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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IGSF21
Full Name:
Immunoglobulin superfamily member 21
Alias:
Type:
Mass (Da):
51835
Number AA:
467
UniProt ID:
Q96ID5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T50
T
L
K
C
N
F
K
T
D
G
R
M
R
E
I
Site 2
Y60
R
M
R
E
I
V
W
Y
R
V
T
D
G
G
T
Site 3
T63
E
I
V
W
Y
R
V
T
D
G
G
T
I
K
Q
Site 4
Y83
D
A
M
F
S
T
N
Y
S
H
M
E
N
Y
R
Site 5
Y97
R
K
R
E
D
L
V
Y
Q
S
T
V
R
L
P
Site 6
T100
E
D
L
V
Y
Q
S
T
V
R
L
P
E
V
R
Site 7
S109
R
L
P
E
V
R
I
S
D
N
G
P
Y
E
C
Site 8
Y114
R
I
S
D
N
G
P
Y
E
C
H
V
G
I
Y
Site 9
Y121
Y
E
C
H
V
G
I
Y
D
R
A
T
R
E
K
Site 10
S159
A
D
T
P
A
P
F
S
R
Y
Q
A
Q
N
F
Site 11
Y182
G
K
P
A
P
M
V
Y
F
K
R
D
G
E
P
Site 12
S196
P
I
D
A
V
P
L
S
E
P
P
A
A
S
S
Site 13
S202
L
S
E
P
P
A
A
S
S
G
P
L
Q
D
S
Site 14
S203
S
E
P
P
A
A
S
S
G
P
L
Q
D
S
R
Site 15
S209
S
S
G
P
L
Q
D
S
R
P
F
R
S
L
L
Site 16
T223
L
H
R
D
L
D
D
T
K
M
Q
K
S
L
S
Site 17
S228
D
D
T
K
M
Q
K
S
L
S
L
L
D
A
E
Site 18
S230
T
K
M
Q
K
S
L
S
L
L
D
A
E
N
R
Site 19
Y242
E
N
R
G
G
R
P
Y
T
E
R
P
S
R
G
Site 20
T243
N
R
G
G
R
P
Y
T
E
R
P
S
R
G
L
Site 21
S247
R
P
Y
T
E
R
P
S
R
G
L
T
P
D
P
Site 22
T251
E
R
P
S
R
G
L
T
P
D
P
N
I
L
L
Site 23
T268
T
T
E
N
I
P
E
T
V
V
S
R
E
F
P
Site 24
S271
N
I
P
E
T
V
V
S
R
E
F
P
R
W
V
Site 25
T284
W
V
H
S
A
E
P
T
Y
F
L
R
H
S
R
Site 26
Y285
V
H
S
A
E
P
T
Y
F
L
R
H
S
R
T
Site 27
S290
P
T
Y
F
L
R
H
S
R
T
P
S
S
D
G
Site 28
T292
Y
F
L
R
H
S
R
T
P
S
S
D
G
T
V
Site 29
S294
L
R
H
S
R
T
P
S
S
D
G
T
V
E
V
Site 30
S295
R
H
S
R
T
P
S
S
D
G
T
V
E
V
R
Site 31
T298
R
T
P
S
S
D
G
T
V
E
V
R
A
L
L
Site 32
T308
V
R
A
L
L
T
W
T
L
N
P
Q
I
D
N
Site 33
S329
E
V
K
H
P
A
L
S
M
P
M
Q
A
E
V
Site 34
T349
K
G
P
K
I
V
M
T
P
S
R
A
R
V
G
Site 35
S351
P
K
I
V
M
T
P
S
R
A
R
V
G
D
T
Site 36
T358
S
R
A
R
V
G
D
T
V
R
I
L
V
H
G
Site 37
T377
V
F
P
E
P
M
F
T
W
T
R
V
G
S
R
Site 38
T379
P
E
P
M
F
T
W
T
R
V
G
S
R
L
L
Site 39
S383
F
T
W
T
R
V
G
S
R
L
L
D
G
S
A
Site 40
S389
G
S
R
L
L
D
G
S
A
E
F
D
G
K
E
Site 41
S409
V
P
A
E
L
N
G
S
M
Y
R
C
T
A
Q
Site 42
Y411
A
E
L
N
G
S
M
Y
R
C
T
A
Q
N
P
Site 43
T414
N
G
S
M
Y
R
C
T
A
Q
N
P
L
G
S
Site 44
T424
N
P
L
G
S
T
D
T
H
T
R
L
I
V
F
Site 45
T426
L
G
S
T
D
T
H
T
R
L
I
V
F
E
N
Site 46
T440
N
P
N
I
P
R
G
T
E
D
S
N
G
S
I
Site 47
S443
I
P
R
G
T
E
D
S
N
G
S
I
G
P
T
Site 48
S446
G
T
E
D
S
N
G
S
I
G
P
T
G
A
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation