Site 15
S295
G
A
D
L
N
A
K
S
L
M
D
E
T
P
L
Site 16
T300
A
K
S
L
M
D
E
T
P
L
D
V
C
G
D
Site 17
S329
D
A
L
L
R
A
Q
S
R
Q
R
S
L
L
R
Site 18
S333
R
A
Q
S
R
Q
R
S
L
L
R
R
R
T
S
Site 19
T339
R
S
L
L
R
R
R
T
S
S
A
G
S
R
G
Site 20
S340
S
L
L
R
R
R
T
S
S
A
G
S
R
G
K
Site 21
S341
L
L
R
R
R
T
S
S
A
G
S
R
G
K
V
Site 22
S344
R
R
T
S
S
A
G
S
R
G
K
V
V
R
R
Site 23
S353
G
K
V
V
R
R
V
S
L
T
Q
R
T
D
L
Site 24
T355
V
V
R
R
V
S
L
T
Q
R
T
D
L
Y
R
Site 25
Y361
L
T
Q
R
T
D
L
Y
R
K
Q
H
A
Q
E
Site 26
T378
V
W
Q
Q
P
P
P
T
S
P
E
P
P
E
D
Site 27
S379
W
Q
Q
P
P
P
T
S
P
E
P
P
E
D
N
Site 28
T391
E
D
N
D
D
R
Q
T
G
A
E
L
R
P
P
Site 29
S418
H
N
G
R
V
G
G
S
P
V
R
H
L
Y
S
Site 30
Y424
G
S
P
V
R
H
L
Y
S
K
R
L
D
R
S
Site 31
S425
S
P
V
R
H
L
Y
S
K
R
L
D
R
S
V
Site 32
S431
Y
S
K
R
L
D
R
S
V
S
Y
Q
L
S
P
Site 33
S433
K
R
L
D
R
S
V
S
Y
Q
L
S
P
L
D
Site 34
Y434
R
L
D
R
S
V
S
Y
Q
L
S
P
L
D
S
Site 35
S437
R
S
V
S
Y
Q
L
S
P
L
D
S
T
T
P
Site 36
S441
Y
Q
L
S
P
L
D
S
T
T
P
H
T
L
V
Site 37
T443
L
S
P
L
D
S
T
T
P
H
T
L
V
H
D
Site 38
T446
L
D
S
T
T
P
H
T
L
V
H
D
K
A
H
Site 39
S478
P
P
P
E
G
P
E
S
P
E
T
A
E
P
G
Site 40
T481
E
G
P
E
S
P
E
T
A
E
P
G
L
P
G
Site 41
T490
E
P
G
L
P
G
D
T
V
T
P
Q
P
D
C
Site 42
T492
G
L
P
G
D
T
V
T
P
Q
P
D
C
G
F
Site 43
T511
D
P
P
L
L
K
L
T
A
P
A
V
E
A
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation