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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RCC1-like GEF
Full Name:
Williams-Beuren syndrome chromosomal region 16 protein
Alias:
RCC1-like G exchanging factor-like protein; WBS16; WBSCR16; Williams-Beuren syndrome chromosome region 16; Williams-Beuren syndrome chromosome region 16 protein; WS16
Type:
Guanine nucleotide exchange factor, misc.
Mass (Da):
49997
Number AA:
464
UniProt ID:
Q96I51
International Prot ID:
IPI00305992
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
A
R
L
G
R
R
L
S
G
P
G
L
G
R
G
Site 2
T27
G
L
G
R
G
H
W
T
A
A
R
R
S
R
S
Site 3
S32
H
W
T
A
A
R
R
S
R
S
R
R
E
A
A
Site 4
S34
T
A
A
R
R
S
R
S
R
R
E
A
A
E
A
Site 5
Y50
A
E
V
P
V
V
Q
Y
V
G
E
R
A
A
R
Site 6
S82
P
S
F
V
V
P
S
S
G
P
G
P
R
A
G
Site 7
S110
L
E
L
D
Q
K
I
S
S
A
A
C
G
Y
G
Site 8
S123
Y
G
F
T
L
L
S
S
K
T
A
D
V
T
K
Site 9
T129
S
S
K
T
A
D
V
T
K
V
W
G
M
G
L
Site 10
S140
G
M
G
L
N
K
D
S
Q
L
G
F
H
R
S
Site 11
S147
S
Q
L
G
F
H
R
S
R
K
D
K
T
R
G
Site 12
T152
H
R
S
R
K
D
K
T
R
G
Y
E
Y
V
L
Site 13
Y155
R
K
D
K
T
R
G
Y
E
Y
V
L
E
P
S
Site 14
Y157
D
K
T
R
G
Y
E
Y
V
L
E
P
S
P
V
Site 15
S162
Y
E
Y
V
L
E
P
S
P
V
S
L
P
L
D
Site 16
S165
V
L
E
P
S
P
V
S
L
P
L
D
R
P
Q
Site 17
S180
E
T
R
V
L
Q
V
S
C
G
R
A
H
S
L
Site 18
S186
V
S
C
G
R
A
H
S
L
V
L
T
D
R
E
Site 19
T190
R
A
H
S
L
V
L
T
D
R
E
G
V
F
S
Site 20
S197
T
D
R
E
G
V
F
S
M
G
N
N
S
Y
G
Site 21
Y216
K
V
V
E
N
E
I
Y
S
E
S
H
R
V
H
Site 22
S217
V
V
E
N
E
I
Y
S
E
S
H
R
V
H
R
Site 23
S242
V
A
C
G
Q
D
H
S
L
F
L
T
D
K
G
Site 24
T246
Q
D
H
S
L
F
L
T
D
K
G
E
V
Y
S
Site 25
Y252
L
T
D
K
G
E
V
Y
S
C
G
W
G
A
D
Site 26
Y267
G
Q
T
G
L
G
H
Y
N
I
T
S
S
P
T
Site 27
T270
G
L
G
H
Y
N
I
T
S
S
P
T
K
L
G
Site 28
S271
L
G
H
Y
N
I
T
S
S
P
T
K
L
G
G
Site 29
S272
G
H
Y
N
I
T
S
S
P
T
K
L
G
G
D
Site 30
S310
G
L
F
G
W
G
N
S
E
Y
L
Q
L
A
S
Site 31
Y312
F
G
W
G
N
S
E
Y
L
Q
L
A
S
V
T
Site 32
S317
S
E
Y
L
Q
L
A
S
V
T
D
S
T
Q
V
Site 33
S321
Q
L
A
S
V
T
D
S
T
Q
V
N
V
P
R
Site 34
T322
L
A
S
V
T
D
S
T
Q
V
N
V
P
R
C
Site 35
S333
V
P
R
C
L
H
F
S
G
V
G
K
V
R
Q
Site 36
S374
K
G
P
N
L
V
E
S
A
V
P
E
M
I
P
Site 37
S397
F
N
P
E
I
Q
V
S
R
I
R
C
G
L
S
Site 38
Y435
I
G
R
L
E
D
Q
Y
F
P
W
R
V
T
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation